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2,462 results

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Entrectinib, a TRK/ROS1 inhibitor with anti-CNS tumor activity: differentiation from other inhibitors in its class due to weak interaction with P-glycoprotein.
Fischer H, Ullah M, de la Cruz CC, Hunsaker T, Senn C, Wirz T, Wagner B, Draganov D, Vazvaei F, Donzelli M, Paehler A, Merchant M, Yu L. Fischer H, et al. Among authors: wagner b. Neuro Oncol. 2020 Jun 9;22(6):819-829. doi: 10.1093/neuonc/noaa052. Neuro Oncol. 2020. PMID: 32383735 Free PMC article.
Synthesis of azaspirocycles and their evaluation in drug discovery.
Burkhard JA, Wagner B, Fischer H, Schuler F, Müller K, Carreira EM. Burkhard JA, et al. Among authors: wagner b. Angew Chem Int Ed Engl. 2010 May 3;49(20):3524-7. doi: 10.1002/anie.200907108. Angew Chem Int Ed Engl. 2010. PMID: 20544904 No abstract available.
Oxetanes as promising modules in drug discovery.
Wuitschik G, Rogers-Evans M, Müller K, Fischer H, Wagner B, Schuler F, Polonchuk L, Carreira EM. Wuitschik G, et al. Among authors: wagner b. Angew Chem Int Ed Engl. 2006 Nov 27;45(46):7736-9. doi: 10.1002/anie.200602343. Angew Chem Int Ed Engl. 2006. PMID: 17013952 No abstract available.
Oxetanes in drug discovery: structural and synthetic insights.
Wuitschik G, Carreira EM, Wagner B, Fischer H, Parrilla I, Schuler F, Rogers-Evans M, Müller K. Wuitschik G, et al. Among authors: wagner b. J Med Chem. 2010 Apr 22;53(8):3227-46. doi: 10.1021/jm9018788. J Med Chem. 2010. PMID: 20349959
A fluorine scan of the phenylamidinium needle of tricyclic thrombin inhibitors: effects of fluorine substitution on pKa and binding affinity and evidence for intermolecular C-F...CN interactions.
Olsen J, Seiler P, Wagner B, Fischer H, Tschopp T, Obst-Sander U, Banner DW, Kansy M, Müller K, Diederich F. Olsen J, et al. Among authors: wagner b. Org Biomol Chem. 2004 May 7;2(9):1339-52. doi: 10.1039/b402515f. Epub 2004 Apr 14. Org Biomol Chem. 2004. PMID: 15105924
Predicting and tuning physicochemical properties in lead optimization: amine basicities.
Morgenthaler M, Schweizer E, Hoffmann-Röder A, Benini F, Martin RE, Jaeschke G, Wagner B, Fischer H, Bendels S, Zimmerli D, Schneider J, Diederich F, Kansy M, Müller K. Morgenthaler M, et al. Among authors: wagner b. ChemMedChem. 2007 Aug;2(8):1100-15. doi: 10.1002/cmdc.200700059. ChemMedChem. 2007. PMID: 17530727 Review.
2,462 results