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Page 1
Molecular basis of β-arrestin coupling to formoterol-bound β1-adrenoceptor.
Lee Y, Warne T, Nehmé R, Pandey S, Dwivedi-Agnihotri H, Chaturvedi M, Edwards PC, García-Nafría J, Leslie AGW, Shukla AK, Tate CG. Lee Y, et al. Among authors: shukla ak. Nature. 2020 Jul;583(7818):862-866. doi: 10.1038/s41586-020-2419-1. Epub 2020 Jun 17. Nature. 2020. PMID: 32555462 Free PMC article.
Structure of active β-arrestin-1 bound to a G-protein-coupled receptor phosphopeptide.
Shukla AK, Manglik A, Kruse AC, Xiao K, Reis RI, Tseng WC, Staus DP, Hilger D, Uysal S, Huang LY, Paduch M, Tripathi-Shukla P, Koide A, Koide S, Weis WI, Kossiakoff AA, Kobilka BK, Lefkowitz RJ. Shukla AK, et al. Nature. 2013 May 2;497(7447):137-41. doi: 10.1038/nature12120. Epub 2013 Apr 21. Nature. 2013. PMID: 23604254 Free PMC article.
Visualization of arrestin recruitment by a G-protein-coupled receptor.
Shukla AK, Westfield GH, Xiao K, Reis RI, Huang LY, Tripathi-Shukla P, Qian J, Li S, Blanc A, Oleskie AN, Dosey AM, Su M, Liang CR, Gu LL, Shan JM, Chen X, Hanna R, Choi M, Yao XJ, Klink BU, Kahsai AW, Sidhu SS, Koide S, Penczek PA, Kossiakoff AA, Woods VL Jr, Kobilka BK, Skiniotis G, Lefkowitz RJ. Shukla AK, et al. Nature. 2014 Aug 14;512(7513):218-222. doi: 10.1038/nature13430. Epub 2014 Jun 22. Nature. 2014. PMID: 25043026 Free PMC article.
Functional competence of a partially engaged GPCR-β-arrestin complex.
Kumari P, Srivastava A, Banerjee R, Ghosh E, Gupta P, Ranjan R, Chen X, Gupta B, Gupta C, Jaiman D, Shukla AK. Kumari P, et al. Among authors: shukla ak. Nat Commun. 2016 Nov 9;7:13416. doi: 10.1038/ncomms13416. Nat Commun. 2016. PMID: 27827372 Free PMC article.
Biased Opioid Receptor Ligands: Gain without Pain.
Ranjan R, Pandey S, Shukla AK. Ranjan R, et al. Among authors: shukla ak. Trends Endocrinol Metab. 2017 Apr;28(4):247-249. doi: 10.1016/j.tem.2017.01.001. Epub 2017 Jan 16. Trends Endocrinol Metab. 2017. PMID: 28110810 Review.
A synthetic intrabody-based selective and generic inhibitor of GPCR endocytosis.
Ghosh E, Srivastava A, Baidya M, Kumari P, Dwivedi H, Nidhi K, Ranjan R, Dogra S, Koide A, Yadav PN, Sidhu SS, Koide S, Shukla AK. Ghosh E, et al. Among authors: shukla ak. Nat Nanotechnol. 2017 Dec;12(12):1190-1198. doi: 10.1038/nnano.2017.188. Epub 2017 Oct 2. Nat Nanotechnol. 2017. PMID: 28967893 Free PMC article.
GPCR Signaling: The Interplay of Gαi and β-arrestin.
Dwivedi H, Baidya M, Shukla AK. Dwivedi H, et al. Among authors: shukla ak. Curr Biol. 2018 Apr 2;28(7):R324-R327. doi: 10.1016/j.cub.2018.02.027. Curr Biol. 2018. PMID: 29614294 Free article.
558 results