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Obesity/Type 2 Diabetes-Associated Liver Tumors Are Sensitive to Cyclin D1 Deficiency.
Luo C, Liang J, Sharabi K, Hatting M, Perry EA, Tavares CDJ, Goyal L, Srivastava A, Bilodeau M, Zhu AX, Sicinski P, Puigserver P. Luo C, et al. Among authors: puigserver p. Cancer Res. 2020 Aug 15;80(16):3215-3221. doi: 10.1158/0008-5472.CAN-20-0106. Epub 2020 Jun 30. Cancer Res. 2020. PMID: 32606000 Free PMC article.
Cyclin D1-Cdk4 controls glucose metabolism independently of cell cycle progression.
Lee Y, Dominy JE, Choi YJ, Jurczak M, Tolliday N, Camporez JP, Chim H, Lim JH, Ruan HB, Yang X, Vazquez F, Sicinski P, Shulman GI, Puigserver P. Lee Y, et al. Among authors: puigserver p. Nature. 2014 Jun 26;510(7506):547-51. doi: 10.1038/nature13267. Epub 2014 May 25. Nature. 2014. PMID: 24870244 Free PMC article.
Molecular pathophysiology of hepatic glucose production.
Sharabi K, Tavares CD, Rines AK, Puigserver P. Sharabi K, et al. Among authors: puigserver p. Mol Aspects Med. 2015 Dec;46:21-33. doi: 10.1016/j.mam.2015.09.003. Epub 2015 Nov 5. Mol Aspects Med. 2015. PMID: 26549348 Free PMC article. Review.
The Methionine Transamination Pathway Controls Hepatic Glucose Metabolism through Regulation of the GCN5 Acetyltransferase and the PGC-1α Transcriptional Coactivator.
Tavares CD, Sharabi K, Dominy JE, Lee Y, Isasa M, Orozco JM, Jedrychowski MP, Kamenecka TM, Griffin PR, Gygi SP, Puigserver P. Tavares CD, et al. Among authors: puigserver p. J Biol Chem. 2016 May 13;291(20):10635-45. doi: 10.1074/jbc.M115.706200. Epub 2016 Mar 28. J Biol Chem. 2016. PMID: 27022023 Free PMC article.
Breaking BRAF(V600E)-drug resistance by stressing mitochondria.
Luo C, Puigserver P, Widlund HR. Luo C, et al. Among authors: puigserver p. Pigment Cell Melanoma Res. 2016 Jul;29(4):401-3. doi: 10.1111/pcmr.12486. Pigment Cell Melanoma Res. 2016. PMID: 27135210 Free PMC article. No abstract available.
A PGC1α-mediated transcriptional axis suppresses melanoma metastasis.
Luo C, Lim JH, Lee Y, Granter SR, Thomas A, Vazquez F, Widlund HR, Puigserver P. Luo C, et al. Among authors: puigserver p. Nature. 2016 Sep 15;537(7620):422-426. doi: 10.1038/nature19347. Epub 2016 Aug 31. Nature. 2016. PMID: 27580028 Free PMC article.
136 results