Paul SM - Search Results

1

25-Hydroxycholesterol amplifies microglial IL-1β production in an apoE isoform-dependent manner.

Wong MY, Lewis M, Doherty JJ, Shi Y, Cashikar AG, Amelianchik A, Tymchuk S, Sullivan PM, Qian M, Covey DF, Petsko GA, Holtzman DM, Paul SM, Luo W. Wong MY, et al. Among authors: paul sm. J Neuroinflammation. 2020 Jun 17;17(1):192. doi: 10.1186/s12974-020-01869-3. J Neuroinflammation. 2020. PMID: 32552741 Free PMC article.

2

A Proinflammatory Stimulus Disrupts Hippocampal Plasticity and Learning via Microglial Activation and 25-Hydroxycholesterol.

Izumi Y, Cashikar AG, Krishnan K, Paul SM, Covey DF, Mennerick SJ, Zorumski CF. Izumi Y, et al. Among authors: paul sm. J Neurosci. 2021 Dec 8;41(49):10054-10064. doi: 10.1523/JNEUROSCI.1502-21.2021. Epub 2021 Nov 1. J Neurosci. 2021. PMID: 34725187 Free PMC article.

3

Human apolipoprotein E4 alters the amyloid-beta 40:42 ratio and promotes the formation of cerebral amyloid angiopathy in an amyloid precursor protein transgenic model.

Fryer JD, Simmons K, Parsadanian M, Bales KR, Paul SM, Sullivan PM, Holtzman DM. Fryer JD, et al. Among authors: paul sm. J Neurosci. 2005 Mar 16;25(11):2803-10. doi: 10.1523/JNEUROSCI.5170-04.2005. J Neurosci. 2005. PMID: 15772340 Free PMC article.

4

The low density lipoprotein receptor regulates the level of central nervous system human and murine apolipoprotein E but does not modify amyloid plaque pathology in PDAPP mice.

Fryer JD, Demattos RB, McCormick LM, O'Dell MA, Spinner ML, Bales KR, Paul SM, Sullivan PM, Parsadanian M, Bu G, Holtzman DM. Fryer JD, et al. Among authors: paul sm. J Biol Chem. 2005 Jul 8;280(27):25754-9. doi: 10.1074/jbc.M502143200. Epub 2005 May 11. J Biol Chem. 2005. PMID: 15888448 Free article.

5

Intracerebral adeno-associated virus gene delivery of apolipoprotein E2 markedly reduces brain amyloid pathology in Alzheimer's disease mouse models.

Zhao L, Gottesdiener AJ, Parmar M, Li M, Kaminsky SM, Chiuchiolo MJ, Sondhi D, Sullivan PM, Holtzman DM, Crystal RG, Paul SM. Zhao L, et al. Among authors: paul sm. Neurobiol Aging. 2016 Aug;44:159-172. doi: 10.1016/j.neurobiolaging.2016.04.020. Epub 2016 Apr 30. Neurobiol Aging. 2016. PMID: 27318144

6

ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy.

Shi Y, Yamada K, Liddelow SA, Smith ST, Zhao L, Luo W, Tsai RM, Spina S, Grinberg LT, Rojas JC, Gallardo G, Wang K, Roh J, Robinson G, Finn MB, Jiang H, Sullivan PM, Baufeld C, Wood MW, Sutphen C, McCue L, Xiong C, Del-Aguila JL, Morris JC, Cruchaga C; Alzheimer’s Disease Neuroimaging Initiative; Fagan AM, Miller BL, Boxer AL, Seeley WW, Butovsky O, Barres BA, Paul SM, Holtzman DM. Shi Y, et al. Among authors: paul sm. Nature. 2017 Sep 28;549(7673):523-527. doi: 10.1038/nature24016. Epub 2017 Sep 20. Nature. 2017. PMID: 28959956 Free PMC article.

7

[No title available]

[No authors listed] [No authors listed] PMID: 35109157

8

Microglial internalization and degradation of pathological tau is enhanced by an anti-tau monoclonal antibody.

Luo W, Liu W, Hu X, Hanna M, Caravaca A, Paul SM. Luo W, et al. Among authors: paul sm. Sci Rep. 2015 Jun 9;5:11161. doi: 10.1038/srep11161. Sci Rep. 2015. PMID: 26057852 Free PMC article.

9

Brain to plasma amyloid-beta efflux: a measure of brain amyloid burden in a mouse model of Alzheimer's disease.

DeMattos RB, Bales KR, Cummins DJ, Paul SM, Holtzman DM. DeMattos RB, et al. Among authors: paul sm. Science. 2002 Mar 22;295(5563):2264-7. doi: 10.1126/science.1067568. Science. 2002. PMID: 11910111

10

Human and murine ApoE markedly alters A beta metabolism before and after plaque formation in a mouse model of Alzheimer's disease.

Fagan AM, Watson M, Parsadanian M, Bales KR, Paul SM, Holtzman DM. Fagan AM, et al. Among authors: paul sm. Neurobiol Dis. 2002 Apr;9(3):305-18. doi: 10.1006/nbdi.2002.0483. Neurobiol Dis. 2002. PMID: 11950276

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