Yang Y - Search Results

1

Dietary glutamine supplementation suppresses epigenetically-activated oncogenic pathways to inhibit melanoma tumour growth.

Ishak Gabra MB, Yang Y, Li H, Senapati P, Hanse EA, Lowman XH, Tran TQ, Zhang L, Doan LT, Xu X, Schones DE, Fruman DA, Kong M. Ishak Gabra MB, et al. Among authors: yang y. Nat Commun. 2020 Jul 3;11(1):3326. doi: 10.1038/s41467-020-17181-w. Nat Commun. 2020. PMID: 32620791 Free PMC article.

2

Vemurafenib resistance reprograms melanoma cells towards glutamine dependence.

Hernandez-Davies JE, Tran TQ, Reid MA, Rosales KR, Lowman XH, Pan M, Moriceau G, Yang Y, Wu J, Lo RS, Kong M. Hernandez-Davies JE, et al. Among authors: yang y. J Transl Med. 2015 Jul 3;13:210. doi: 10.1186/s12967-015-0581-2. J Transl Med. 2015. PMID: 26139106 Free PMC article.

3

TIPRL Inhibits Protein Phosphatase 4 Activity and Promotes H2AX Phosphorylation in the DNA Damage Response.

Rosales KR, Reid MA, Yang Y, Tran TQ, Wang WI, Lowman X, Pan M, Kong M. Rosales KR, et al. Among authors: yang y. PLoS One. 2015 Dec 30;10(12):e0145938. doi: 10.1371/journal.pone.0145938. eCollection 2015. PLoS One. 2015. PMID: 26717153 Free PMC article.

4

IKKβ promotes metabolic adaptation to glutamine deprivation via phosphorylation and inhibition of PFKFB3.

Reid MA, Lowman XH, Pan M, Tran TQ, Warmoes MO, Ishak Gabra MB, Yang Y, Locasale JW, Kong M. Reid MA, et al. Among authors: yang y. Genes Dev. 2016 Aug 15;30(16):1837-51. doi: 10.1101/gad.287235.116. Epub 2016 Sep 1. Genes Dev. 2016. PMID: 27585591 Free PMC article.

5

Regional glutamine deficiency in tumours promotes dedifferentiation through inhibition of histone demethylation.

Pan M, Reid MA, Lowman XH, Kulkarni RP, Tran TQ, Liu X, Yang Y, Hernandez-Davies JE, Rosales KK, Li H, Hugo W, Song C, Xu X, Schones DE, Ann DK, Gradinaru V, Lo RS, Locasale JW, Kong M. Pan M, et al. Among authors: yang y. Nat Cell Biol. 2016 Oct;18(10):1090-101. doi: 10.1038/ncb3410. Epub 2016 Sep 12. Nat Cell Biol. 2016. PMID: 27617932 Free PMC article.

6

Glutamine deficiency induces DNA alkylation damage and sensitizes cancer cells to alkylating agents through inhibition of ALKBH enzymes.

Tran TQ, Ishak Gabra MB, Lowman XH, Yang Y, Reid MA, Pan M, O'Connor TR, Kong M. Tran TQ, et al. Among authors: yang y. PLoS Biol. 2017 Nov 6;15(11):e2002810. doi: 10.1371/journal.pbio.2002810. eCollection 2017 Nov. PLoS Biol. 2017. PMID: 29107960 Free PMC article.

7

CARM1 suppresses de novo serine synthesis by promoting PKM2 activity.

Abeywardana T, Oh M, Jiang L, Yang Y, Kong M, Song J, Yang Y. Abeywardana T, et al. Among authors: yang y. J Biol Chem. 2018 Sep 28;293(39):15290-15303. doi: 10.1074/jbc.RA118.004512. Epub 2018 Aug 21. J Biol Chem. 2018. PMID: 30131339 Free PMC article.

8

IKKβ activates p53 to promote cancer cell adaptation to glutamine deprivation.

Ishak Gabra MB, Yang Y, Lowman XH, Reid MA, Tran TQ, Kong M. Ishak Gabra MB, et al. Among authors: yang y. Oncogenesis. 2018 Nov 26;7(11):93. doi: 10.1038/s41389-018-0104-0. Oncogenesis. 2018. PMID: 30478303 Free PMC article.

9

NADP⁺ is an endogenous PARP inhibitor in DNA damage response and tumor suppression.

Bian C, Zhang C, Luo T, Vyas A, Chen SH, Liu C, Kassab MA, Yang Y, Kong M, Yu X. Bian C, et al. Among authors: yang y. Nat Commun. 2019 Feb 11;10(1):693. doi: 10.1038/s41467-019-08530-5. Nat Commun. 2019. PMID: 30741937 Free PMC article.

10

MiR-135 suppresses glycolysis and promotes pancreatic cancer cell adaptation to metabolic stress by targeting phosphofructokinase-1.

Yang Y, Ishak Gabra MB, Hanse EA, Lowman XH, Tran TQ, Li H, Milman N, Liu J, Reid MA, Locasale JW, Gil Z, Kong M. Yang Y, et al. Nat Commun. 2019 Feb 18;10(1):809. doi: 10.1038/s41467-019-08759-0. Nat Commun. 2019. PMID: 30778058 Free PMC article.

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