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Clinical Protocol for a Longitudinal Cohort Study Employing Systems Biology to Identify Markers of Vaccine Immunogenicity in Newborn Infants in The Gambia and Papua New Guinea.
Idoko OT, Smolen KK, Wariri O, Imam A, Shannon CP, Dibassey T, Diray-Arce J, Darboe A, Strandmark J, Ben-Othman R, Odumade OA, McEnaney K, Amenyogbe N, Pomat WS, van Haren S, Sanchez-Schmitz G, Brinkman RR, Steen H, Hancock REW, Tebbutt SJ, Richmond PC, van den Biggelaar AHJ, Kollmann TR, Levy O, Ozonoff A, Kampmann B. Idoko OT, et al. Among authors: van haren s, van den biggelaar ahj. Front Pediatr. 2020 Apr 30;8:197. doi: 10.3389/fped.2020.00197. eCollection 2020. Front Pediatr. 2020. PMID: 32426309 Free PMC article.
Soluble mediators regulating immunity in early life.
Pettengill MA, van Haren SD, Levy O. Pettengill MA, et al. Front Immunol. 2014 Sep 24;5:457. doi: 10.3389/fimmu.2014.00457. eCollection 2014. Front Immunol. 2014. PMID: 25309541 Free PMC article. Review.
The Imidazoquinoline Toll-Like Receptor-7/8 Agonist Hybrid-2 Potently Induces Cytokine Production by Human Newborn and Adult Leukocytes.
Ganapathi L, Van Haren S, Dowling DJ, Bergelson I, Shukla NM, Malladi SS, Balakrishna R, Tanji H, Ohto U, Shimizu T, David SA, Levy O. Ganapathi L, et al. Among authors: van haren s. PLoS One. 2015 Aug 14;10(8):e0134640. doi: 10.1371/journal.pone.0134640. eCollection 2015. PLoS One. 2015. PMID: 26274907 Free PMC article.
A Meningococcal Outer Membrane Vesicle Vaccine Incorporating Genetically Attenuated Endotoxin Dissociates Inflammation from Immunogenicity.
Dowling DJ, Sanders H, Cheng WK, Joshi S, Brightman S, Bergelson I, Pietrasanta C, van Haren SD, van Amsterdam S, Fernandez J, van den Dobbelsteen GP, Levy O. Dowling DJ, et al. Among authors: van amsterdam s, van den dobbelsteen gp, van haren sd. Front Immunol. 2016 Dec 8;7:562. doi: 10.3389/fimmu.2016.00562. eCollection 2016. Front Immunol. 2016. PMID: 28008331 Free PMC article.
Toll-like receptor 8 agonist nanoparticles mimic immunomodulating effects of the live BCG vaccine and enhance neonatal innate and adaptive immune responses.
Dowling DJ, Scott EA, Scheid A, Bergelson I, Joshi S, Pietrasanta C, Brightman S, Sanchez-Schmitz G, Van Haren SD, Ninković J, Kats D, Guiducci C, de Titta A, Bonner DK, Hirosue S, Swartz MA, Hubbell JA, Levy O. Dowling DJ, et al. Among authors: van haren sd. J Allergy Clin Immunol. 2017 Nov;140(5):1339-1350. doi: 10.1016/j.jaci.2016.12.985. Epub 2017 Mar 23. J Allergy Clin Immunol. 2017. PMID: 28343701 Free PMC article.
TLR7/8 adjuvant overcomes newborn hyporesponsiveness to pneumococcal conjugate vaccine at birth.
Dowling DJ, van Haren SD, Scheid A, Bergelson I, Kim D, Mancuso CJ, Foppen W, Ozonoff A, Fresh L, Theriot TB, Lackner AA, Fichorova RN, Smirnov D, Vasilakos JP, Beaurline JM, Tomai MA, Midkiff CC, Alvarez X, Blanchard JL, Gilbert MH, Aye PP, Levy O. Dowling DJ, et al. JCI Insight. 2017 Mar 23;2(6):e91020. doi: 10.1172/jci.insight.91020. JCI Insight. 2017. PMID: 28352660 Free PMC article.
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