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AP-1 imprints a reversible transcriptional programme of senescent cells.
Martínez-Zamudio RI, Roux PF, de Freitas JANLF, Robinson L, Doré G, Sun B, Belenki D, Milanovic M, Herbig U, Schmitt CA, Gil J, Bischof O. Martínez-Zamudio RI, et al. Among authors: schmitt ca. Nat Cell Biol. 2020 Jul;22(7):842-855. doi: 10.1038/s41556-020-0529-5. Epub 2020 Jun 8. Nat Cell Biol. 2020. PMID: 32514071 Free PMC article.
Oncogene-induced senescence as an initial barrier in lymphoma development.
Braig M, Lee S, Loddenkemper C, Rudolph C, Peters AH, Schlegelberger B, Stein H, Dörken B, Jenuwein T, Schmitt CA. Braig M, et al. Among authors: schmitt ca. Nature. 2005 Aug 4;436(7051):660-5. doi: 10.1038/nature03841. Nature. 2005. PMID: 16079837 Free article.
Synthetic lethal metabolic targeting of cellular senescence in cancer therapy.
Dörr JR, Yu Y, Milanovic M, Beuster G, Zasada C, Däbritz JH, Lisec J, Lenze D, Gerhardt A, Schleicher K, Kratzat S, Purfürst B, Walenta S, Mueller-Klieser W, Gräler M, Hummel M, Keller U, Buck AK, Dörken B, Willmitzer L, Reimann M, Kempa S, Lee S, Schmitt CA. Dörr JR, et al. Among authors: schmitt ca. Nature. 2013 Sep 19;501(7467):421-5. doi: 10.1038/nature12437. Epub 2013 Aug 14. Nature. 2013. PMID: 23945590
CD20-Targeting Immunotherapy Promotes Cellular Senescence in B-Cell Lymphoma.
Däbritz JH, Yu Y, Milanovic M, Schönlein M, Rosenfeldt MT, Dörr JR, Kaufmann AM, Dörken B, Schmitt CA. Däbritz JH, et al. Among authors: schmitt ca. Mol Cancer Ther. 2016 May;15(5):1074-81. doi: 10.1158/1535-7163.MCT-15-0627. Epub 2016 Feb 15. Mol Cancer Ther. 2016. PMID: 26880268
Pharmacological restoration and therapeutic targeting of the B-cell phenotype in classical Hodgkin lymphoma.
Du J, Neuenschwander M, Yu Y, Däbritz JH, Neuendorff NR, Schleich K, Bittner A, Milanovic M, Beuster G, Radetzki S, Specker E, Reimann M, Rosenbauer F, Mathas S, Lohneis P, Hummel M, Dörken B, von Kries JP, Lee S, Schmitt CA. Du J, et al. Among authors: schmitt ca. Blood. 2017 Jan 5;129(1):71-81. doi: 10.1182/blood-2016-02-700773. Epub 2016 Oct 12. Blood. 2017. PMID: 27733358 Free article.
Senescence-associated reprogramming promotes cancer stemness.
Milanovic M, Fan DNY, Belenki D, Däbritz JHM, Zhao Z, Yu Y, Dörr JR, Dimitrova L, Lenze D, Monteiro Barbosa IA, Mendoza-Parra MA, Kanashova T, Metzner M, Pardon K, Reimann M, Trumpp A, Dörken B, Zuber J, Gronemeyer H, Hummel M, Dittmar G, Lee S, Schmitt CA. Milanovic M, et al. Among authors: schmitt ca. Nature. 2018 Jan 4;553(7686):96-100. doi: 10.1038/nature25167. Epub 2017 Dec 20. Nature. 2018. PMID: 29258294
The dynamic nature of senescence in cancer.
Lee S, Schmitt CA. Lee S, et al. Among authors: schmitt ca. Nat Cell Biol. 2019 Jan;21(1):94-101. doi: 10.1038/s41556-018-0249-2. Epub 2019 Jan 2. Nat Cell Biol. 2019. PMID: 30602768 Review.
165 results