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Application of a Rat Liver Drug Bioactivation Transcriptional Response Assay Early in Drug Development That Informs Chemically Reactive Metabolite Formation and Potential for Drug-induced Liver Injury.
Monroe JJ, Tanis KQ, Podtelezhnikov AA, Nguyen T, Machotka SV, Lynch D, Evers R, Palamanda J, Miller RR, Pippert T, Cabalu TD, Johnson TE, Aslamkhan AG, Kang W, Tamburino AM, Mitra K, Agrawal NGB, Sistare FD. Monroe JJ, et al. Among authors: agrawal ngb. Toxicol Sci. 2020 Sep 1;177(1):281-299. doi: 10.1093/toxsci/kfaa088. Toxicol Sci. 2020. PMID: 32559301 Free PMC article.
Pharmacokinetics of etoricoxib in patients with renal impairment.
Agrawal NG, Matthews CZ, Mazenko RS, Kline WF, Woolf EJ, Porras AG, Geer LA, Wong PH, Cho M, Cote J, Marbury TC, Moncrief JW, Alcorn H Jr, Swan S, Sack MR, Robson RA, Petty KJ, Schwartz JI, Gottesdiener KM. Agrawal NG, et al. J Clin Pharmacol. 2004 Jan;44(1):48-58. doi: 10.1177/0091270003260338. J Clin Pharmacol. 2004. PMID: 14681341
Lack of meaningful effect of ridaforolimus on the pharmacokinetics of midazolam in cancer patients: model prediction and clinical confirmation.
Stroh M, Talaty J, Sandhu P, McCrea J, Patnaik A, Tolcher A, Palcza J, Orford K, Breidinger S, Narasimhan N, Panebianco D, Lush R, Papadopoulos KP, Wagner JA, Trucksis M, Agrawal N. Stroh M, et al. J Clin Pharmacol. 2014 Nov;54(11):1256-62. doi: 10.1002/jcph.331. Epub 2014 May 24. J Clin Pharmacol. 2014. PMID: 24827931 Clinical Trial.
Pharmacokinetics of etoricoxib in patients with hepatic impairment.
Agrawal NG, Rose MJ, Matthews CZ, Woolf EJ, Porras AG, Geer LA, Larson PJ, Cote J, Dilzer SC, Lasseter KC, Alam I, Petty KJ, Gottesdiener KM. Agrawal NG, et al. J Clin Pharmacol. 2003 Oct;43(10):1136-48. doi: 10.1177/0091270003257219. J Clin Pharmacol. 2003. PMID: 14517196 Clinical Trial.
28 results