Yu J - Search Results

1

P2Y₁₄ Receptor Antagonists Reverse Chronic Neuropathic Pain in a Mouse Model.

Mufti F, Jung YH, Giancotti LA, Yu J, Chen Z, Phung NB, Jacobson KA, Salvemini D. Mufti F, et al. Among authors: yu j. ACS Med Chem Lett. 2020 Apr 30;11(6):1281-1286. doi: 10.1021/acsmedchemlett.0c00115. eCollection 2020 Jun 11. ACS Med Chem Lett. 2020. PMID: 32551012 Free PMC article.

2

N⁶-Substituted 5'-N-Methylcarbamoyl-4'-selenoadenosines as Potent and Selective A₃ Adenosine Receptor Agonists with Unusual Sugar Puckering and Nucleobase Orientation.

Yu J, Zhao LX, Park J, Lee HW, Sahu PK, Cui M, Moss SM, Hammes E, Warnick E, Gao ZG, Noh M, Choi S, Ahn HC, Choi J, Jacobson KA, Jeong LS. Yu J, et al. J Med Chem. 2017 Apr 27;60(8):3422-3437. doi: 10.1021/acs.jmedchem.7b00241. Epub 2017 Apr 19. J Med Chem. 2017. PMID: 28380296 Free PMC article.

3

Polypharmacology of N⁶-(3-Iodobenzyl)adenosine-5'-N-methyluronamide (IB-MECA) and Related A₃ Adenosine Receptor Ligands: Peroxisome Proliferator Activated Receptor (PPAR) γ Partial Agonist and PPARδ Antagonist Activity Suggests Their Antidiabetic Potential.

Yu J, Ahn S, Kim HJ, Lee M, Ahn S, Kim J, Jin SH, Lee E, Kim G, Cheong JH, Jacobson KA, Jeong LS, Noh M. Yu J, et al. J Med Chem. 2017 Sep 14;60(17):7459-7475. doi: 10.1021/acs.jmedchem.7b00805. Epub 2017 Aug 28. J Med Chem. 2017. PMID: 28799755 Free PMC article.

4

Bitopic fluorescent antagonists of the A_2A adenosine receptor based on pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine functionalized congeners.

Duroux R, Ciancetta A, Mannes P, Yu J, Boyapati S, Gizewski E, Yous S, Ciruela F, Auchampach JA, Gao ZG, Jacobson KA. Duroux R, et al. Among authors: yu j. Medchemcomm. 2017 Aug 1;8(8):1659-1667. doi: 10.1039/C7MD00247E. Epub 2017 Jun 22. Medchemcomm. 2017. PMID: 29250307 Free PMC article.

5

Structure-Guided Modification of Heterocyclic Antagonists of the P2Y₁₄ Receptor.

Yu J, Ciancetta A, Dudas S, Duca S, Lottermoser J, Jacobson KA. Yu J, et al. J Med Chem. 2018 Jun 14;61(11):4860-4882. doi: 10.1021/acs.jmedchem.8b00168. Epub 2018 May 16. J Med Chem. 2018. PMID: 29767967 Free PMC article.

6

Structure activity relationship of 2-arylalkynyl-adenine derivatives as human A₃ adenosine receptor antagonists.

Yu J, Mannes P, Jung YH, Ciancetta A, Bitant A, Lieberman DI, Khaznadar S, Auchampach JA, Gao ZG, Jacobson KA. Yu J, et al. Medchemcomm. 2018 Oct 18;9(11):1920-1932. doi: 10.1039/c8md00317c. eCollection 2018 Nov 1. Medchemcomm. 2018. PMID: 30568760 Free PMC article.

7

Exploration of Alternative Scaffolds for P2Y₁₄ Receptor Antagonists Containing a Biaryl Core.

Jung YH, Yu J, Wen Z, Salmaso V, Karcz TP, Phung NB, Chen Z, Duca S, Bennett JM, Dudas S, Salvemini D, Gao ZG, Cook DN, Jacobson KA. Jung YH, et al. Among authors: yu j. J Med Chem. 2020 Sep 10;63(17):9563-9589. doi: 10.1021/acs.jmedchem.0c00745. Epub 2020 Aug 6. J Med Chem. 2020. PMID: 32787142 Free PMC article.

8

Discovery and Structure-Activity Relationships of Novel Template, Truncated 1'-Homologated Adenosine Derivatives as Pure Dual PPARγ/δ Modulators.

An S, Kim G, Kim HJ, Ahn S, Kim HY, Ko H, Hyun YE, Nguyen M, Jeong J, Liu Z, Han J, Choi H, Yu J, Kim JW, Lee HW, Jacobson KA, Cho WJ, Kim YM, Kang KW, Noh M, Jeong LS. An S, et al. Among authors: yu j. J Med Chem. 2020 Dec 24;63(24):16012-16027. doi: 10.1021/acs.jmedchem.0c01874. Epub 2020 Dec 16. J Med Chem. 2020. PMID: 33325691 Free PMC article.

9

Interaction of A₃ adenosine receptor ligands with the human multidrug transporter ABCG2.

Abel B, Murakami M, Tosh DK, Yu J, Lusvarghi S, Campbell RG, Gao ZG, Jacobson KA, Ambudkar SV. Abel B, et al. Among authors: yu j. Eur J Med Chem. 2022 Mar 5;231:114103. doi: 10.1016/j.ejmech.2022.114103. Epub 2022 Jan 10. Eur J Med Chem. 2022. PMID: 35152062 Free PMC article.

10

GPCR Agonist-to-Antagonist Conversion: Enabling the Design of Nucleoside Functional Switches for the A_2A Adenosine Receptor.

Shiriaeva A, Park D, Kim G, Lee Y, Hou X, Jarhad DB, Kim G, Yu J, Hyun YE, Kim W, Gao ZG, Jacobson KA, Han GW, Stevens RC, Jeong LS, Choi S, Cherezov V. Shiriaeva A, et al. Among authors: yu j. J Med Chem. 2022 Sep 8;65(17):11648-11657. doi: 10.1021/acs.jmedchem.2c00462. Epub 2022 Aug 17. J Med Chem. 2022. PMID: 35977382 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

46,749 results

Search Page

Filters