Fischer CR - Search Results

1

Enhancing the Antiviral Efficacy of RNA-Dependent RNA Polymerase Inhibition by Combination with Modulators of Pyrimidine Metabolism.

Liu Q, Gupta A, Okesli-Armlovich A, Qiao W, Fischer CR, Smith M, Carette JE, Bassik MC, Khosla C. Liu Q, et al. Among authors: fischer cr. Cell Chem Biol. 2020 Jun 18;27(6):668-677.e9. doi: 10.1016/j.chembiol.2020.05.002. Epub 2020 May 21. Cell Chem Biol. 2020. PMID: 32442424 Free PMC article.

2

Heterologous expression of diverse propionyl-CoA carboxylases affects polyketide production in Escherichia coli.

Vandova GA, O'Brien RV, Lowry B, Robbins TF, Fischer CR, Davis RW, Khosla C, Harvey CJ, Hillenmeyer ME. Vandova GA, et al. Among authors: fischer cr. J Antibiot (Tokyo). 2017 Jul;70(7):859-863. doi: 10.1038/ja.2017.38. Epub 2017 Apr 12. J Antibiot (Tokyo). 2017. PMID: 28400575 Free PMC article. No abstract available.

3

Genetic Mapping and Biochemical Basis of Yellow Feather Pigmentation in Budgerigars.

Cooke TF, Fischer CR, Wu P, Jiang TX, Xie KT, Kuo J, Doctorov E, Zehnder A, Khosla C, Chuong CM, Bustamante CD. Cooke TF, et al. Among authors: fischer cr. Cell. 2017 Oct 5;171(2):427-439.e21. doi: 10.1016/j.cell.2017.08.016. Cell. 2017. PMID: 28985565 Free PMC article.

4

HEx: A heterologous expression platform for the discovery of fungal natural products.

Harvey CJB, Tang M, Schlecht U, Horecka J, Fischer CR, Lin HC, Li J, Naughton B, Cherry J, Miranda M, Li YF, Chu AM, Hennessy JR, Vandova GA, Inglis D, Aiyar RS, Steinmetz LM, Davis RW, Medema MH, Sattely E, Khosla C, St Onge RP, Tang Y, Hillenmeyer ME. Harvey CJB, et al. Among authors: fischer cr. Sci Adv. 2018 Apr 11;4(4):eaar5459. doi: 10.1126/sciadv.aar5459. eCollection 2018 Apr. Sci Adv. 2018. PMID: 29651464 Free PMC article.

5

Tunable Enzymatic Synthesis of the Immunomodulator Lipid IV_A To Enable Structure-Activity Analysis.

Sankaranarayanan K, Antaris XX, Palanski BA, El Gamal A, Kao CM, Fitch WL, Fischer CR, Khosla C. Sankaranarayanan K, et al. Among authors: fischer cr. J Am Chem Soc. 2019 Jun 19;141(24):9474-9478. doi: 10.1021/jacs.9b03066. Epub 2019 Jun 11. J Am Chem Soc. 2019. PMID: 31184877 Free PMC article.

6

CRISPR-Cas9 screens identify regulators of antibody-drug conjugate toxicity.

Tsui CK, Barfield RM, Fischer CR, Morgens DW, Li A, Smith BAH, Gray MA, Bertozzi CR, Rabuka D, Bassik MC. Tsui CK, et al. Among authors: fischer cr. Nat Chem Biol. 2019 Oct;15(10):949-958. doi: 10.1038/s41589-019-0342-2. Epub 2019 Aug 26. Nat Chem Biol. 2019. PMID: 31451760 Free PMC article.

7

Family-wide Annotation of Enzymatic Pathways by Parallel In Vivo Metabolomics.

Kim JT, Li VL, Terrell SM, Fischer CR, Long JZ. Kim JT, et al. Among authors: fischer cr. Cell Chem Biol. 2019 Nov 21;26(11):1623-1629.e3. doi: 10.1016/j.chembiol.2019.09.009. Epub 2019 Oct 3. Cell Chem Biol. 2019. PMID: 31587987 Free PMC article.

8

Complete Reconstitution and Deorphanization of the 3 MDa Nocardiosis-Associated Polyketide Synthase.

Yuet KP, Liu CW, Lynch SR, Kuo J, Michaels W, Lee RB, McShane AE, Zhong BL, Fischer CR, Khosla C. Yuet KP, et al. Among authors: fischer cr. J Am Chem Soc. 2020 Apr 1;142(13):5952-5957. doi: 10.1021/jacs.0c00904. Epub 2020 Mar 20. J Am Chem Soc. 2020. PMID: 32182063 Free PMC article.

9

A Plasma Protein Network Regulates PM20D1 and N-Acyl Amino Acid Bioactivity.

Kim JT, Jedrychowski MP, Wei W, Fernandez D, Fischer CR, Banik SM, Spiegelman BM, Long JZ. Kim JT, et al. Among authors: fischer cr. Cell Chem Biol. 2020 Sep 17;27(9):1130-1139.e4. doi: 10.1016/j.chembiol.2020.04.009. Epub 2020 May 12. Cell Chem Biol. 2020. PMID: 32402239 Free PMC article.

10

A Metabolic Pathway for Activation of Dietary Glucosinolates by a Human Gut Symbiont.

Liou CS, Sirk SJ, Diaz CAC, Klein AP, Fischer CR, Higginbottom SK, Erez A, Donia MS, Sonnenburg JL, Sattely ES. Liou CS, et al. Among authors: fischer cr. Cell. 2020 Feb 20;180(4):717-728.e19. doi: 10.1016/j.cell.2020.01.023. Cell. 2020. PMID: 32084341 Free PMC article.

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