Shinkai Y - Search Results

1

Repression of mercury accumulation and adverse effects of methylmercury exposure is mediated by cystathionine γ-lyase to produce reactive sulfur species in mouse brain.

Akiyama M, Unoki T, Yoshida E, Ding Y, Yamakawa H, Shinkai Y, Ishii I, Kumagai Y. Akiyama M, et al. Among authors: shinkai y. Toxicol Lett. 2020 May 13;330:128-133. doi: 10.1016/j.toxlet.2020.05.007. Online ahead of print. Toxicol Lett. 2020. PMID: 32413476

2

Sulforaphane, an activator of Nrf2, suppresses cellular accumulation of arsenic and its cytotoxicity in primary mouse hepatocytes.

Shinkai Y, Sumi D, Fukami I, Ishii T, Kumagai Y. Shinkai Y, et al. FEBS Lett. 2006 Mar 20;580(7):1771-4. doi: 10.1016/j.febslet.2006.02.031. Epub 2006 Feb 24. FEBS Lett. 2006. PMID: 16516206 Free article.

3

Activation of the Nrf2 pathway, but decreased gamma-glutamylcysteine synthetase heavy subunit chain levels and caspase-3-dependent apoptosis during exposure of primary mouse hepatocytes to diphenylarsinic acid.

Sumi D, Manji A, Shinkai Y, Toyama T, Kumagai Y. Sumi D, et al. Among authors: shinkai y. Toxicol Appl Pharmacol. 2007 Sep 15;223(3):218-24. doi: 10.1016/j.taap.2007.06.001. Epub 2007 Jun 18. Toxicol Appl Pharmacol. 2007. PMID: 17628625

4

Cytoprotective role of Nrf2/Keap1 system in methylmercury toxicity.

Toyama T, Sumi D, Shinkai Y, Yasutake A, Taguchi K, Tong KI, Yamamoto M, Kumagai Y. Toyama T, et al. Among authors: shinkai y. Biochem Biophys Res Commun. 2007 Nov 23;363(3):645-50. doi: 10.1016/j.bbrc.2007.09.017. Epub 2007 Sep 18. Biochem Biophys Res Commun. 2007. PMID: 17904103

5

Dysfunction of Nrf2 decreases KBrO3-induced oxidative DNA damage in Ogg1-null mice.

Jałoszyński P, Murata S, Shinkai Y, Takahashi S, Kumagai Y, Nishimura S, Yamamoto M. Jałoszyński P, et al. Among authors: shinkai y. Biochem Biophys Res Commun. 2007 Dec 28;364(4):966-71. doi: 10.1016/j.bbrc.2007.10.123. Epub 2007 Oct 29. Biochem Biophys Res Commun. 2007. PMID: 17971305 Free article.

6

Role of aquaporin 9 in cellular accumulation of arsenic and its cytotoxicity in primary mouse hepatocytes.

Shinkai Y, Sumi D, Toyama T, Kaji T, Kumagai Y. Shinkai Y, et al. Toxicol Appl Pharmacol. 2009 Jun 1;237(2):232-6. doi: 10.1016/j.taap.2009.03.014. Epub 2009 Mar 31. Toxicol Appl Pharmacol. 2009. PMID: 19341753

7

Signal transduction pathways and transcription factors triggered by arsenic trioxide in leukemia cells.

Sumi D, Shinkai Y, Kumagai Y. Sumi D, et al. Among authors: shinkai y. Toxicol Appl Pharmacol. 2010 May 1;244(3):385-92. doi: 10.1016/j.taap.2010.02.012. Epub 2010 Mar 1. Toxicol Appl Pharmacol. 2010. PMID: 20193703 Review.

8

Reduction of arsenic-induced cytotoxicity through Nrf2/HO-1 signaling in HepG2 cells.

Abiko Y, Shinkai Y, Sumi D, Kumagai Y. Abiko Y, et al. Among authors: shinkai y. J Toxicol Sci. 2010 Jun;35(3):419-23. doi: 10.2131/jts.35.419. J Toxicol Sci. 2010. PMID: 20519851 Free article.

9

Carbon monoxide derived from heme oxygenase-2 mediates reduction of methylmercury toxicity in SH-SY5Y cells.

Toyama T, Shinkai Y, Sumi D, Kumagai Y. Toyama T, et al. Among authors: shinkai y. Toxicol Appl Pharmacol. 2010 Nov 15;249(1):86-90. doi: 10.1016/j.taap.2010.08.021. Epub 2010 Aug 31. Toxicol Appl Pharmacol. 2010. PMID: 20807546

10

Isothiocyanates reduce mercury accumulation via an Nrf2-dependent mechanism during exposure of mice to methylmercury.

Toyama T, Shinkai Y, Yasutake A, Uchida K, Yamamoto M, Kumagai Y. Toyama T, et al. Among authors: shinkai y. Environ Health Perspect. 2011 Aug;119(8):1117-22. doi: 10.1289/ehp.1003123. Epub 2011 Mar 7. Environ Health Perspect. 2011. PMID: 21382770 Free PMC article.

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