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ACLY is the novel signaling target of PIP2/PIP3 and Lyn in acute myeloid leukemia.
Basappa J, Citir M, Zhang Q, Wang HY, Liu X, Melnikov O, Yahya H, Stein F, Muller R, Traynor-Kaplan A, Schultz C, Wasik MA, Ptasznik A. Basappa J, et al. Among authors: traynor kaplan a. Heliyon. 2020 May 7;6(5):e03910. doi: 10.1016/j.heliyon.2020.e03910. eCollection 2020 May. Heliyon. 2020. PMID: 32420483 Free PMC article.
PIP₃ induces the recycling of receptor tyrosine kinases.
Laketa V, Zarbakhsh S, Traynor-Kaplan A, Macnamara A, Subramanian D, Putyrski M, Mueller R, Nadler A, Mentel M, Saez-Rodriguez J, Pepperkok R, Schultz C. Laketa V, et al. Sci Signal. 2014 Jan 14;7(308):ra5. doi: 10.1126/scisignal.2004532. Sci Signal. 2014. PMID: 24425787
D-myo-Inositol 1,4,5,6-tetrakisphosphate produced in human intestinal epithelial cells in response to Salmonella invasion inhibits phosphoinositide 3-kinase signaling pathways.
Eckmann L, Rudolf MT, Ptasznik A, Schultz C, Jiang T, Wolfson N, Tsien R, Fierer J, Shears SB, Kagnoff MF, Traynor-Kaplan AE. Eckmann L, et al. Proc Natl Acad Sci U S A. 1997 Dec 23;94(26):14456-60. doi: 10.1073/pnas.94.26.14456. Proc Natl Acad Sci U S A. 1997. PMID: 9405634 Free PMC article.
54 results