Lu Y - Search Results

1

A novel M phase blocker, DCZ3301 enhances the sensitivity of bortezomib in resistant multiple myeloma through DNA damage and mitotic catastrophe.

Hu L, Li B, Chen G, Song D, Xu Z, Gao L, Xi M, Zhou J, Li L, Zhang H, Feng Q, Wang Y, Lu K, Lu Y, Bu W, Wang H, Wu X, Zhu W, Shi J. Hu L, et al. Among authors: lu y, lu k. J Exp Clin Cancer Res. 2020 Jun 9;39(1):105. doi: 10.1186/s13046-020-01597-9. J Exp Clin Cancer Res. 2020. PMID: 32517809 Free PMC article.

2

Anti-DLBCL efficacy of DCZ0825 in vitro and in vivo: involvement of the PI3K‒AKT‒mTOR/JNK pathway.

Hu K, Li B, Ma R, Yi H, Xu Z, Peng Y, Yu D, Wu H, Cheng T, Lu Y, Zhang Y, Wei R, Yang G, Wu X, Zhu W, Shi J. Hu K, et al. Among authors: lu y. Acta Biochim Biophys Sin (Shanghai). 2021 Apr 15;53(5):575-583. doi: 10.1093/abbs/gmab031. Acta Biochim Biophys Sin (Shanghai). 2021. PMID: 33821934 Free article.

3

DCZ0014, a novel compound in the therapy of diffuse large B-cell lymphoma via the B cell receptor signaling pathway.

Chang S, Li B, Xie Y, Wang Y, Xu Z, Jin S, Yu D, Wang H, Lu Y, Zhang Y, Ma R, Huang C, Lai W, Wu X, Zhu W, Shi J. Chang S, et al. Among authors: lu y. Neoplasia. 2022 Jan;24(1):50-61. doi: 10.1016/j.neo.2021.12.001. Epub 2021 Dec 7. Neoplasia. 2022. PMID: 34890905 Free PMC article.

4

Preclinical validation and phase I trial of 4-hydroxysalicylanilide, targeting ribonucleotide reductase mediated dNTP synthesis in multiple myeloma.

Xie Y, Wang Y, Xu Z, Lu Y, Song D, Gao L, Yu D, Li B, Chen G, Zhang H, Feng Q, Zhang Y, Hu K, Huang C, Peng Y, Wu X, Mao Z, Shao J, Zhu W, Shi J. Xie Y, et al. Among authors: lu y. J Biomed Sci. 2022 May 12;29(1):32. doi: 10.1186/s12929-022-00813-2. J Biomed Sci. 2022. PMID: 35546402 Free PMC article. Clinical Trial.

5

Aberrant activation of TRIP13-EZH2 signaling axis promotes stemness and therapy resistance in multiple myeloma.

Xu L, Wang Y, Wang G, Guo S, Yu D, Feng Q, Hu K, Chen G, Li B, Xu Z, Jia X, Lu Y, Zhang H, Gao X, Chang S, Wang H, Wu X, Song D, Yang G, Zhu H, Zhou J, Zhan F, Zhu W, Shi J. Xu L, et al. Among authors: lu y. Leukemia. 2023 Jul;37(7):1576-1579. doi: 10.1038/s41375-023-01925-w. Epub 2023 May 8. Leukemia. 2023. PMID: 37157015 No abstract available.

6

Ribosomal protein S3 mediates drug resistance of proteasome inhibitor: potential therapeutic application in multiple myeloma.

Chen G, Gao X, Jia X, Wang Y, Xu L, Yu D, Chang S, Deng H, Hu K, Wang G, Li B, Xu Z, Lu Y, Wang H, Zhang T, Song D, Yang G, Wu X, Zhu H, Zhu W, Shi J. Chen G, et al. Among authors: lu y. Haematologica. 2024 Apr 1;109(4):1206-1219. doi: 10.3324/haematol.2023.282789. Haematologica. 2024. PMID: 37767568 Free PMC article.

7

Berberine derivative DCZ0358 induce oxidative damage by ROS-mediated JNK signaling in DLBCL cells.

Feng Q, Hu K, Hu H, Lu Y, Zhang H, Wang G, Zhang Q, Xu Z, Gao X, Jia X, Zhu H, Song D, Yi H, Peng Y, Wu X, Li B, Zhu W, Shi J. Feng Q, et al. Among authors: lu y. Int Immunopharmacol. 2023 Dec;125(Pt A):111139. doi: 10.1016/j.intimp.2023.111139. Epub 2023 Oct 30. Int Immunopharmacol. 2023. PMID: 37913572

8

TI17, a novel compound, exerts anti-MM activity by impairing Trip13 function of DSBs repair and enhancing DNA damage.

Chang S, Xiao W, Xie Y, Xu Z, Li B, Wang G, Hu K, Zhang Y, Zhou J, Song D, Zhu H, Wu X, Lu Y, Shi J, Zhu W. Chang S, et al. Among authors: lu y. Cancer Med. 2023 Dec;12(23):21321-21334. doi: 10.1002/cam4.6706. Epub 2023 Nov 9. Cancer Med. 2023. PMID: 37942576 Free PMC article.

9

A novel pterostilbene compound DCZ0825 induces macrophage M1 differentiation and Th1 polarization to exert anti-myeloma and immunomodulatory.

Zhang H, Hu K, Lu Y, Xu Z, Chen G, Yu D, Gao X, Feng Q, Jia X, Xu L, Zhou J, Wu X, Song D, Zhu H, Li B, Zhu W, Shi J. Zhang H, et al. Among authors: lu y. Int Immunopharmacol. 2024 Jan 25;127:111446. doi: 10.1016/j.intimp.2023.111446. Epub 2023 Dec 28. Int Immunopharmacol. 2024. PMID: 38157697

10

Induced skin aging by blue-light irradiation in human skin fibroblasts via TGF-β, JNK and EGFR pathways.

Ge G, Wang Y, Xu Y, Pu W, Tan Y, Liu P, Ding H, Lu YM, Wang J, Liu W, Ma Y. Ge G, et al. Among authors: lu ym. J Dermatol Sci. 2023 Aug;111(2):52-59. doi: 10.1016/j.jdermsci.2023.06.007. Epub 2023 Jun 28. J Dermatol Sci. 2023. PMID: 37438186 Free article.

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