Legoabe LJ - Search Results

1

6-Nitro-1-benzylquinolones exhibiting specific antitubercular activity.

Beteck RM, Jordaan A, Swart T, Van Der Kooy F, Warner DF, Hoppe HC, Legoabe LJ. Beteck RM, et al. Among authors: legoabe lj. Chem Biol Drug Des. 2020 Dec;96(6):1387-1394. doi: 10.1111/cbdd.13747. Epub 2020 Jul 26. Chem Biol Drug Des. 2020. PMID: 32558257

2

The Synthesis and Evaluation of C7-Substituted α-Tetralone Derivatives as Inhibitors of Monoamine Oxidase.

Legoabe LJ, Petzer A, Petzer JP. Legoabe LJ, et al. Chem Biol Drug Des. 2015 Oct;86(4):895-904. doi: 10.1111/cbdd.12508. Epub 2015 Jan 31. Chem Biol Drug Des. 2015. PMID: 25581511

3

Evaluation of 2-benzylidene-1-tetralone derivatives as antagonists of A₁ and A_2A adenosine receptors.

Legoabe LJ, Van der Walt MM, Terre'Blanche G. Legoabe LJ, et al. Chem Biol Drug Des. 2018 Jan;91(1):234-244. doi: 10.1111/cbdd.13074. Epub 2017 Aug 16. Chem Biol Drug Des. 2018. PMID: 28734058

4

Quinolone-isoniazid hybrids: synthesis and preliminary in vitro cytotoxicity and anti-tuberculosis evaluation.

Beteck RM, Seldon R, Jordaan A, Warner DF, Hoppe HC, Laming D, Legoabe LJ, Khanye SD. Beteck RM, et al. Among authors: legoabe lj. Medchemcomm. 2019 Jan 11;10(2):326-331. doi: 10.1039/c8md00480c. eCollection 2019 Feb 1. Medchemcomm. 2019. PMID: 30881619 Free PMC article.

5

Anti-Trypanosomal and Antimalarial Properties of Tetralone Derivatives and Structurally Related Benzocycloalkanones.

Beteck RM, Legoabe LJ, Isaacs M, Khanye SD, Laming D, Hoppe HC. Beteck RM, et al. Among authors: legoabe lj. Medicina (Kaunas). 2019 May 24;55(5):206. doi: 10.3390/medicina55050206. Medicina (Kaunas). 2019. PMID: 31137665 Free PMC article.

6

Synthesis and evaluation of 7-azaindole derivatives bearing benzocycloalkanone motifs as protein kinase inhibitors.

Qhobosheane MA, Legoabe LJ, Josselin B, Bach S, Ruchaud S, Petzer JP, Beteck RM. Qhobosheane MA, et al. Among authors: legoabe lj. Bioorg Med Chem. 2020 Jun 1;28(11):115468. doi: 10.1016/j.bmc.2020.115468. Epub 2020 Mar 31. Bioorg Med Chem. 2020. PMID: 32284225

7

Synthesis and evaluation of C3 substituted chalcone-based derivatives of 7-azaindole as protein kinase inhibitors.

Qhobosheane MA, Legoabe LJ, Josselin B, Bach S, Ruchaud S, Beteck RM. Qhobosheane MA, et al. Among authors: legoabe lj. Chem Biol Drug Des. 2020 Dec;96(6):1395-1407. doi: 10.1111/cbdd.13748. Epub 2020 Aug 18. Chem Biol Drug Des. 2020. PMID: 32558155

8

An Update on Development of Small-Molecule Plasmodial Kinase Inhibitors.

Moolman C, Sluis RV, Beteck RM, Legoabe LJ. Moolman C, et al. Among authors: legoabe lj. Molecules. 2020 Nov 7;25(21):5182. doi: 10.3390/molecules25215182. Molecules. 2020. PMID: 33171706 Free PMC article. Review.

9

Metronidazole-conjugates: A comprehensive review of recent developments towards synthesis and medicinal perspective.

Patel OPS, Jesumoroti OJ, Legoabe LJ, Beteck RM. Patel OPS, et al. Among authors: legoabe lj. Eur J Med Chem. 2021 Jan 15;210:112994. doi: 10.1016/j.ejmech.2020.112994. Epub 2020 Nov 4. Eur J Med Chem. 2021. PMID: 33234343 Review.

10

Antimalarial application of quinones: A recent update.

Patel OPS, Beteck RM, Legoabe LJ. Patel OPS, et al. Among authors: legoabe lj. Eur J Med Chem. 2021 Jan 15;210:113084. doi: 10.1016/j.ejmech.2020.113084. Epub 2020 Dec 5. Eur J Med Chem. 2021. PMID: 33333397 Review.

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