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Scientific Opinion of Flavouring Group Evaluation 406 (FGE.406): (S)-1-(3-(((4-amino-2,2-dioxido-1H-benzo[c][1,2,6]thiadiazin-5-yl)oxy)methyl)piperidin-1-yl)-3-methylbutan-1-one.
EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF); Silano V, Bolognesi C, Castle L, Chipman K, Cravedi JP, Engel KH, Fowler P, Franz R, Grob K, Gürtler R, Husøy T, Kärenlampi S, Milana MR, Pfaff K, Riviere G, Srinivasan J, Tavares Poças MF, Tlustos C, Wölfle D, Zorn H, Beckman Sundh U, Benigni R, Binderup ML, Brimer L, Marcon F, Marzin D, Mosesso P, Mulder G, Oskarsson A, Svendsen C, Van Benthem J, Anastassiadou M, Carfì M, Mennes W. EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF), et al. Among authors: van benthem j. EFSA J. 2018 Feb 23;16(2):e05120. doi: 10.2903/j.efsa.2018.5120. eCollection 2018 Feb. EFSA J. 2018. PMID: 32625796 Free PMC article.
Scientific Opinion of Flavouring Group Evaluation 411 (FGE.411): 2-(4-methylphenoxy)-N-(1H-pyrazol-3-yl)-N-(thiophen-2-ylmethyl)acetamide from chemical group 30 (miscellaneous substances).
EFSA Panel on Food Additives and Flavourings (FAF); Younes M, Aquilina G, Castle L, Engel KH, Fowler P, Frutos Fernandez MJ, Fürst P, Gundert-Remy U, Gürtler R, Husøy T, Moldeus P, Oskarsson A, Rainieri S, Shah R, Waalkens-Berendsen I, Wölfle D, Benigni R, Binderup ML, Bolognesi C, Brimer L, Chipman K, Marcon F, Marzin D, Mosesso P, Mulder G, Svendsen C, van Benthem J, Anastassiadou M, Carfí M, Mennes W. EFSA Panel on Food Additives and Flavourings (FAF), et al. Among authors: van benthem j. EFSA J. 2018 Oct 19;16(10):e05421. doi: 10.2903/j.efsa.2018.5421. eCollection 2018 Oct. EFSA J. 2018. PMID: 32625706 Free PMC article.
Scientific Opinion on Flavouring Group Evaluation 74, Revision 4 (FGE.74Rev4): Consideration of aliphatic sulphides and thiols evaluated by JECFA (53rd and 61st meeting) structurally related to aliphatic and alicyclic mono-, di-, tri- and polysulphides with or without additional oxygenated functional groups from chemical group 20 evaluated by EFSA in FGE.08Rev5.
EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF); Silano V, Bolognesi C, Castle L, Chipman K, Cravedi JP, Engel KH, Fowler P, Franz R, Grob K, Gürtler R, Husøy T, Kärenlampi S, Milana MR, Pfaff K, Riviere G, Srinivasan J, Tavares Poças MF, Tlustos C, Wölfle D, Zorn H, Benigni R, Brimer L, Mulder G, Oskarsson A, Svendsen C, van Benthem J, Anastassiadou M, Saarma S, Mennes W. EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF), et al. Among authors: van benthem j. EFSA J. 2018 Mar 20;16(3):e05167. doi: 10.2903/j.efsa.2018.5167. eCollection 2018 Mar. EFSA J. 2018. PMID: 32625823 Free PMC article.
Scientific opinion on flavouring group evaluation 77, revision 3 (FGE.77Rev3): consideration of pyridine, pyrrole and quinoline derivatives evaluated by JECFA (63rd meeting) structurally related to pyridine, pyrrole, indole and quinoline derivatives evaluated by EFSA in FGE.24Rev2.
EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF); Silano V, Bolognesi C, Castle L, Chipman K, Cravedi JP, Engel KH, Fowler P, Franz R, Grob K, Gürtler R, Husøy T, Kärenlampi S, Milana MR, Pfaff K, Riviere G, Srinivasan J, Tavares Poças MF, Tlustos C, Wölfle D, Zorn H, Benigni R, Binderup ML, Brimer L, Marcon F, Marzin D, Mosesso P, Mulder G, Oskarsson A, Svendsen C, van Benthem J, Anastassiadou M, Carfì M, Mennes W. EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF), et al. Among authors: van benthem j. EFSA J. 2018 Apr 25;16(4):e05226. doi: 10.2903/j.efsa.2018.5226. eCollection 2018 Apr. EFSA J. 2018. PMID: 32625865 Free PMC article.
Clarification of some aspects related to genotoxicity assessment.
EFSA Scientific Committee; Hardy A, Benford D, Halldorsson T, Jeger M, Knutsen HK, More S, Naegeli H, Noteborn H, Ockleford C, Ricci A, Rychen G, Silano V, Solecki R, Turck D, Younes M, Aquilina G, Crebelli R, Gürtler R, Hirsch-Ernst KI, Mosesso P, Nielsen E, van Benthem J, Carfì M, Georgiadis N, Maurici D, Parra Morte J, Schlatter J. EFSA Scientific Committee, et al. Among authors: van benthem j. EFSA J. 2017 Dec 18;15(12):e05113. doi: 10.2903/j.efsa.2017.5113. eCollection 2017 Dec. EFSA J. 2017. PMID: 32625393 Free PMC article.
ECVAM retrospective validation of in vitro micronucleus test (MNT).
Corvi R, Albertini S, Hartung T, Hoffmann S, Maurici D, Pfuhler S, van Benthem J, Vanparys P. Corvi R, et al. Among authors: van benthem j. Mutagenesis. 2008 Jul;23(4):271-83. doi: 10.1093/mutage/gen010. Epub 2008 Mar 7. Mutagenesis. 2008. PMID: 18326866 Free PMC article.
Strategies in case of positive in vivo results in genotoxicity testing.
Thybaud V, Macgregor JT, Müller L, Crebelli R, Dearfield K, Douglas G, Farmer PB, Gocke E, Hayashi M, Lovell DP, Lutz WK, Marzin D, Moore M, Nohmi T, Phillips DH, Van Benthem J. Thybaud V, et al. Among authors: van benthem j. Mutat Res. 2011 Aug 16;723(2):121-8. doi: 10.1016/j.mrgentox.2010.09.002. Epub 2010 Sep 17. Mutat Res. 2011. PMID: 20854927
How to reduce false positive results when undertaking in vitro genotoxicity testing and thus avoid unnecessary follow-up animal tests: Report of an ECVAM Workshop.
Kirkland D, Pfuhler S, Tweats D, Aardema M, Corvi R, Darroudi F, Elhajouji A, Glatt H, Hastwell P, Hayashi M, Kasper P, Kirchner S, Lynch A, Marzin D, Maurici D, Meunier JR, Müller L, Nohynek G, Parry J, Parry E, Thybaud V, Tice R, van Benthem J, Vanparys P, White P. Kirkland D, et al. Among authors: van benthem j. Mutat Res. 2007 Mar 30;628(1):31-55. doi: 10.1016/j.mrgentox.2006.11.008. Epub 2007 Jan 13. Mutat Res. 2007. PMID: 17293159
Can in vitro mammalian cell genotoxicity test results be used to complement positive results in the Ames test and help predict carcinogenic or in vivo genotoxic activity? I. Reports of individual databases presented at an EURL ECVAM Workshop.
Kirkland D, Zeiger E, Madia F, Gooderham N, Kasper P, Lynch A, Morita T, Ouedraogo G, Parra Morte JM, Pfuhler S, Rogiers V, Schulz M, Thybaud V, van Benthem J, Vanparys P, Worth A, Corvi R. Kirkland D, et al. Among authors: van benthem j. Mutat Res Genet Toxicol Environ Mutagen. 2014 Dec;775-776:55-68. doi: 10.1016/j.mrgentox.2014.10.005. Epub 2014 Oct 23. Mutat Res Genet Toxicol Environ Mutagen. 2014. PMID: 25435356 Free article.
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