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Diamond Blackfan anemia is mediated by hyperactive Nemo-like kinase.
Wilkes MC, Siva K, Chen J, Varetti G, Youn MY, Chae H, Ek F, Olsson R, Lundbäck T, Dever DP, Nishimura T, Narla A, Glader B, Nakauchi H, Porteus MH, Repellin CE, Gazda HT, Lin S, Serrano M, Flygare J, Sakamoto KM. Wilkes MC, et al. Among authors: varetti g. Nat Commun. 2020 Jul 3;11(1):3344. doi: 10.1038/s41467-020-17100-z. Nat Commun. 2020. PMID: 32620751 Free PMC article.
Metformin-induced suppression of Nemo-like kinase improves erythropoiesis in preclinical models of Diamond-Blackfan anemia through induction of miR-26a.
Wilkes MC, Siva K, Varetti G, Mercado J, Wentworth EP, Perez CA, Saxena M, Kam S, Kapur S, Chen J, Narla A, Glader B, Lin S, Serrano M, Flygare J, Sakamoto KM. Wilkes MC, et al. Among authors: varetti g. Exp Hematol. 2020 Nov;91:65-77. doi: 10.1016/j.exphem.2020.09.187. Epub 2020 Sep 12. Exp Hematol. 2020. PMID: 32926965 Free PMC article.
Homeostatic control of mitotic arrest.
Varetti G, Guida C, Santaguida S, Chiroli E, Musacchio A. Varetti G, et al. Mol Cell. 2011 Dec 9;44(5):710-20. doi: 10.1016/j.molcel.2011.11.014. Mol Cell. 2011. PMID: 22152475 Free article.
The spindle assembly checkpoint.
Varetti G, Musacchio A. Varetti G, et al. Curr Biol. 2008 Jul 22;18(14):R591-5. doi: 10.1016/j.cub.2008.06.012. Curr Biol. 2008. PMID: 18644330 Free article. No abstract available.
Aurea mediocritas: the importance of a balanced genome.
Varetti G, Pellman D, Gordon DJ. Varetti G, et al. Cold Spring Harb Perspect Biol. 2014 Sep 18;6(11):a015842. doi: 10.1101/cshperspect.a015842. Cold Spring Harb Perspect Biol. 2014. PMID: 25237130 Free PMC article. Review.
18 results