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T1D progression is associated with loss of CD3+CD56+ regulatory T cells that control CD8+ T cell effector functions.
Terrazzano G, Bruzzaniti S, Rubino V, Santopaolo M, Palatucci AT, Giovazzino A, La Rocca C, de Candia P, Puca A, Perna F, Procaccini C, De Rosa V, Porcellini C, De Simone S, Fattorusso V, Porcellini A, Mozzillo E, Troncone R, Franzese A, Ludvigsson J, Matarese G, Ruggiero G, Galgani M. Terrazzano G, et al. Among authors: de rosa v, de simone s, de candia p. Nat Metab. 2020 Feb;2(2):142-152. doi: 10.1038/s42255-020-0173-1. Epub 2020 Feb 17. Nat Metab. 2020. PMID: 32500117 Free PMC article.
Glycolysis controls the induction of human regulatory T cells by modulating the expression of FOXP3 exon 2 splicing variants.
De Rosa V, Galgani M, Porcellini A, Colamatteo A, Santopaolo M, Zuchegna C, Romano A, De Simone S, Procaccini C, La Rocca C, Carrieri PB, Maniscalco GT, Salvetti M, Buscarinu MC, Franzese A, Mozzillo E, La Cava A, Matarese G. De Rosa V, et al. Among authors: de simone s. Nat Immunol. 2015 Nov;16(11):1174-84. doi: 10.1038/ni.3269. Epub 2015 Sep 28. Nat Immunol. 2015. PMID: 26414764 Free PMC article.
An immunometabolic pathomechanism for chronic obstructive pulmonary disease.
Bruzzaniti S, Bocchino M, Santopaolo M, Calì G, Stanziola AA, D'Amato M, Esposito A, Barra E, Garziano F, Micillo T, Zuchegna C, Romano A, De Simone S, Zuccarelli B, Mottola M, De Rosa V, Porcellini A, Perna F, Matarese G, Galgani M. Bruzzaniti S, et al. Among authors: de simone s, de rosa v. Proc Natl Acad Sci U S A. 2019 Jul 30;116(31):15625-15634. doi: 10.1073/pnas.1906303116. Epub 2019 Jul 15. Proc Natl Acad Sci U S A. 2019. PMID: 31308239 Free PMC article.
Deciphering the role of protein kinase A in the control of FoxP3 expression in regulatory T cells in health and autoimmunity.
Lepore MT, Bruzzaniti S, La Rocca C, Fusco C, Carbone F, Mottola M, Zuccarelli B, Lanzillo R, Brescia Morra V, Maniscalco GT, De Simone S, Procaccini C, Porcellini A, De Rosa V, Galgani M, Cassano S, Matarese G. Lepore MT, et al. Among authors: de simone s, de rosa v. Sci Rep. 2024 Jul 30;14(1):17571. doi: 10.1038/s41598-024-68098-z. Sci Rep. 2024. PMID: 39080325 Free PMC article.
217 results