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Page 1
Biomarkers and Precision Medicine: State of the Art.
Sarma A, Calfee CS, Ware LB. Sarma A, et al. Among authors: calfee cs. Crit Care Clin. 2020 Jan;36(1):155-165. doi: 10.1016/j.ccc.2019.08.012. Epub 2019 Oct 22. Crit Care Clin. 2020. PMID: 31733677 Review.
Is a "Cytokine Storm" Relevant to COVID-19?
Sinha P, Matthay MA, Calfee CS. Sinha P, et al. Among authors: calfee cs. JAMA Intern Med. 2020 Sep 1;180(9):1152-1154. doi: 10.1001/jamainternmed.2020.3313. JAMA Intern Med. 2020. PMID: 32602883 No abstract available.
Effect of Hydrocortisone on Mortality and Organ Support in Patients With Severe COVID-19: The REMAP-CAP COVID-19 Corticosteroid Domain Randomized Clinical Trial.
Angus DC, Derde L, Al-Beidh F, Annane D, Arabi Y, Beane A, van Bentum-Puijk W, Berry L, Bhimani Z, Bonten M, Bradbury C, Brunkhorst F, Buxton M, Buzgau A, Cheng AC, de Jong M, Detry M, Estcourt L, Fitzgerald M, Goossens H, Green C, Haniffa R, Higgins AM, Horvat C, Hullegie SJ, Kruger P, Lamontagne F, Lawler PR, Linstrum K, Litton E, Lorenzi E, Marshall J, McAuley D, McGlothin A, McGuinness S, McVerry B, Montgomery S, Mouncey P, Murthy S, Nichol A, Parke R, Parker J, Rowan K, Sanil A, Santos M, Saunders C, Seymour C, Turner A, van de Veerdonk F, Venkatesh B, Zarychanski R, Berry S, Lewis RJ, McArthur C, Webb SA, Gordon AC; Writing Committee for the REMAP-CAP Investigators; Al-Beidh F, Angus D, Annane D, Arabi Y, van Bentum-Puijk W, Berry S, Beane A, Bhimani Z, Bonten M, Bradbury C, Brunkhorst F, Buxton M, Cheng A, De Jong M, Derde L, Estcourt L, Goossens H, Gordon A, Green C, Haniffa R, Lamontagne F, Lawler P, Litton E, Marshall J, McArthur C, McAuley D, McGuinness S, McVerry B, Montgomery S, Mouncey P, Murthy S, Nichol A, Parke R, Rowan K, Seymour C, Turner A, van de Veerdonk F, Webb S, Zarychanski R, Campbell L, Forbes A, Gattas D, Heritier S, Higgins L, Kruger P, Peake S, Presne… See abstract for full author list ➔ Angus DC, et al. JAMA. 2020 Oct 6;324(13):1317-1329. doi: 10.1001/jama.2020.17022. JAMA. 2020. PMID: 32876697 Free PMC article. Clinical Trial.
Effect of Hydroxychloroquine on Clinical Status at 14 Days in Hospitalized Patients With COVID-19: A Randomized Clinical Trial.
Self WH, Semler MW, Leither LM, Casey JD, Angus DC, Brower RG, Chang SY, Collins SP, Eppensteiner JC, Filbin MR, Files DC, Gibbs KW, Ginde AA, Gong MN, Harrell FE Jr, Hayden DL, Hough CL, Johnson NJ, Khan A, Lindsell CJ, Matthay MA, Moss M, Park PK, Rice TW, Robinson BRH, Schoenfeld DA, Shapiro NI, Steingrub JS, Ulysse CA, Weissman A, Yealy DM, Thompson BT, Brown SM; National Heart, Lung, and Blood Institute PETAL Clinical Trials Network; Steingrub J, Smithline H, Tiru B, Tidswell M, Kozikowski L, Thornton-Thompson S, De Souza L, Hou P, Baron R, Massaro A, Aisiku I, Fredenburgh L, Seethala R, Johnsky L, Riker R, Seder D, May T, Baumann M, Eldridge A, Lord C, Shapiro N, Talmor D, O’Mara T, Kirk C, Harrison K, Kurt L, Schermerhorn M, Banner-Goodspeed V, Boyle K, Dubosh N, Filbin M, Hibbert K, Parry B, Lavin-Parsons K, Pulido N, Lilley B, Lodenstein C, Margolin J, Brait K, Jones A, Galbraith J, Peacock R, Nandi U, Wachs T, Matthay M, Liu K, Kangelaris K, Wang R, Calfee C, Yee K, Hendey G, Chang S, Lim G, Qadir N, Tam A, Beutler R, Levitt J, Wilson J, Rogers A, Vojnik R, Roque J, Albertson T, Chenoweth J, Adams J, Pearson S, Juarez M, Almasri E, Fayed M, Hughes A, Hillard S, Huebinger… See abstract for full author list ➔ Self WH, et al. JAMA. 2020 Dec 1;324(21):2165-2176. doi: 10.1001/jama.2020.22240. JAMA. 2020. PMID: 33165621 Free PMC article. Clinical Trial.
Assessing the importance of interleukin-6 in COVID-19 - Authors' reply.
Leisman DE, Ronner L, Pinotti R, Taylor MD, Sinha P, Calfee CS, Hirayama AV, Mastroianni F, Turtle CJ, Harhay MO, Legrand M, Deutschman CS. Leisman DE, et al. Among authors: calfee cs. Lancet Respir Med. 2021 Feb;9(2):e14-e15. doi: 10.1016/S2213-2600(20)30603-2. Epub 2021 Jan 15. Lancet Respir Med. 2021. PMID: 33460572 Free PMC article. No abstract available.
COVID-19 ARDS is characterized by a dysregulated host response that differs from cytokine storm and is modified by dexamethasone.
Sarma A, Christenson SA, Mick E, DeVoe C, Deiss T, Pisco AO, Ghale R, Jauregui A, Byrne A, Moazed F, Spottiswoode N, Sinha P, Zha BS, Neff N, Tan M, Serpa PH, Ansel KM, Wilson JG, Leligdowicz A, Siegel ER, Sirota M, DeRisi JL, Matthay MA; COMET Consortium; Hendrickson CM, Kangelaris KN, Krummel MF, Woodruff PG, Erle DJ, Calfee CS, Langelier CR. Sarma A, et al. Among authors: calfee cs. Res Sq [Preprint]. 2021 Jan 14:rs.3.rs-141578. doi: 10.21203/rs.3.rs-141578/v1. Res Sq. 2021. Update in: Nat Commun. 2021 Aug 26;12(1):5152. doi: 10.1038/s41467-021-25040-5 PMID: 33469573 Free PMC article. Updated. Preprint.
Impaired immune signaling and changes in the lung microbiome precede secondary bacterial pneumonia in COVID-19.
Tsitsiklis A, Zha BS, Byrne A, DeVoe C, Rackaityte E, Levan S, Sunshine S, Mick E, Ghale R, Love C, Tarashansky AJ, Pisco A, Albright J, Jauregui A, Sarma A, Neff N, Serpa PH, Deiss TJ, Kistler A, Carrillo S, Ansel KM, Leligdowicz A, Christenson S, Detweiler A, Jones NG, Wu B, Darmanis S, Lynch SV, DeRisi JL; COMET Consortium; Matthay MA, Hendrickson CM, Kangelaris KN, Krummel MF, Woodruff PG, Erle DJ, Rosenberg O, Calfee CS, Langelier CR. Tsitsiklis A, et al. Among authors: calfee cs. medRxiv [Preprint]. 2021 Nov 30:2021.03.23.21253487. doi: 10.1101/2021.03.23.21253487. medRxiv. 2021. PMID: 33791731 Free PMC article. Preprint.
338 results