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Lactam-stabilized helical analogues of the analgesic μ-conotoxin KIIIA.
Khoo KK, Wilson MJ, Smith BJ, Zhang MM, Gulyas J, Yoshikami D, Rivier JE, Bulaj G, Norton RS. Khoo KK, et al. Among authors: smith bj. J Med Chem. 2011 Nov 10;54(21):7558-66. doi: 10.1021/jm200839a. Epub 2011 Oct 12. J Med Chem. 2011. PMID: 21962108 Free PMC article.
A minimized human insulin-receptor-binding motif revealed in a Conus geographus venom insulin.
Menting JG, Gajewiak J, MacRaild CA, Chou DH, Disotuar MM, Smith NA, Miller C, Erchegyi J, Rivier JE, Olivera BM, Forbes BE, Smith BJ, Norton RS, Safavi-Hemami H, Lawrence MC. Menting JG, et al. Among authors: smith bj, smith na. Nat Struct Mol Biol. 2016 Oct;23(10):916-920. doi: 10.1038/nsmb.3292. Epub 2016 Sep 12. Nat Struct Mol Biol. 2016. PMID: 27617429
A structurally minimized yet fully active insulin based on cone-snail venom insulin principles.
Xiong X, Menting JG, Disotuar MM, Smith NA, Delaine CA, Ghabash G, Agrawal R, Wang X, He X, Fisher SJ, MacRaild CA, Norton RS, Gajewiak J, Forbes BE, Smith BJ, Safavi-Hemami H, Olivera B, Lawrence MC, Chou DH. Xiong X, et al. Among authors: smith bj, smith na. Nat Struct Mol Biol. 2020 Jul;27(7):615-624. doi: 10.1038/s41594-020-0430-8. Epub 2020 Jun 1. Nat Struct Mol Biol. 2020. PMID: 32483339 Free PMC article.
Author Correction: A structurally minimized yet fully active insulin based on cone-snail venom insulin principles.
Xiong X, Menting JG, Disotuar MM, Smith NA, Delaine CA, Ghabash G, Agrawal R, Wang X, He X, Fisher SJ, MacRaild CA, Norton RS, Gajewiak J, Forbes BE, Smith BJ, Safavi-Hemami H, Olivera B, Lawrence MC, Chou DH. Xiong X, et al. Among authors: smith bj, smith na. Nat Struct Mol Biol. 2020 Jul;27(7):683. doi: 10.1038/s41594-020-0460-2. Nat Struct Mol Biol. 2020. PMID: 32533129
Determination of Protein-Ligand Binding Affinities by Thermal Shift Assay.
Khan MF, Rahman MM, Xin Y, Mustafa A, Smith BJ, Ottemann KM, Roujeinikova A. Khan MF, et al. Among authors: smith bj. ACS Pharmacol Transl Sci. 2024 Sep 17;7(10):3096-3107. doi: 10.1021/acsptsci.4c00293. eCollection 2024 Oct 11. ACS Pharmacol Transl Sci. 2024. PMID: 39430314
1,347 results