Yin Q - Search Results

1

A DNA-encoded library for the identification of natural product binders that modulate poly (ADP-ribose) polymerase 1, a validated anti-cancer target.

Li J, Li Y, Lu F, Liu L, Ji Q, Song K, Yin Q, Lerner RA, Yang G, Xu H, Ma P. Li J, et al. Among authors: yin q. Biochem Biophys Res Commun. 2020 Dec 3;533(2):241-248. doi: 10.1016/j.bbrc.2020.04.022. Epub 2020 May 4. Biochem Biophys Res Commun. 2020. PMID: 32381359

2

2-Bromopalmitate targets retinoic acid receptor alpha and overcomes all-trans retinoic acid resistance of acute promyelocytic leukemia.

Lu Y, Yan JS, Xia L, Qin K, Yin QQ, Xu HT, Gao MQ, Qu XN, Sun YT, Chen GQ. Lu Y, et al. Haematologica. 2019 Jan;104(1):102-112. doi: 10.3324/haematol.2018.191916. Epub 2018 Aug 3. Haematologica. 2019. PMID: 30076181 Free PMC article.

3

Inhibition of mitochondrial complex III induces differentiation in acute myeloid leukemia.

Zhang Y, Luo T, Ding X, Chang Y, Liu C, Zhang Y, Hao S, Yin Q, Jiang B. Zhang Y, et al. Among authors: yin q. Biochem Biophys Res Commun. 2021 Apr 2;547:162-168. doi: 10.1016/j.bbrc.2021.02.027. Epub 2021 Feb 18. Biochem Biophys Res Commun. 2021. PMID: 33610916

4

Cbx4 governs HIF-1α to potentiate angiogenesis of hepatocellular carcinoma by its SUMO E3 ligase activity.

Li J, Xu Y, Long XD, Wang W, Jiao HK, Mei Z, Yin QQ, Ma LN, Zhou AW, Wang LS, Yao M, Xia Q, Chen GQ. Li J, et al. Among authors: yin qq. Cancer Cell. 2014 Jan 13;25(1):118-31. doi: 10.1016/j.ccr.2013.12.008. Cancer Cell. 2014. PMID: 24434214 Free article.

5

Discovery of a Brigatinib Degrader SIAIS164018 with Destroying Metastasis-Related Oncoproteins and a Reshuffling Kinome Profile.

Ren C, Sun N, Liu H, Kong Y, Sun R, Qiu X, Chen J, Li Y, Zhang J, Zhou Y, Zhong H, Yin Q, Song X, Yang X, Jiang B. Ren C, et al. Among authors: yin q. J Med Chem. 2021 Jul 8;64(13):9152-9165. doi: 10.1021/acs.jmedchem.1c00373. Epub 2021 Jun 17. J Med Chem. 2021. PMID: 34138566

6

Optimization of novel benzofuro[3,2-b]pyridin-2(1H)-one derivatives as dual inhibitors of BTK and PI3Kδ.

Liu L, Li X, Cheng Y, Wang L, Yang H, Li J, He S, Shuangjie Wu, Yin Q, Xiang H. Liu L, et al. Among authors: yin q. Eur J Med Chem. 2019 Feb 15;164:304-316. doi: 10.1016/j.ejmech.2018.12.055. Epub 2018 Dec 26. Eur J Med Chem. 2019. PMID: 30605829

7

Discovery of SIAIS178 as an Effective BCR-ABL Degrader by Recruiting Von Hippel-Lindau (VHL) E3 Ubiquitin Ligase.

Zhao Q, Ren C, Liu L, Chen J, Shao Y, Sun N, Sun R, Kong Y, Ding X, Zhang X, Xu Y, Yang B, Yin Q, Yang X, Jiang B. Zhao Q, et al. Among authors: yin q. J Med Chem. 2019 Oct 24;62(20):9281-9298. doi: 10.1021/acs.jmedchem.9b01264. Epub 2019 Oct 2. J Med Chem. 2019. PMID: 31539241

8

Discovery of novel BCR-ABL PROTACs based on the cereblon E3 ligase design, synthesis, and biological evaluation.

Liu H, Ding X, Liu L, Mi Q, Zhao Q, Shao Y, Ren C, Chen J, Kong Y, Qiu X, Elvassore N, Yang X, Yin Q, Jiang B. Liu H, et al. Among authors: yin q. Eur J Med Chem. 2021 Nov 5;223:113645. doi: 10.1016/j.ejmech.2021.113645. Epub 2021 Jun 25. Eur J Med Chem. 2021. PMID: 34217059

9

Tenascin C⁺ papillary fibroblasts facilitate neuro-immune interaction in a mouse model of psoriasis.

Cai X, Han M, Lou F, Sun Y, Yin Q, Sun L, Wang Z, Li X, Zhou H, Xu Z, Wang H, Deng S, Zheng X, Zhang T, Li Q, Zhou B, Wang H. Cai X, et al. Among authors: yin q. Nat Commun. 2023 Apr 10;14(1):2004. doi: 10.1038/s41467-023-37798-x. Nat Commun. 2023. PMID: 37037861 Free PMC article.

10

Identification of a natural inhibitor of methionine adenosyltransferase 2A regulating one-carbon metabolism in keratinocytes.

Bai J, Gao Y, Chen L, Yin Q, Lou F, Wang Z, Xu Z, Zhou H, Li Q, Cai W, Sun Y, Niu L, Wang H, Wei Z, Lu S, Zhou A, Zhang J, Wang H. Bai J, et al. Among authors: yin q. EBioMedicine. 2019 Jan;39:575-590. doi: 10.1016/j.ebiom.2018.12.036. Epub 2018 Dec 25. EBioMedicine. 2019. PMID: 30591370 Free PMC article.

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