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Regioselective Glycosylation Strategies for the Synthesis of Group Ia and Ib Streptococcus Related Glycans Enable Elucidating Unique Conformations of the Capsular Polysaccharides.
Del Bino L, Calloni I, Oldrini D, Raso MM, Cuffaro R, Ardá A, Codée JDC, Jiménez-Barbero J, Adamo R. Del Bino L, et al. Among authors: oldrini d. Chemistry. 2019 Dec 18;25(71):16277-16287. doi: 10.1002/chem.201903527. Epub 2019 Nov 4. Chemistry. 2019. PMID: 31506992 Free PMC article.
Combined Chemical Synthesis and Tailored Enzymatic Elongation Provide Fully Synthetic and Conjugation-Ready Neisseria meningitidis Serogroup X Vaccine Antigens.
Oldrini D, Fiebig T, Romano MR, Proietti D, Berger M, Tontini M, De Ricco R, Santini L, Morelli L, Lay L, Gerardy-Schahn R, Berti F, Adamo R. Oldrini D, et al. ACS Chem Biol. 2018 Apr 20;13(4):984-994. doi: 10.1021/acschembio.7b01057. Epub 2018 Mar 1. ACS Chem Biol. 2018. PMID: 29481045 Free article.
Structure of a protective epitope of group B Streptococcus type III capsular polysaccharide.
Carboni F, Adamo R, Fabbrini M, De Ricco R, Cattaneo V, Brogioni B, Veggi D, Pinto V, Passalacqua I, Oldrini D, Rappuoli R, Malito E, Margarit IYR, Berti F. Carboni F, et al. Among authors: oldrini d. Proc Natl Acad Sci U S A. 2017 May 9;114(19):5017-5022. doi: 10.1073/pnas.1701885114. Epub 2017 Apr 24. Proc Natl Acad Sci U S A. 2017. PMID: 28439022 Free PMC article.
Elucidating the Structural and Minimal Protective Epitope of the Serogroup X Meningococcal Capsular Polysaccharide.
Pietri GP, Tontini M, Brogioni B, Oldrini D, Robakiewicz S, Henriques P, Calloni I, Abramova V, Santini L, Malić S, Miklić K, Lisnic B, Bertuzzi S, Unione L, Balducci E, de Ruyck J, Romano MR, Jimenez-Barbero J, Bouckaert J, Jonjic S, Rovis TL, Adamo R. Pietri GP, et al. Among authors: oldrini d. Front Mol Biosci. 2021 Oct 14;8:745360. doi: 10.3389/fmolb.2021.745360. eCollection 2021. Front Mol Biosci. 2021. PMID: 34722634 Free PMC article.
Retaining the structural integrity of disulfide bonds in diphtheria toxoid carrier protein is crucial for the effectiveness of glycoconjugate vaccine candidates.
Carboni F, Kitowski A, Sorieul C, Veggi D, Marques MC, Oldrini D, Balducci E, Brogioni B, Del Bino L, Corrado A, Angiolini F, Dello Iacono L, Margarit I, Romano MR, Bernardes GJL, Adamo R. Carboni F, et al. Among authors: oldrini d. Chem Sci. 2022 Feb 10;13(8):2440-2449. doi: 10.1039/d1sc01928g. eCollection 2022 Feb 23. Chem Sci. 2022. PMID: 35310500 Free PMC article.
Oxetane Grafts Installed Site-Selectively on Native Disulfides to Enhance Protein Stability and Activity In Vivo.
Martínez-Sáez N, Sun S, Oldrini D, Sormanni P, Boutureira O, Carboni F, Compañón I, Deery MJ, Vendruscolo M, Corzana F, Adamo R, Bernardes GJL. Martínez-Sáez N, et al. Among authors: oldrini d. Angew Chem Int Ed Engl. 2017 Nov 20;56(47):14963-14967. doi: 10.1002/anie.201708847. Epub 2017 Oct 20. Angew Chem Int Ed Engl. 2017. PMID: 28968001 Free PMC article.
Generalized Modules for Membrane Antigens as Carrier for Polysaccharides: Impact of Sugar Length, Density, and Attachment Site on the Immune Response Elicited in Animal Models.
Micoli F, Alfini R, Di Benedetto R, Necchi F, Schiavo F, Mancini F, Carducci M, Oldrini D, Pitirollo O, Gasperini G, Balocchi C, Bechi N, Brunelli B, Piccioli D, Adamo R. Micoli F, et al. Among authors: oldrini d. Front Immunol. 2021 Sep 14;12:719315. doi: 10.3389/fimmu.2021.719315. eCollection 2021. Front Immunol. 2021. PMID: 34594333 Free PMC article.
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