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Drug compound screening in single and integrated multi-organoid body-on-a-chip systems.
Skardal A, Aleman J, Forsythe S, Rajan S, Murphy S, Devarasetty M, Pourhabibi Zarandi N, Nzou G, Wicks R, Sadri-Ardekani H, Bishop C, Soker S, Hall A, Shupe T, Atala A. Skardal A, et al. Among authors: nzou g. Biofabrication. 2020 Feb 26;12(2):025017. doi: 10.1088/1758-5090/ab6d36. Biofabrication. 2020. PMID: 32101533
Microtubule-Stabilizing 1,2,4-Triazolo[1,5-a]pyrimidines as Candidate Therapeutics for Neurodegenerative Disease: Matched Molecular Pair Analyses and Computational Studies Reveal New Structure-Activity Insights.
Alle T, Varricchio C, Yao Y, Lucero B, Nzou G, Demuro S, Muench M, Vuong KD, Oukoloff K, Cornec AS, Francisco KR, Caffrey CR, Lee VM, Smith AB 3rd, Brancale A, Brunden KR, Ballatore C. Alle T, et al. Among authors: nzou g. J Med Chem. 2023 Jan 12;66(1):435-459. doi: 10.1021/acs.jmedchem.2c01411. Epub 2022 Dec 19. J Med Chem. 2023. PMID: 36534051 Free PMC article.
Evaluation of the Structure-Activity Relationship of Microtubule-Targeting 1,2,4-Triazolo[1,5-a]pyrimidines Identifies New Candidates for Neurodegenerative Tauopathies.
Oukoloff K, Nzou G, Varricchio C, Lucero B, Alle T, Kovalevich J, Monti L, Cornec AS, Yao Y, James MJ, Trojanowski JQ, Lee VM, Smith AB 3rd, Brancale A, Brunden KR, Ballatore C. Oukoloff K, et al. Among authors: nzou g. J Med Chem. 2021 Jan 28;64(2):1073-1102. doi: 10.1021/acs.jmedchem.0c01605. Epub 2021 Jan 7. J Med Chem. 2021. PMID: 33411523 Free PMC article.