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SARS-CoV-2-specific T cells exhibit unique features reflecting robust helper function, lack of terminal differentiation, and high proliferative potential.
Neidleman J, Luo X, Frouard J, Xie G, Gill G, Stein ES, McGregor M, Ma T, George A, Kosters A, Greene WC, Vasquez J, Ghosn E, Lee S, Roan NR. Neidleman J, et al. Among authors: lee s. bioRxiv [Preprint]. 2020 Aug 3:2020.06.08.138826. doi: 10.1101/2020.06.08.138826. bioRxiv. 2020. Update in: Cell Rep Med. 2020 Sep 22;1(6):100081. doi: 10.1016/j.xcrm.2020.100081 PMID: 32577663 Free PMC article. Updated. Preprint.
Tissue memory CD4+ T cells expressing IL-7 receptor-alpha (CD127) preferentially support latent HIV-1 infection.
Hsiao F, Frouard J, Gramatica A, Xie G, Telwatte S, Lee GQ, Roychoudhury P, Schwarzer R, Luo X, Yukl SA, Lee S, Hoh R, Deeks SG, Jones RB, Cavrois M, Greene WC, Roan NR. Hsiao F, et al. Among authors: lee gq, lee s. PLoS Pathog. 2020 Apr 30;16(4):e1008450. doi: 10.1371/journal.ppat.1008450. eCollection 2020 Apr. PLoS Pathog. 2020. PMID: 32353080 Free PMC article.
SARS-CoV-2-Specific T Cells Exhibit Phenotypic Features of Helper Function, Lack of Terminal Differentiation, and High Proliferation Potential.
Neidleman J, Luo X, Frouard J, Xie G, Gill G, Stein ES, McGregor M, Ma T, George AF, Kosters A, Greene WC, Vasquez J, Ghosn E, Lee S, Roan NR. Neidleman J, et al. Among authors: lee s. Cell Rep Med. 2020 Sep 22;1(6):100081. doi: 10.1016/j.xcrm.2020.100081. Epub 2020 Aug 19. Cell Rep Med. 2020. PMID: 32839763 Free PMC article.
Distinctive features of SARS-CoV-2-specific T cells predict recovery from severe COVID-19.
Neidleman J, Luo X, George AF, McGregor M, Yang J, Yun C, Murray V, Gill G, Greene WC, Vasquez J, Lee S, Ghosn E, Lynch K, Roan NR. Neidleman J, et al. Among authors: lee s. medRxiv [Preprint]. 2021 Feb 5:2021.01.22.21250054. doi: 10.1101/2021.01.22.21250054. medRxiv. 2021. Update in: Cell Rep. 2021 Jul 20;36(3):109414. doi: 10.1016/j.celrep.2021.109414 PMID: 33532792 Free PMC article. Updated. Preprint.
Protracted yet coordinated differentiation of long-lived SARS-CoV-2-specific CD8+ T cells during COVID-19 convalescence.
Ma T, Ryu H, McGregor M, Babcock B, Neidleman J, Xie G, George AF, Frouard J, Murray V, Gill G, Ghosn E, Newell E, Lee S, Roan NR. Ma T, et al. Among authors: lee s. bioRxiv [Preprint]. 2021 Apr 29:2021.04.28.441880. doi: 10.1101/2021.04.28.441880. bioRxiv. 2021. Update in: J Immunol. 2021 Sep 1;207(5):1344-1356. doi: 10.4049/jimmunol.2100465 PMID: 33948597 Free PMC article. Updated. Preprint.
mRNA vaccine-induced T cells respond identically to SARS-CoV-2 variants of concern but differ in longevity and homing properties depending on prior infection status.
Neidleman J, Luo X, McGregor M, Xie G, Murray V, Greene WC, Lee SA, Roan NR. Neidleman J, et al. bioRxiv [Preprint]. 2021 Jul 29:2021.05.12.443888. doi: 10.1101/2021.05.12.443888. bioRxiv. 2021. Update in: Elife. 2021 Oct 12;10:e72619. doi: 10.7554/eLife.72619 PMID: 34013277 Free PMC article. Updated. Preprint.
A common allele of HLA mediates asymptomatic SARS-CoV-2 infection.
Augusto DG, Yusufali T, Sabatino JJ Jr, Peyser ND, Murdolo LD, Butcher X, Murray V, Pae V, Sarvadhavabhatla S, Beltran F, Gill G, Lynch K, Yun C, Maguire C, Peluso MJ, Hoh R, Henrich TJ, Deeks SG, Davidson M, Lu S, Goldberg SA, Kelly JD, Martin JN, Viera-Green CA, Spellman SR, Langton DJ, Lee S, Marcus GM, Olgin JE, Pletcher MJ, Gras S, Maiers M, Hollenbach JA. Augusto DG, et al. Among authors: lee s. medRxiv [Preprint]. 2022 Oct 12:2021.05.13.21257065. doi: 10.1101/2021.05.13.21257065. medRxiv. 2022. Update in: Nature. 2023 Aug;620(7972):128-136. doi: 10.1038/s41586-023-06331-x PMID: 34031661 Free PMC article. Updated. Preprint.
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