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Once-weekly (70 mg/m2 ) vs twice-weekly (56 mg/m2 ) dosing of carfilzomib in patients with relapsed or refractory multiple myeloma: A post hoc analysis of the ENDEAVOR, A.R.R.O.W., and CHAMPION-1 trials.
Moreau P, Stewart KA, Dimopoulos M, Siegel D, Facon T, Berenson J, Raje N, Berdeja JG, Orlowski RZ, Yang H, Ma H, Klippel Z, Zahlten-Kumeli A, Mezzi K, Iskander K, Mateos MV. Moreau P, et al. Among authors: iskander k. Cancer Med. 2020 May;9(9):2989-2996. doi: 10.1002/cam4.2945. Epub 2020 Feb 28. Cancer Med. 2020. PMID: 32108443 Free PMC article.
Carfilzomib-dexamethasone versus subcutaneous or intravenous bortezomib in relapsed or refractory multiple myeloma: secondary analysis of the phase 3 ENDEAVOR study.
Goldschmidt H, Moreau P, Ludwig H, Niesvizky R, Chng WJ, Joshua D, Weisel K, Spencer A, Orlowski RZ, Feng S, Iskander KS, Dimopoulos MA. Goldschmidt H, et al. Among authors: iskander ks. Leuk Lymphoma. 2018 Jun;59(6):1364-1374. doi: 10.1080/10428194.2017.1376743. Epub 2017 Sep 22. Leuk Lymphoma. 2018. PMID: 28937327 Clinical Trial.
NRH:quinone oxidoreductase 2 and NAD(P)H:quinone oxidoreductase 1 protect tumor suppressor p53 against 20s proteasomal degradation leading to stabilization and activation of p53.
Gong X, Kole L, Iskander K, Jaiswal AK. Gong X, et al. Among authors: iskander k. Cancer Res. 2007 Jun 1;67(11):5380-8. doi: 10.1158/0008-5472.CAN-07-0323. Cancer Res. 2007. Retraction in: Cancer Res. 2015 Feb 1;75(3):615. doi: 10.1158/0008-5472.CAN-14-3458 PMID: 17545619 Retracted.
Carfilzomib as salvage therapy in Waldenstrom macroglobulinemia: a case series.
Vesole DH, Richter J, Biran N, McBride L, Anand P, Huang M, Kumeli AZ, Klippel Z, Iskander K, Siegel DS. Vesole DH, et al. Among authors: iskander k. Leuk Lymphoma. 2018 Jan;59(1):259-261. doi: 10.1080/10428194.2017.1321749. Epub 2017 Jun 5. Leuk Lymphoma. 2018. PMID: 28583038 No abstract available.
43 results