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ALS/FTD mutations in UBQLN2 impede autophagy by reducing autophagosome acidification through loss of function.
Wu JJ, Cai A, Greenslade JE, Higgins NR, Fan C, Le NTT, Tatman M, Whiteley AM, Prado MA, Dieriks BV, Curtis MA, Shaw CE, Siddique T, Faull RLM, Scotter EL, Finley D, Monteiro MJ. Wu JJ, et al. Among authors: prado ma. Proc Natl Acad Sci U S A. 2020 Jun 30;117(26):15230-15241. doi: 10.1073/pnas.1917371117. Epub 2020 Jun 8. Proc Natl Acad Sci U S A. 2020. PMID: 32513711 Free PMC article.
Highly Multiplexed Quantitative Mass Spectrometry Analysis of Ubiquitylomes.
Rose CM, Isasa M, Ordureau A, Prado MA, Beausoleil SA, Jedrychowski MP, Finley DJ, Harper JW, Gygi SP. Rose CM, et al. Among authors: prado ma. Cell Syst. 2016 Oct 26;3(4):395-403.e4. doi: 10.1016/j.cels.2016.08.009. Epub 2016 Sep 22. Cell Syst. 2016. PMID: 27667366 Free PMC article.
The Proteasome and Its Network: Engineering for Adaptability.
Finley D, Prado MA. Finley D, et al. Among authors: prado ma. Cold Spring Harb Perspect Biol. 2020 Jan 2;12(1):a033985. doi: 10.1101/cshperspect.a033985. Cold Spring Harb Perspect Biol. 2020. PMID: 30833452 Free PMC article. Review.
Global proteomics of Ubqln2-based murine models of ALS.
Whiteley AM, Prado MA, de Poot SAH, Paulo JA, Ashton M, Dominguez S, Weber M, Ngu H, Szpyt J, Jedrychowski MP, Easton A, Gygi SP, Kurz T, Monteiro MJ, Brown EJ, Finley D. Whiteley AM, et al. Among authors: prado ma. J Biol Chem. 2021 Jan-Jun;296:100153. doi: 10.1074/jbc.RA120.015960. Epub 2020 Dec 10. J Biol Chem. 2021. PMID: 33277362 Free PMC article.
296 results