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Page 1
Reconstruction of the mouse extrahepatic biliary tree using primary human extrahepatic cholangiocyte organoids.
Sampaziotis F, Justin AW, Tysoe OC, Sawiak S, Godfrey EM, Upponi SS, Gieseck RL 3rd, de Brito MC, Berntsen NL, Gómez-Vázquez MJ, Ortmann D, Yiangou L, Ross A, Bargehr J, Bertero A, Zonneveld MCF, Pedersen MT, Pawlowski M, Valestrand L, Madrigal P, Georgakopoulos N, Pirmadjid N, Skeldon GM, Casey J, Shu W, Materek PM, Snijders KE, Brown SE, Rimland CA, Simonic I, Davies SE, Jensen KB, Zilbauer M, Gelson WTH, Alexander GJ, Sinha S, Hannan NRF, Wynn TA, Karlsen TH, Melum E, Markaki AE, Saeb-Parsy K, Vallier L. Sampaziotis F, et al. Among authors: gieseck rl 3rd. Nat Med. 2017 Aug;23(8):954-963. doi: 10.1038/nm.4360. Epub 2017 Jul 3. Nat Med. 2017. PMID: 28671689 Free article.
Type 2 immunity is protective in metabolic disease but exacerbates NAFLD collaboratively with TGF-β.
Hart KM, Fabre T, Sciurba JC, Gieseck RL 3rd, Borthwick LA, Vannella KM, Acciani TH, de Queiroz Prado R, Thompson RW, White S, Soucy G, Bilodeau M, Ramalingam TR, Arron JR, Shoukry NH, Wynn TA. Hart KM, et al. Among authors: gieseck rl 3rd. Sci Transl Med. 2017 Jun 28;9(396):eaal3694. doi: 10.1126/scitranslmed.aal3694. Sci Transl Med. 2017. PMID: 28659437
TH2 and TH17 inflammatory pathways are reciprocally regulated in asthma.
Choy DF, Hart KM, Borthwick LA, Shikotra A, Nagarkar DR, Siddiqui S, Jia G, Ohri CM, Doran E, Vannella KM, Butler CA, Hargadon B, Sciurba JC, Gieseck RL, Thompson RW, White S, Abbas AR, Jackman J, Wu LC, Egen JG, Heaney LG, Ramalingam TR, Arron JR, Wynn TA, Bradding P. Choy DF, et al. Among authors: gieseck rl. Sci Transl Med. 2015 Aug 19;7(301):301ra129. doi: 10.1126/scitranslmed.aab3142. Sci Transl Med. 2015. PMID: 26290411
Anti-IL-13Rα2 therapy promotes recovery in a murine model of inflammatory bowel disease.
Karmele EP, Pasricha TS, Ramalingam TR, Thompson RW, Gieseck RL 3rd, Knilans KJ, Hegen M, Farmer M, Jin F, Kleinman A, Hinds DA; 23andMe Research Team; Almeida Pereira T, de Queiroz Prado R, Bing N, Tchistiakova L, Kasaian MT, Wynn TA, Vannella KM. Karmele EP, et al. Among authors: gieseck rl 3rd. Mucosal Immunol. 2019 Sep;12(5):1174-1186. doi: 10.1038/s41385-019-0189-6. Epub 2019 Jul 15. Mucosal Immunol. 2019. PMID: 31308480 Free PMC article.
Cholangiocyte organoids can repair bile ducts after transplantation in the human liver.
Sampaziotis F, Muraro D, Tysoe OC, Sawiak S, Beach TE, Godfrey EM, Upponi SS, Brevini T, Wesley BT, Garcia-Bernardo J, Mahbubani K, Canu G, Gieseck R 3rd, Berntsen NL, Mulcahy VL, Crick K, Fear C, Robinson S, Swift L, Gambardella L, Bargehr J, Ortmann D, Brown SE, Osnato A, Murphy MP, Corbett G, Gelson WTH, Mells GF, Humphreys P, Davies SE, Amin I, Gibbs P, Sinha S, Teichmann SA, Butler AJ, See TC, Melum E, Watson CJE, Saeb-Parsy K, Vallier L. Sampaziotis F, et al. Science. 2021 Feb 19;371(6531):839-846. doi: 10.1126/science.aaz6964. Science. 2021. PMID: 33602855 Free PMC article.
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