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Transcription factor MafB in podocytes protects against the development of focal segmental glomerulosclerosis.
Usui T, Morito N, Shawki HH, Sato Y, Tsukaguchi H, Hamada M, Jeon H, Yadav MK, Kuno A, Tsunakawa Y, Okada R, Ojima T, Kanai M, Asano K, Imamura Y, Koshida R, Yoh K, Usui J, Yokoi H, Kasahara M, Yoshimura A, Muratani M, Kudo T, Oishi H, Yamagata K, Takahashi S. Usui T, et al. Among authors: usui j. Kidney Int. 2020 Aug;98(2):391-403. doi: 10.1016/j.kint.2020.02.038. Epub 2020 Apr 28. Kidney Int. 2020. PMID: 32622525 Free article.
Two autosomal dominant polycystic kidney (ADPKD) cases with advanced renal dysfunction, effectively treated with tolvaptan.
Kai H, Shinozaki Y, Nishikubo A, Watanabe M, Tawara T, Iwase M, Tsunoda R, Moriyama N, Usui T, Kawamura T, Nagai K, Hagiwara M, Saito C, Morito N, Usui J, Yamagata K. Kai H, et al. Among authors: usui t, usui j. CEN Case Rep. 2016 May;5(1):87-90. doi: 10.1007/s13730-015-0198-6. Epub 2015 Nov 17. CEN Case Rep. 2016. PMID: 28509176 Free PMC article.
MafB is a critical regulator of complement component C1q.
Tran MTN, Hamada M, Jeon H, Shiraishi R, Asano K, Hattori M, Nakamura M, Imamura Y, Tsunakawa Y, Fujii R, Usui T, Kulathunga K, Andrea CS, Koshida R, Kamei R, Matsunaga Y, Kobayashi M, Oishi H, Kudo T, Takahashi S. Tran MTN, et al. Among authors: usui t. Nat Commun. 2017 Nov 22;8(1):1700. doi: 10.1038/s41467-017-01711-0. Nat Commun. 2017. PMID: 29167450 Free PMC article.
A mutation in transcription factor MAFB causes Focal Segmental Glomerulosclerosis with Duane Retraction Syndrome.
Sato Y, Tsukaguchi H, Morita H, Higasa K, Tran MTN, Hamada M, Usui T, Morito N, Horita S, Hayashi T, Takagi J, Yamaguchi I, Nguyen HT, Harada M, Inui K, Maruta Y, Inoue Y, Koiwa F, Sato H, Matsuda F, Ayabe S, Mizuno S, Sugiyama F, Takahashi S, Yoshimura A. Sato Y, et al. Among authors: usui t. Kidney Int. 2018 Aug;94(2):396-407. doi: 10.1016/j.kint.2018.02.025. Epub 2018 May 18. Kidney Int. 2018. PMID: 29779709 Free article.
Phenotypic analysis of mice carrying human-type MAFB p.Leu239Pro mutation.
Kanai M, Jeon H, Ojima M, Nishino T, Usui T, Yadav MK, Kulathunga K, Morito N, Takahashi S, Hamada M. Kanai M, et al. Among authors: usui t. Biochem Biophys Res Commun. 2020 Mar 5;523(2):452-457. doi: 10.1016/j.bbrc.2019.12.033. Epub 2019 Dec 25. Biochem Biophys Res Commun. 2020. PMID: 31882119
Mice lacking core 1-derived O-glycan in podocytes develop transient proteinuria, resulting in focal segmental glomerulosclerosis.
Fuseya S, Suzuki R, Okada R, Hagiwara K, Sato T, Narimatsu H, Yokoi H, Kasahara M, Usui T, Morito N, Yamagata K, Kudo T, Takahashi S. Fuseya S, et al. Among authors: usui t. Biochem Biophys Res Commun. 2020 Mar 19;523(4):1007-1013. doi: 10.1016/j.bbrc.2020.01.033. Epub 2020 Jan 20. Biochem Biophys Res Commun. 2020. PMID: 31973821
1,944 results