Munier-Lehmann H - Search Results

1

A real-time cell-binding assay reveals dynamic features of STxB-Gb3 cointernalization and STxB-mediated cargo delivery into cancer cells.

Encarnação JC, Napolitano V, Opassi G, Danielson UH, Dubin G, Popowicz GM, Munier-Lehmann H, Buijs J, Andersson K, Björkelund H. Encarnação JC, et al. FEBS Lett. 2020 Aug;594(15):2406-2420. doi: 10.1002/1873-3468.13847. Epub 2020 Jun 23. FEBS Lett. 2020. PMID: 32473599 Free article.

2

Structural basis for the allosteric inhibition of UMP kinase from Gram-positive bacteria, a promising antibacterial target.

Walter P, Mechaly A, Bous J, Haouz A, England P, Lai-Kee-Him J, Ancelin A, Hoos S, Baron B, Trapani S, Bron P, Labesse G, Munier-Lehmann H. Walter P, et al. FEBS J. 2022 Aug;289(16):4869-4887. doi: 10.1111/febs.16393. Epub 2022 Mar 9. FEBS J. 2022. PMID: 35152545 Free article.

3

Interaction network among de novo purine nucleotide biosynthesis enzymes in Escherichia coli.

Gedeon A, Karimova G, Ayoub N, Dairou J, Giai Gianetto Q, Vichier-Guerre S, Vidalain PO, Ladant D, Munier-Lehmann H. Gedeon A, et al. Among authors: munier lehmann h. FEBS J. 2023 Jun;290(12):3165-3184. doi: 10.1111/febs.16746. Epub 2023 Mar 3. FEBS J. 2023. PMID: 36748301 Free article.

4

Thymidylate kinase of Mycobacterium tuberculosis: a chimera sharing properties common to eukaryotic and bacterial enzymes.

Munier-Lehmann H, Chaffotte A, Pochet S, Labesse G. Munier-Lehmann H, et al. Protein Sci. 2001 Jun;10(6):1195-205. doi: 10.1110/ps.45701. Protein Sci. 2001. PMID: 11369858 Free PMC article.

5

Enzymatic and structural analysis of inhibitors designed against Mycobacterium tuberculosis thymidylate kinase. New insights into the phosphoryl transfer mechanism.

Haouz A, Vanheusden V, Munier-Lehmann H, Froeyen M, Herdewijn P, Van Calenbergh S, Delarue M. Haouz A, et al. J Biol Chem. 2003 Feb 14;278(7):4963-71. doi: 10.1074/jbc.M209630200. Epub 2002 Nov 25. J Biol Chem. 2003. PMID: 12454011 Free article.

6

Mycobacterium tuberculosis thymidylate kinase: structural studies of intermediates along the reaction pathway.

Fioravanti E, Haouz A, Ursby T, Munier-Lehmann H, Delarue M, Bourgeois D. Fioravanti E, et al. J Mol Biol. 2003 Apr 11;327(5):1077-92. doi: 10.1016/s0022-2836(03)00202-x. J Mol Biol. 2003. PMID: 12662932

7

Comparative study of purine and pyrimidine nucleoside analogues acting on the thymidylate kinases of Mycobacterium tuberculosis and of humans.

Pochet S, Dugué L, Labesse G, Delepierre M, Munier-Lehmann H. Pochet S, et al. Chembiochem. 2003 Aug 4;4(8):742-7. doi: 10.1002/cbic.200300608. Chembiochem. 2003. PMID: 12898625

8

Design of Mycobacterium tuberculosis thymidine monophosphate kinase inhibitors.

Munier-Lehmann H, Pochet S, Dugue L, Dutruel O, Labesse G, Douget D. Munier-Lehmann H, et al. Nucleosides Nucleotides Nucleic Acids. 2003 May-Aug;22(5-8):801-4. doi: 10.1081/NCN-120022638. Nucleosides Nucleotides Nucleic Acids. 2003. PMID: 14565282 No abstract available.

9

LEA3D: a computer-aided ligand design for structure-based drug design.

Douguet D, Munier-Lehmann H, Labesse G, Pochet S. Douguet D, et al. J Med Chem. 2005 Apr 7;48(7):2457-68. doi: 10.1021/jm0492296. J Med Chem. 2005. PMID: 15801836

10

The crystal structure of Mycobacterium tuberculosis adenylate kinase in complex with two molecules of ADP and Mg2+ supports an associative mechanism for phosphoryl transfer.

Bellinzoni M, Haouz A, Graña M, Munier-Lehmann H, Shepard W, Alzari PM. Bellinzoni M, et al. Protein Sci. 2006 Jun;15(6):1489-93. doi: 10.1110/ps.062163406. Epub 2006 May 2. Protein Sci. 2006. PMID: 16672241 Free PMC article.

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