Zheng R - Search Results

1

Amelioration of an Inherited Metabolic Liver Disease through Creation of a De Novo Start Codon by Cytidine Base Editing.

Yang L, Wang L, Huo Y, Chen X, Yin S, Hu Y, Zhang X, Zheng R, Geng H, Han H, Ma X, Liu M, Li H, Yu W, Liu M, Wang J, Li D. Yang L, et al. Among authors: zheng r. Mol Ther. 2020 Jul 8;28(7):1673-1683. doi: 10.1016/j.ymthe.2020.05.001. Epub 2020 May 7. Mol Ther. 2020. PMID: 32413280 Free PMC article.

2

Increasing targeting scope of adenosine base editors in mouse and rat embryos through fusion of TadA deaminase with Cas9 variants.

Yang L, Zhang X, Wang L, Yin S, Zhu B, Xie L, Duan Q, Hu H, Zheng R, Wei Y, Peng L, Han H, Zhang J, Qiu W, Geng H, Siwko S, Zhang X, Liu M, Li D. Yang L, et al. Among authors: zheng r. Protein Cell. 2018 Sep;9(9):814-819. doi: 10.1007/s13238-018-0568-x. Protein Cell. 2018. PMID: 30066232 Free PMC article. No abstract available.

3

Generation of a Primary Hyperoxaluria Type 1 Disease Model Via CRISPR/Cas9 System in Rats.

Zheng R, Fang X, He L, Shao Y, Guo N, Wang L, Liu M, Li D, Geng H. Zheng R, et al. Curr Mol Med. 2018;18(7):436-447. doi: 10.2174/1566524019666181212092440. Curr Mol Med. 2018. PMID: 30539697

4

Correction to: Increasing targeting scope of adenosine base editors in mouse and rat embryos through fusion of TadA deaminase with Cas9 variants.

Yang L, Zhang X, Wang L, Yin S, Zhu B, Xie L, Duan Q, Hu H, Zheng R, Wei Y, Peng L, Han H, Zhang J, Qiu W, Geng H, Siwko S, Zhang X, Liu M, Li D. Yang L, et al. Among authors: zheng r. Protein Cell. 2019 Sep;10(9):700. doi: 10.1007/s13238-019-0631-2. Protein Cell. 2019. PMID: 31087276 Free PMC article.

5

CRISPR/Cas9-mediated metabolic pathway reprogramming in a novel humanized rat model ameliorates primary hyperoxaluria type 1.

Zheng R, Li Y, Wang L, Fang X, Zhang J, He L, Yang L, Li D, Geng H. Zheng R, et al. Kidney Int. 2020 Oct;98(4):947-957. doi: 10.1016/j.kint.2020.04.049. Epub 2020 May 25. Kidney Int. 2020. PMID: 32464217 Free article.

6

Knockdown of lactate dehydrogenase by adeno-associated virus-delivered CRISPR/Cas9 system alleviates primary hyperoxaluria type 1.

Zheng R, Fang X, Chen X, Huang Y, Xu G, He L, Li Y, Niu X, Yang L, Wang L, Li D, Geng H. Zheng R, et al. Clin Transl Med. 2020 Dec;10(8):e261. doi: 10.1002/ctm2.261. Clin Transl Med. 2020. PMID: 33377632 Free PMC article.

7

Generation and characterization of a novel rat model of primary hyperoxaluria type 1 with a nonsense mutation in alanine-glyoxylate aminotransferase gene.

Li Y, Zheng R, Xu G, Huang Y, Li Y, Li D, Geng H. Li Y, et al. Among authors: zheng r. Am J Physiol Renal Physiol. 2021 Mar 1;320(3):F475-F484. doi: 10.1152/ajprenal.00514.2020. Epub 2021 Jan 25. Am J Physiol Renal Physiol. 2021. PMID: 33491567 Free article.

8

Differences in renal cortex transcriptional profiling of wild-type and novel type B cystinuria model rats.

Zhang Z, Zheng R, Chen Z, Zhan X, Fang X, Liu M, Li Y, Xu Y, Li D, Geng H, Zhang X, Xu G. Zhang Z, et al. Among authors: zheng r. Urolithiasis. 2022 Jun;50(3):279-291. doi: 10.1007/s00240-022-01321-6. Epub 2022 Apr 13. Urolithiasis. 2022. PMID: 35416493 Free PMC article.

9

Lipidomics characterization of the lipid metabolism profiles in a cystinuria rat model: Precalculus damage in the kidney of cystinuria.

Zhang Z, Zheng R, Zhu C, Geng H, Xu G. Zhang Z, et al. Among authors: zheng r. Prostaglandins Other Lipid Mediat. 2022 Oct;162:106651. doi: 10.1016/j.prostaglandins.2022.106651. Epub 2022 Jun 6. Prostaglandins Other Lipid Mediat. 2022. PMID: 35680078

10

Multiplex gene editing reduces oxalate production in primary hyperoxaluria type 1.

Zheng R, Zhang DX, Shao YJ, Fang XL, Yang L, Huo YN, Li DL, Geng HQ. Zheng R, et al. Zool Res. 2023 Nov 18;44(6):993-1002. doi: 10.24272/j.issn.2095-8137.2022.495. Zool Res. 2023. PMID: 37759334 Free PMC article.

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