Martin-Requero Á - Search Results

1

Therapeutic potential of novel Cell Division Cycle Kinase 7 inhibitors on TDP-43-related pathogenesis such as Frontotemporal Lobar Degeneration (FTLD) and amyotrophic lateral sclerosis (ALS).

Vaca G, Martinez-Gonzalez L, Fernandez A, Rojas-Prats E, Porras G, Cuevas EP, Gil C, Martinez A, Martin-Requero Á. Vaca G, et al. J Neurochem. 2021 Feb;156(3):379-390. doi: 10.1111/jnc.15118. Epub 2020 Jul 17. J Neurochem. 2021. PMID: 32628315 Free article.

2

Alteration in cell cycle-related proteins in lymphoblasts from carriers of the c.709-1G>A PGRN mutation associated with FTLD-TDP dementia.

Alquezar C, Esteras N, Bartolomé F, Merino JJ, Alzualde A, López de Munain A, Martín-Requero Á. Alquezar C, et al. Neurobiol Aging. 2012 Feb;33(2):429.e7-20. doi: 10.1016/j.neurobiolaging.2010.11.020. Epub 2011 Jan 12. Neurobiol Aging. 2012. PMID: 21232819 Free article.

3

Inactivation of CDK/pRb pathway normalizes survival pattern of lymphoblasts expressing the FTLD-progranulin mutation c.709-1G>A.

Alquezar C, Esteras N, Alzualde A, Moreno F, Ayuso MS, López de Munain A, Martín-Requero Á. Alquezar C, et al. PLoS One. 2012;7(5):e37057. doi: 10.1371/journal.pone.0037057. Epub 2012 May 18. PLoS One. 2012. PMID: 22623979 Free PMC article.

4

PGRN haploinsufficiency increased Wnt5a signaling in peripheral cells from frontotemporal lobar degeneration-progranulin mutation carriers.

Alquézar C, Esteras N, de la Encarnación A, Alzualde A, Moreno F, López de Munain A, Martín-Requero A. Alquézar C, et al. Neurobiol Aging. 2014 Apr;35(4):886-98. doi: 10.1016/j.neurobiolaging.2013.09.021. Epub 2013 Oct 16. Neurobiol Aging. 2014. PMID: 24139281 Free article.

5

Increasing progranulin levels and blockade of the ERK1/2 pathway: upstream and downstream strategies for the treatment of progranulin deficient frontotemporal dementia.

Alquezar C, Esteras N, de la Encarnación A, Moreno F, López de Munain A, Martín-Requero Á. Alquezar C, et al. Eur Neuropsychopharmacol. 2015 Mar;25(3):386-403. doi: 10.1016/j.euroneuro.2014.12.007. Epub 2015 Jan 5. Eur Neuropsychopharmacol. 2015. PMID: 25624003

6

Targeting cyclin D3/CDK6 activity for treatment of Parkinson's disease.

Alquézar C, Barrio E, Esteras N, de la Encarnación A, Bartolomé F, Molina JA, Martín-Requero Á. Alquézar C, et al. J Neurochem. 2015 Jun;133(6):886-97. doi: 10.1111/jnc.13070. Epub 2015 Mar 15. J Neurochem. 2015. PMID: 25689470 Free article.

7

Progranulin deficiency induces overactivation of WNT5A expression via TNF-α/NF-κB pathway in peripheral cells from frontotemporal dementia-linked granulin mutation carriers.

Alquézar C, de la Encarnación A, Moreno F, López de Munain A, Martín-Requero Á. Alquézar C, et al. J Psychiatry Neurosci. 2016 Jun;41(4):225-39. doi: 10.1503/jpn.150131. J Psychiatry Neurosci. 2016. PMID: 26624524 Free PMC article.

8

Increased Wnt Signaling and Reduced Viability in a Neuronal Model of Progranulin-Deficient Frontotemporal Lobar Degeneration.

de la Encarnación A, Alquézar C, Martín-Requero Á. de la Encarnación A, et al. Mol Neurobiol. 2016 Dec;53(10):7107-7118. doi: 10.1007/s12035-015-9596-1. Epub 2015 Dec 17. Mol Neurobiol. 2016. PMID: 26676574

9

Targeting TDP-43 phosphorylation by Casein Kinase-1δ inhibitors: a novel strategy for the treatment of frontotemporal dementia.

Alquezar C, Salado IG, de la Encarnación A, Pérez DI, Moreno F, Gil C, de Munain AL, Martínez A, Martín-Requero Á. Alquezar C, et al. Mol Neurodegener. 2016 Apr 30;11(1):36. doi: 10.1186/s13024-016-0102-7. Mol Neurodegener. 2016. PMID: 27138926 Free PMC article.

10

Recapitulation of Pathological TDP-43 Features in Immortalized Lymphocytes from Sporadic ALS Patients.

Posa D, Martínez-González L, Bartolomé F, Nagaraj S, Porras G, Martínez A, Martín-Requero Á. Posa D, et al. Mol Neurobiol. 2019 Apr;56(4):2424-2432. doi: 10.1007/s12035-018-1249-8. Epub 2018 Jul 20. Mol Neurobiol. 2019. PMID: 30030753

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

78 results

Search Page

Filters