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Mitochondrial protein interaction landscape of SS-31.
Chavez JD, Tang X, Campbell MD, Reyes G, Kramer PA, Stuppard R, Keller A, Zhang H, Rabinovitch PS, Marcinek DJ, Bruce JE. Chavez JD, et al. Among authors: zhang h. Proc Natl Acad Sci U S A. 2020 Jun 30;117(26):15363-15373. doi: 10.1073/pnas.2002250117. Epub 2020 Jun 17. Proc Natl Acad Sci U S A. 2020. PMID: 32554501 Free PMC article.
Heart specific knockout of Ndufs4 ameliorates ischemia reperfusion injury.
Zhang H, Gong G, Wang P, Zhang Z, Kolwicz SC, Rabinovitch PS, Tian R, Wang W. Zhang H, et al. Among authors: zhang z. J Mol Cell Cardiol. 2018 Oct;123:38-45. doi: 10.1016/j.yjmcc.2018.08.022. Epub 2018 Aug 27. J Mol Cell Cardiol. 2018. PMID: 30165037 Free PMC article.
Late-life restoration of mitochondrial function reverses cardiac dysfunction in old mice.
Chiao YA, Zhang H, Sweetwyne M, Whitson J, Ting YS, Basisty N, Pino LK, Quarles E, Nguyen NH, Campbell MD, Zhang T, Gaffrey MJ, Merrihew G, Wang L, Yue Y, Duan D, Granzier HL, Szeto HH, Qian WJ, Marcinek D, MacCoss MJ, Rabinovitch P. Chiao YA, et al. Among authors: zhang t, zhang h. Elife. 2020 Jul 10;9:e55513. doi: 10.7554/eLife.55513. Elife. 2020. PMID: 32648542 Free PMC article.
SS-31 and NMN: Two paths to improve metabolism and function in aged hearts.
Whitson JA, Bitto A, Zhang H, Sweetwyne MT, Coig R, Bhayana S, Shankland EG, Wang L, Bammler TK, Mills KF, Imai SI, Conley KE, Marcinek DJ, Rabinovitch PS. Whitson JA, et al. Among authors: zhang h. Aging Cell. 2020 Oct;19(10):e13213. doi: 10.1111/acel.13213. Epub 2020 Aug 11. Aging Cell. 2020. PMID: 32779818 Free PMC article.
An Analysis of Metabolic Changes in the Retina and Retinal Pigment Epithelium of Aging Mice.
Tsantilas KA, Cleghorn WM, Bisbach CM, Whitson JA, Hass DT, Robbings BM, Sadilek M, Linton JD, Rountree AM, Valencia AP, Sweetwyne MT, Campbell MD, Zhang H, Jankowski CSR, Sweet IR, Marcinek DJ, Rabinovitch PS, Hurley JB. Tsantilas KA, et al. Among authors: zhang h. Invest Ophthalmol Vis Sci. 2021 Nov 1;62(14):20. doi: 10.1167/iovs.62.14.20. Invest Ophthalmol Vis Sci. 2021. PMID: 34797906 Free PMC article.
Age-related disruption of the proteome and acetylome in mouse hearts is associated with loss of function and attenuated by elamipretide (SS-31) and nicotinamide mononucleotide (NMN) treatment.
Whitson JA, Johnson R, Wang L, Bammler TK, Imai SI, Zhang H, Fredrickson J, Latorre-Esteves E, Bitto A, MacCoss MJ, Rabinovitch PS. Whitson JA, et al. Among authors: zhang h. Geroscience. 2022 Jun;44(3):1621-1639. doi: 10.1007/s11357-022-00564-w. Epub 2022 Apr 13. Geroscience. 2022. PMID: 35416576 Free PMC article.
Mitochondrial proton leak in cardiac aging.
Qi X, Rusch NJ, Fan J, Mora CJ, Xie L, Mu S, Rabinovitch PS, Zhang H. Qi X, et al. Among authors: zhang h. Geroscience. 2023 Aug;45(4):2135-2143. doi: 10.1007/s11357-023-00757-x. Epub 2023 Mar 1. Geroscience. 2023. PMID: 36856945 Free PMC article. Review.
Melatonin prevents abnormal mitochondrial dynamics resulting from the neurotoxicity of cadmium by blocking calcium-dependent translocation of Drp1 to the mitochondria.
Xu S, Pi H, Zhang L, Zhang N, Li Y, Zhang H, Tang J, Li H, Feng M, Deng P, Guo P, Tian L, Xie J, He M, Lu Y, Zhong M, Zhang Y, Wang W, Reiter RJ, Yu Z, Zhou Z. Xu S, et al. Among authors: zhang n, zhang l, zhang h, zhang y. J Pineal Res. 2016 Apr;60(3):291-302. doi: 10.1111/jpi.12310. Epub 2016 Feb 15. J Pineal Res. 2016. PMID: 26732476
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