Ohki R - Search Results

1

p53-PHLDA3-Akt Network: The Key Regulators of Neuroendocrine Tumorigenesis.

Chen Y, Ohki R. Chen Y, et al. Among authors: ohki r. Int J Mol Sci. 2020 Jun 8;21(11):4098. doi: 10.3390/ijms21114098. Int J Mol Sci. 2020. PMID: 32521808 Free PMC article. Review.

2

PH domain-only protein PHLDA3 is a p53-regulated repressor of Akt.

Kawase T, Ohki R, Shibata T, Tsutsumi S, Kamimura N, Inazawa J, Ohta T, Ichikawa H, Aburatani H, Tashiro F, Taya Y. Kawase T, et al. Among authors: ohki r. Cell. 2009 Feb 6;136(3):535-50. doi: 10.1016/j.cell.2008.12.002. Cell. 2009. PMID: 19203586 Free article.

3

PHLDA3 is a novel tumor suppressor of pancreatic neuroendocrine tumors.

Ohki R, Saito K, Chen Y, Kawase T, Hiraoka N, Saigawa R, Minegishi M, Aita Y, Yanai G, Shimizu H, Yachida S, Sakata N, Doi R, Kosuge T, Shimada K, Tycko B, Tsukada T, Kanai Y, Sumi S, Namiki H, Taya Y, Shibata T, Nakagama H. Ohki R, et al. Proc Natl Acad Sci U S A. 2014 Jun 10;111(23):E2404-13. doi: 10.1073/pnas.1319962111. Epub 2014 May 27. Proc Natl Acad Sci U S A. 2014. PMID: 24912192 Free PMC article.

4

IER5 generates a novel hypo-phosphorylated active form of HSF1 and contributes to tumorigenesis.

Asano Y, Kawase T, Okabe A, Tsutsumi S, Ichikawa H, Tatebe S, Kitabayashi I, Tashiro F, Namiki H, Kondo T, Semba K, Aburatani H, Taya Y, Nakagama H, Ohki R. Asano Y, et al. Among authors: ohki r. Sci Rep. 2016 Jan 12;6:19174. doi: 10.1038/srep19174. Sci Rep. 2016. PMID: 26754925 Free PMC article.

5

A vicious partnership between AKT and PHLDA3 to facilitate neuroendocrine tumors.

Takikawa M, Ohki R. Takikawa M, et al. Among authors: ohki r. Cancer Sci. 2017 Jun;108(6):1101-1108. doi: 10.1111/cas.13235. Epub 2017 May 22. Cancer Sci. 2017. PMID: 28295876 Free PMC article. Review.

6

Pleckstrin homology-like domain family A, member 3 (PHLDA3) deficiency improves islets engraftment through the suppression of hypoxic damage.

Sakata N, Yamaguchi Y, Chen Y, Shimoda M, Yoshimatsu G, Unno M, Sumi S, Ohki R. Sakata N, et al. Among authors: ohki r. PLoS One. 2017 Nov 9;12(11):e0187927. doi: 10.1371/journal.pone.0187927. eCollection 2017. PLoS One. 2017. PMID: 29121094 Free PMC article.

7

PHLDA1, another PHLDA family protein that inhibits Akt.

Chen Y, Takikawa M, Tsutsumi S, Yamaguchi Y, Okabe A, Shimada M, Kawase T, Sada A, Ezawa I, Takano Y, Nagata K, Suzuki Y, Semba K, Aburatani H, Ohki R. Chen Y, et al. Among authors: ohki r. Cancer Sci. 2018 Nov;109(11):3532-3542. doi: 10.1111/cas.13796. Epub 2018 Oct 13. Cancer Sci. 2018. PMID: 30207029 Free PMC article.

8

Recommendation of long-term and systemic management according to the risk factors in rectal NETs patients.

Kojima M, Chen Y, Ikeda K, Tsukada Y, Takahashi D, Kawano S, Amemiya K, Ito M, Ohki R, Ochiai A. Kojima M, et al. Among authors: ohki r. Sci Rep. 2019 Feb 20;9(1):2404. doi: 10.1038/s41598-018-37707-z. Sci Rep. 2019. PMID: 30787304 Free PMC article.

9

Nuclear import of IER5 is mediated by a classical bipartite nuclear localization signal and is required for HSF1 full activation.

Yamano S, Kimura M, Chen Y, Imamoto N, Ohki R. Yamano S, et al. Among authors: ohki r. Exp Cell Res. 2020 Jan 1;386(1):111686. doi: 10.1016/j.yexcr.2019.111686. Epub 2019 Nov 6. Exp Cell Res. 2020. PMID: 31669744

10

Identification and characterization of the binding sequences and target genes of p53 lacking the 1st transactivation domain.

Suzuki S, Tsutsumi S, Chen Y, Ozeki C, Okabe A, Kawase T, Aburatani H, Ohki R. Suzuki S, et al. Among authors: ohki r. Cancer Sci. 2020 Feb;111(2):451-466. doi: 10.1111/cas.14279. Epub 2020 Jan 13. Cancer Sci. 2020. PMID: 31834974 Free PMC article.

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