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Aminoacyl-tRNA synthetases as therapeutic targets.
Kwon NH, Fox PL, Kim S. Kwon NH, et al. Among authors: kim s. Nat Rev Drug Discov. 2019 Aug;18(8):629-650. doi: 10.1038/s41573-019-0026-3. Nat Rev Drug Discov. 2019. PMID: 31073243 Review.
Endogenous TLR2 ligand embedded in the catalytic region of human cysteinyl-tRNA synthetase 1.
Cho S, Kim SB, Lee Y, Song EC, Kim U, Kim HY, Suh JH, Goughnour PC, Kim Y, Yoon I, Shin NY, Kim D, Kim IK, Kang CY, Jang SY, Kim MH, Kim S. Cho S, et al. Among authors: kim sb, kim u, kim hy, kim ik, kim d, kim s, kim mh, kim y. J Immunother Cancer. 2020 May;8(1):e000277. doi: 10.1136/jitc-2019-000277. J Immunother Cancer. 2020. PMID: 32461342 Free PMC article.
AIMP2-DX2 provides therapeutic interface to control KRAS-driven tumorigenesis.
Kim DG, Choi Y, Lee Y, Lim S, Kong J, Song J, Roh Y, Harmalkar DS, Lee K, Goo JI, Cho HY, Mushtaq AU, Lee J, Park SH, Kim D, Min BS, Lee KY, Jeon YH, Lee S, Lee K, Kim S. Kim DG, et al. Among authors: kim d, kim s. Nat Commun. 2022 May 11;13(1):2572. doi: 10.1038/s41467-022-30149-2. Nat Commun. 2022. PMID: 35546148 Free PMC article.
Regulation of BRCA1 stability through the tandem UBX domains of isoleucyl-tRNA synthetase 1.
Chung S, Kang MS, Alimbetov DS, Mun GI, Yunn NO, Kim Y, Kim BG, Wie M, Lee EA, Ra JS, Oh JM, Lee D, Lee K, Kim J, Han SH, Kim KT, Chung WK, Nam KH, Park J, Lee B, Kim S, Zhao W, Ryu SH, Lee YS, Myung K, Cho Y. Chung S, et al. Among authors: kim bg, kim s, kim kt, kim j, kim y. Nat Commun. 2022 Nov 8;13(1):6732. doi: 10.1038/s41467-022-34612-y. Nat Commun. 2022. PMID: 36347866 Free PMC article.
Chemical induction of the interaction between AIMP2-DX2 and Siah1 to enhance ubiquitination.
Kim DG, Kim M, Goo JI, Kong J, Harmalkar DS, Lu Q, Sivaraman A, Nada H, Godesi S, Lee H, Song ME, Song E, Han KH, Kim W, Kim P, Choi WJ, Lee CH, Lee S, Choi Y, Kim S, Lee K. Kim DG, et al. Among authors: kim w, kim s, kim m, kim p. Cell Chem Biol. 2024 Nov 21;31(11):1958-1968.e8. doi: 10.1016/j.chembiol.2024.08.004. Epub 2024 Sep 10. Cell Chem Biol. 2024. PMID: 39260366
124,378 results
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