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MEK inhibition induces MYOG and remodels super-enhancers in RAS-driven rhabdomyosarcoma.
Yohe ME, Gryder BE, Shern JF, Song YK, Chou HC, Sindiri S, Mendoza A, Patidar R, Zhang X, Guha R, Butcher D, Isanogle KA, Robinson CM, Luo X, Chen JQ, Walton A, Awasthi P, Edmondson EF, Difilippantonio S, Wei JS, Zhao K, Ferrer M, Thomas CJ, Khan J. Yohe ME, et al. Sci Transl Med. 2018 Jul 4;10(448):eaan4470. doi: 10.1126/scitranslmed.aan4470. Sci Transl Med. 2018. PMID: 29973406 Free PMC article.
Reactive astrocytic S1P3 signaling modulates the blood-tumor barrier in brain metastases.
Gril B, Paranjape AN, Woditschka S, Hua E, Dolan EL, Hanson J, Wu X, Kloc W, Izycka-Swieszewska E, Duchnowska R, Pęksa R, Biernat W, Jassem J, Nayyar N, Brastianos PK, Hall OM, Peer CJ, Figg WD, Pauly GT, Robinson C, Difilippantonio S, Bialecki E, Metellus P, Schneider JP, Steeg PS. Gril B, et al. Among authors: robinson c. Nat Commun. 2018 Jul 13;9(1):2705. doi: 10.1038/s41467-018-05030-w. Nat Commun. 2018. PMID: 30006619 Free PMC article.
A Nonaggregating Heptamethine Cyanine for Building Brighter Labeled Biomolecules.
Luciano MP, Crooke SN, Nourian S, Dingle I, Nani RR, Kline G, Patel NL, Robinson CM, Difilippantonio S, Kalen JD, Finn MG, Schnermann MJ. Luciano MP, et al. ACS Chem Biol. 2019 May 17;14(5):934-940. doi: 10.1021/acschembio.9b00122. Epub 2019 Apr 27. ACS Chem Biol. 2019. PMID: 31030512 Free PMC article.
TNIK Is a Therapeutic Target in Lung Squamous Cell Carcinoma and Regulates FAK Activation through Merlin.
Torres-Ayuso P, An E, Nyswaner KM, Bensen RC, Ritt DA, Specht SI, Das S, Andresson T, Cachau RE, Liang RJ, Ries AL, Robinson CM, Difilippantonio S, Gouker B, Bassel L, Karim BO, Miller CJ, Turk BE, Morrison DK, Brognard J. Torres-Ayuso P, et al. Among authors: robinson cm. Cancer Discov. 2021 Jun;11(6):1411-1423. doi: 10.1158/2159-8290.CD-20-0797. Epub 2021 Jan 25. Cancer Discov. 2021. PMID: 33495197 Free PMC article.
Aging and CNS Myeloid Cell Depletion Attenuate Breast Cancer Brain Metastasis.
Wu AML, Gossa S, Samala R, Chung MA, Gril B, Yang HH, Thorsheim HR, Tran AD, Wei D, Taner E, Isanogle K, Yang Y, Dolan EL, Robinson C, Difilippantonio S, Lee MP, Khan I, Smith QR, McGavern DB, Wakefield LM, Steeg PS. Wu AML, et al. Among authors: robinson c. Clin Cancer Res. 2021 Aug 1;27(15):4422-4434. doi: 10.1158/1078-0432.CCR-21-1549. Epub 2021 Jun 3. Clin Cancer Res. 2021. PMID: 34083229 Free PMC article.
Targeted multicolor in vivo imaging over 1,000 nm enabled by nonamethine cyanines.
Bandi VG, Luciano MP, Saccomano M, Patel NL, Bischof TS, Lingg JGP, Tsrunchev PT, Nix MN, Ruehle B, Sanders C, Riffle L, Robinson CM, Difilippantonio S, Kalen JD, Resch-Genger U, Ivanic J, Bruns OT, Schnermann MJ. Bandi VG, et al. Among authors: robinson cm. Nat Methods. 2022 Mar;19(3):353-358. doi: 10.1038/s41592-022-01394-6. Epub 2022 Feb 28. Nat Methods. 2022. PMID: 35228725
The Combination of Trametinib and Ganitumab is Effective in RAS-Mutated PAX-Fusion Negative Rhabdomyosarcoma Models.
Hebron KE, Wan X, Roth JS, Liewehr DJ, Sealover NE, Frye WJE, Kim A, Stauffer S, Perkins OL, Sun W, Isanogle KA, Robinson CM, James A, Awasthi P, Shankarappa P, Luo X, Lei H, Butcher D, Smith R, Edmondson EF, Chen JQ, Kedei N, Peer CJ, Shern JF, Figg WD, Chen L, Hall MD, Difilippantonio S, Barr FG, Kortum RL, Robey RW, Vaseva AV, Khan J, Yohe ME. Hebron KE, et al. Clin Cancer Res. 2023 Jan 17;29(2):472-487. doi: 10.1158/1078-0432.CCR-22-1646. Clin Cancer Res. 2023. PMID: 36322002 Free PMC article.
Comparison of Three Transcytotic Pathways for Distribution to Brain Metastases of Breast Cancer.
Khan I, Gril B, Paranjape AN, Robinson CM, Difilippantonio S, Biernat W, Bieńkowski M, Pęksa R, Duchnowska R, Jassem J, Brastianos PK, Metellus P, Bialecki E, Woodroofe CC, Wu H, Swenson RE, Steeg PS. Khan I, et al. Among authors: robinson cm. Mol Cancer Ther. 2023 May 4;22(5):646-658. doi: 10.1158/1535-7163.MCT-22-0815. Mol Cancer Ther. 2023. PMID: 36912773 Free PMC article.
Preclinical Evaluation of the FGFR-Family Inhibitor Futibatinib for Pediatric Rhabdomyosarcoma.
Wu JT, Cheuk A, Isanogle K, Robinson C, Zhang X, Ceribelli M, Beck E, Shinn P, Klumpp-Thomas C, Wilson KM, McKnight C, Itkin Z, Sotome H, Hirai H, Calleja E, Wacheck V, Gouker B, Peer CJ, Corvalan N, Milewski D, Kim YY, Figg WD, Edmondson EF, Thomas CJ, Difilippantonio S, Wei JS, Khan J. Wu JT, et al. Among authors: robinson c. Cancers (Basel). 2023 Aug 9;15(16):4034. doi: 10.3390/cancers15164034. Cancers (Basel). 2023. PMID: 37627061 Free PMC article.
4,480 results