Flotte T - Search Results

1

Engraftment of Human Hepatocytes in the PiZ-NSG Mouse Model.

Tang Q, Gernoux G, Cheng Y, Flotte T, Mueller C. Tang Q, et al. Among authors: flotte t. Methods Mol Biol. 2020;2164:75-85. doi: 10.1007/978-1-0716-0704-6_9. Methods Mol Biol. 2020. PMID: 32607885

2

Targeting recombinant adeno-associated virus vectors to enhance gene transfer to pancreatic islets and liver.

Loiler SA, Conlon TJ, Song S, Tang Q, Warrington KH, Agarwal A, Kapturczak M, Li C, Ricordi C, Atkinson MA, Muzyczka N, Flotte TR. Loiler SA, et al. Among authors: flotte tr. Gene Ther. 2003 Sep;10(18):1551-8. doi: 10.1038/sj.gt.3302046. Gene Ther. 2003. PMID: 12907946

3

Recombinant adeno-associated virus-mediated alpha-1 antitrypsin gene therapy prevents type I diabetes in NOD mice.

Song S, Goudy K, Campbell-Thompson M, Wasserfall C, Scott-Jorgensen M, Wang J, Tang Q, Crawford JM, Ellis TM, Atkinson MA, Flotte TR. Song S, et al. Among authors: flotte tr. Gene Ther. 2004 Jan;11(2):181-6. doi: 10.1038/sj.gt.3302156. Gene Ther. 2004. PMID: 14712302

4

DNA-dependent PK inhibits adeno-associated virus DNA integration.

Song S, Lu Y, Choi YK, Han Y, Tang Q, Zhao G, Berns KI, Flotte TR. Song S, et al. Proc Natl Acad Sci U S A. 2004 Feb 17;101(7):2112-6. doi: 10.1073/pnas.0307833100. Epub 2004 Feb 6. Proc Natl Acad Sci U S A. 2004. PMID: 14766968 Free PMC article.

5

Functional characterization of a recombinant adeno-associated virus 5-pseudotyped cystic fibrosis transmembrane conductance regulator vector.

Sirninger J, Muller C, Braag S, Tang Q, Yue H, Detrisac C, Ferkol T, Guggino WB, Flotte TR. Sirninger J, et al. Among authors: flotte tr. Hum Gene Ther. 2004 Sep;15(9):832-41. doi: 10.1089/hum.2004.15.832. Hum Gene Ther. 2004. PMID: 15353038

6

Localized gene expression following administration of adeno-associated viral vectors via pancreatic ducts.

Loiler SA, Tang Q, Clarke T, Campbell-Thompson ML, Chiodo V, Hauswirth W, Cruz P, Perret-Gentil M, Atkinson MA, Ramiya VK, Flotte TR. Loiler SA, et al. Among authors: flotte tr. Mol Ther. 2005 Sep;12(3):519-27. doi: 10.1016/j.ymthe.2005.04.017. Mol Ther. 2005. PMID: 15979413 Free article.

7

Therapeutic level of functional human alpha 1 antitrypsin (hAAT) secreted from murine muscle transduced by adeno-associated virus (rAAV1) vector.

Lu Y, Choi YK, Campbell-Thompson M, Li C, Tang Q, Crawford JM, Flotte TR, Song S. Lu Y, et al. J Gene Med. 2006 Jun;8(6):730-5. doi: 10.1002/jgm.896. J Gene Med. 2006. PMID: 16518879

8

In vivo post-transcriptional gene silencing of alpha-1 antitrypsin by adeno-associated virus vectors expressing siRNA.

Cruz PE, Mueller C, Cossette TL, Golant A, Tang Q, Beattie SG, Brantly M, Campbell-Thompson M, Blomenkamp KS, Teckman JH, Flotte TR. Cruz PE, et al. Lab Invest. 2007 Sep;87(9):893-902. doi: 10.1038/labinvest.3700629. Epub 2007 Jun 25. Lab Invest. 2007. PMID: 17592477 Free article.

9

The promise of gene therapy for the treatment of alpha-1 antitrypsin deficiency.

Cruz PE, Mueller C, Flotte TR. Cruz PE, et al. Pharmacogenomics. 2007 Sep;8(9):1191-8. doi: 10.2217/14622416.8.9.1191. Pharmacogenomics. 2007. PMID: 17924834 Review.

10

Partial correction of the CFTR-dependent ABPA mouse model with recombinant adeno-associated virus gene transfer of truncated CFTR gene.

Mueller C, Torrez D, Braag S, Martino A, Clarke T, Campbell-Thompson M, Flotte TR. Mueller C, et al. Among authors: flotte tr. J Gene Med. 2008 Jan;10(1):51-60. doi: 10.1002/jgm.1119. J Gene Med. 2008. PMID: 18023072

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