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Adipose triglyceride lipase activity regulates cancer cell proliferation via AMP-kinase and mTOR signaling.
Xie H, Heier C, Kien B, Vesely PW, Tang Z, Sexl V, Schoiswohl G, Strießnig-Bina I, Hoefler G, Zechner R, Schweiger M. Xie H, et al. Among authors: zechner r. Biochim Biophys Acta Mol Cell Biol Lipids. 2020 Sep;1865(9):158737. doi: 10.1016/j.bbalip.2020.158737. Epub 2020 May 11. Biochim Biophys Acta Mol Cell Biol Lipids. 2020. PMID: 32404277 Free PMC article.
Lipolysis of triglyceride-rich lipoproteins generates PPAR ligands: evidence for an antiinflammatory role for lipoprotein lipase.
Ziouzenkova O, Perrey S, Asatryan L, Hwang J, MacNaul KL, Moller DE, Rader DJ, Sevanian A, Zechner R, Hoefler G, Plutzky J. Ziouzenkova O, et al. Among authors: zechner r. Proc Natl Acad Sci U S A. 2003 Mar 4;100(5):2730-5. doi: 10.1073/pnas.0538015100. Epub 2003 Feb 26. Proc Natl Acad Sci U S A. 2003. PMID: 12606719 Free PMC article.
Fat mobilization in adipose tissue is promoted by adipose triglyceride lipase.
Zimmermann R, Strauss JG, Haemmerle G, Schoiswohl G, Birner-Gruenberger R, Riederer M, Lass A, Neuberger G, Eisenhaber F, Hermetter A, Zechner R. Zimmermann R, et al. Among authors: zechner r. Science. 2004 Nov 19;306(5700):1383-6. doi: 10.1126/science.1100747. Science. 2004. PMID: 15550674
Hepatic overexpression of hormone-sensitive lipase and adipose triglyceride lipase promotes fatty acid oxidation, stimulates direct release of free fatty acids, and ameliorates steatosis.
Reid BN, Ables GP, Otlivanchik OA, Schoiswohl G, Zechner R, Blaner WS, Goldberg IJ, Schwabe RF, Chua SC Jr, Huang LS. Reid BN, et al. Among authors: zechner r. J Biol Chem. 2008 May 9;283(19):13087-99. doi: 10.1074/jbc.M800533200. Epub 2008 Mar 12. J Biol Chem. 2008. PMID: 18337240 Free PMC article.
249 results