Schones DE - Search Results

1

Dietary glutamine supplementation suppresses epigenetically-activated oncogenic pathways to inhibit melanoma tumour growth.

Ishak Gabra MB, Yang Y, Li H, Senapati P, Hanse EA, Lowman XH, Tran TQ, Zhang L, Doan LT, Xu X, Schones DE, Fruman DA, Kong M. Ishak Gabra MB, et al. Among authors: schones de. Nat Commun. 2020 Jul 3;11(1):3326. doi: 10.1038/s41467-020-17181-w. Nat Commun. 2020. PMID: 32620791 Free PMC article.

2

RUNX1 prevents oestrogen-mediated AXIN1 suppression and β-catenin activation in ER-positive breast cancer.

Chimge NO, Little GH, Baniwal SK, Adisetiyo H, Xie Y, Zhang T, O'Laughlin A, Liu ZY, Ulrich P, Martin A, Mhawech-Fauceglia P, Ellis MJ, Tripathy D, Groshen S, Liang C, Li Z, Schones DE, Frenkel B. Chimge NO, et al. Among authors: schones de. Nat Commun. 2016 Feb 26;7:10751. doi: 10.1038/ncomms10751. Nat Commun. 2016. PMID: 26916619 Free PMC article.

3

Regional glutamine deficiency in tumours promotes dedifferentiation through inhibition of histone demethylation.

Pan M, Reid MA, Lowman XH, Kulkarni RP, Tran TQ, Liu X, Yang Y, Hernandez-Davies JE, Rosales KK, Li H, Hugo W, Song C, Xu X, Schones DE, Ann DK, Gradinaru V, Lo RS, Locasale JW, Kong M. Pan M, et al. Among authors: schones de. Nat Cell Biol. 2016 Oct;18(10):1090-101. doi: 10.1038/ncb3410. Epub 2016 Sep 12. Nat Cell Biol. 2016. PMID: 27617932 Free PMC article.

4

Regulation of angiotensin II actions by enhancers and super-enhancers in vascular smooth muscle cells.

Das S, Senapati P, Chen Z, Reddy MA, Ganguly R, Lanting L, Mandi V, Bansal A, Leung A, Zhang S, Jia Y, Wu X, Schones DE, Natarajan R. Das S, et al. Among authors: schones de. Nat Commun. 2017 Nov 13;8(1):1467. doi: 10.1038/s41467-017-01629-7. Nat Commun. 2017. PMID: 29133788 Free PMC article.

5

Diabetes Mellitus-Induced Long Noncoding RNA Dnm3os Regulates Macrophage Functions and Inflammation via Nuclear Mechanisms.

Das S, Reddy MA, Senapati P, Stapleton K, Lanting L, Wang M, Amaram V, Ganguly R, Zhang L, Devaraj S, Schones DE, Natarajan R. Das S, et al. Among authors: schones de. Arterioscler Thromb Vasc Biol. 2018 Aug;38(8):1806-1820. doi: 10.1161/ATVBAHA.117.310663. Arterioscler Thromb Vasc Biol. 2018. PMID: 29930005 Free PMC article.

6

Hyperinsulinemia promotes aberrant histone acetylation in triple-negative breast cancer.

Senapati P, Kato H, Lee M, Leung A, Thai C, Sanchez A, Gallagher EJ, LeRoith D, Seewaldt VL, Ann DK, Schones DE. Senapati P, et al. Among authors: schones de. Epigenetics Chromatin. 2019 Jul 17;12(1):44. doi: 10.1186/s13072-019-0290-9. Epigenetics Chromatin. 2019. PMID: 31315653 Free PMC article.

7

Loss of epigenetic suppression of retrotransposons with oncogenic potential in aging mammary luminal epithelial cells.

Senapati P, Miyano M, Sayaman RW, Basam M, Leung A, LaBarge MA, Schones DE. Senapati P, et al. Among authors: schones de. Genome Res. 2023 Aug;33(8):1229-1241. doi: 10.1101/gr.277511.122. Epub 2023 Jul 18. Genome Res. 2023. PMID: 37463750 Free PMC article.

8

Inhibition of DNMT1 methyltransferase activity via glucose-regulated O-GlcNAcylation alters the epigenome.

Shin H, Leung A, Costello KR, Senapati P, Kato H, Moore RE, Lee M, Lin D, Tang X, Pirrotte P, Bouman Chen Z, Schones DE. Shin H, et al. Among authors: schones de. Elife. 2023 Jul 20;12:e85595. doi: 10.7554/eLife.85595. Elife. 2023. PMID: 37470704 Free PMC article.

9

LTRs activated by Epstein-Barr virus-induced transformation of B cells alter the transcriptome.

Leung A, Trac C, Kato H, Costello KR, Chen Z, Natarajan R, Schones DE. Leung A, et al. Among authors: schones de. Genome Res. 2018 Dec;28(12):1791-1798. doi: 10.1101/gr.233585.117. Epub 2018 Oct 31. Genome Res. 2018. PMID: 30381291 Free PMC article.

10

Arginine starvation kills tumor cells through aspartate exhaustion and mitochondrial dysfunction.

Cheng CT, Qi Y, Wang YC, Chi KK, Chung Y, Ouyang C, Chen YR, Oh ME, Sheng X, Tang Y, Liu YR, Lin HH, Kuo CY, Schones D, Vidal CM, Chu JC, Wang HJ, Chen YH, Miller KM, Chu P, Yen Y, Jiang L, Kung HJ, Ann DK. Cheng CT, et al. Commun Biol. 2018 Oct 26;1:178. doi: 10.1038/s42003-018-0178-4. eCollection 2018. Commun Biol. 2018. PMID: 30393775 Free PMC article.

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