Hui KPY - Search Results

1

Tropism, replication competence, and innate immune responses of the coronavirus SARS-CoV-2 in human respiratory tract and conjunctiva: an analysis in ex-vivo and in-vitro cultures.

Hui KPY, Cheung MC, Perera RAPM, Ng KC, Bui CHT, Ho JCW, Ng MMT, Kuok DIT, Shih KC, Tsao SW, Poon LLM, Peiris M, Nicholls JM, Chan MCW. Hui KPY, et al. Lancet Respir Med. 2020 Jul;8(7):687-695. doi: 10.1016/S2213-2600(20)30193-4. Epub 2020 May 7. Lancet Respir Med. 2020. PMID: 32386571 Free PMC article.

2

Hyperinduction of cyclooxygenase-2-mediated proinflammatory cascade: a mechanism for the pathogenesis of avian influenza H5N1 infection.

Lee SM, Cheung CY, Nicholls JM, Hui KP, Leung CY, Uiprasertkul M, Tipoe GL, Lau YL, Poon LL, Ip NY, Guan Y, Peiris JS. Lee SM, et al. J Infect Dis. 2008 Aug 15;198(4):525-35. doi: 10.1086/590499. J Infect Dis. 2008. PMID: 18613795

3

Induction of proinflammatory cytokines in primary human macrophages by influenza A virus (H5N1) is selectively regulated by IFN regulatory factor 3 and p38 MAPK.

Hui KP, Lee SM, Cheung CY, Ng IH, Poon LL, Guan Y, Ip NY, Lau AS, Peiris JS. Hui KP, et al. J Immunol. 2009 Jan 15;182(2):1088-98. doi: 10.4049/jimmunol.182.2.1088. J Immunol. 2009. PMID: 19124752

4

H5N1 influenza virus-induced mediators upregulate RIG-I in uninfected cells by paracrine effects contributing to amplified cytokine cascades.

Hui KP, Lee SM, Cheung CY, Mao H, Lai AK, Chan RW, Chan MC, Tu W, Guan Y, Lau YL, Peiris JS. Hui KP, et al. J Infect Dis. 2011 Dec 15;204(12):1866-78. doi: 10.1093/infdis/jir665. Epub 2011 Oct 19. J Infect Dis. 2011. PMID: 22013225

5

Tropism and innate host responses of a novel avian influenza A H7N9 virus: an analysis of ex-vivo and in-vitro cultures of the human respiratory tract.

Chan MC, Chan RW, Chan LL, Mok CK, Hui KP, Fong JH, Tao KP, Poon LL, Nicholls JM, Guan Y, Peiris JS. Chan MC, et al. Lancet Respir Med. 2013 Sep;1(7):534-42. doi: 10.1016/S2213-2600(13)70138-3. Epub 2013 Jul 25. Lancet Respir Med. 2013. PMID: 24461614 Free PMC article.

6

Highly pathogenic avian influenza A H5N1 and pandemic H1N1 virus infections have different phenotypes in Toll-like receptor 3 knockout mice.

Leung YHC, Nicholls JM, Ho CK, Sia SF, Mok CKP, Valkenburg SA, Cheung P, Hui KPY, Chan RWY, Guan Y, Akira S, Peiris JSM. Leung YHC, et al. Among authors: hui kpy. J Gen Virol. 2014 Sep;95(Pt 9):1870-1879. doi: 10.1099/vir.0.066258-0. Epub 2014 May 30. J Gen Virol. 2014. PMID: 24878639 Free PMC article.

7

Fatal H7N9 pneumonia complicated by viral infection of a prosthetic cardiac valve - an autopsy study.

Nicholls JM, Tsai PN, Chan RW, Hui KP, Chan MC, Malik Peiris JS, Chan KH, Yuen KY, To KK. Nicholls JM, et al. J Clin Virol. 2014 Nov;61(3):466-9. doi: 10.1016/j.jcv.2014.08.005. Epub 2014 Aug 15. J Clin Virol. 2014. PMID: 25179790 No abstract available.

8

Modulation of sterol biosynthesis regulates viral replication and cytokine production in influenza A virus infected human alveolar epithelial cells.

Hui KP, Kuok DI, Kang SS, Li HS, Ng MM, Bui CH, Peiris JS, Chan RW, Chan MC. Hui KP, et al. Antiviral Res. 2015 Jul;119:1-7. doi: 10.1016/j.antiviral.2015.04.005. Epub 2015 Apr 13. Antiviral Res. 2015. PMID: 25882623

9

Human mesenchymal stromal cells reduce influenza A H5N1-associated acute lung injury in vitro and in vivo.

Chan MC, Kuok DI, Leung CY, Hui KP, Valkenburg SA, Lau EH, Nicholls JM, Fang X, Guan Y, Lee JW, Chan RW, Webster RG, Matthay MA, Peiris JS. Chan MC, et al. Proc Natl Acad Sci U S A. 2016 Mar 29;113(13):3621-6. doi: 10.1073/pnas.1601911113. Epub 2016 Mar 14. Proc Natl Acad Sci U S A. 2016. PMID: 26976597 Free PMC article.

10

Highly pathogenic avian influenza H5N1 virus delays apoptotic responses via activation of STAT3.

Hui KP, Li HS, Cheung MC, Chan RW, Yuen KM, Mok CK, Nicholls JM, Peiris JS, Chan MC. Hui KP, et al. Sci Rep. 2016 Jun 27;6:28593. doi: 10.1038/srep28593. Sci Rep. 2016. PMID: 27344974 Free PMC article.

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