Porras G - Search Results

1

Therapeutic potential of novel Cell Division Cycle Kinase 7 inhibitors on TDP-43-related pathogenesis such as Frontotemporal Lobar Degeneration (FTLD) and amyotrophic lateral sclerosis (ALS).

Vaca G, Martinez-Gonzalez L, Fernandez A, Rojas-Prats E, Porras G, Cuevas EP, Gil C, Martinez A, Martin-Requero Á. Vaca G, et al. Among authors: porras g. J Neurochem. 2021 Feb;156(3):379-390. doi: 10.1111/jnc.15118. Epub 2020 Jul 17. J Neurochem. 2021. PMID: 32628315 Free article.

2

Recapitulation of Pathological TDP-43 Features in Immortalized Lymphocytes from Sporadic ALS Patients.

Posa D, Martínez-González L, Bartolomé F, Nagaraj S, Porras G, Martínez A, Martín-Requero Á. Posa D, et al. Among authors: porras g. Mol Neurobiol. 2019 Apr;56(4):2424-2432. doi: 10.1007/s12035-018-1249-8. Epub 2018 Jul 20. Mol Neurobiol. 2019. PMID: 30030753

3

CdSe Quantum Dots in Human Models Derived from ALS Patients: Characterization, Nuclear Penetration Studies and Multiplexing.

Tosat-Bitrián C, Avis-Bodas A, Porras G, Borrego-Hernández D, García-Redondo A, Martín-Requero A, Palomo V. Tosat-Bitrián C, et al. Among authors: porras g. Nanomaterials (Basel). 2021 Mar 9;11(3):671. doi: 10.3390/nano11030671. Nanomaterials (Basel). 2021. PMID: 33803158 Free PMC article.

4

Molecular Alterations in Sporadic and SOD1-ALS Immortalized Lymphocytes: Towards a Personalized Therapy.

Lastres-Becker I, Porras G, Arribas-Blázquez M, Maestro I, Borrego-Hernández D, Boya P, Cerdán S, García-Redondo A, Martínez A, Martin-Requero Á. Lastres-Becker I, et al. Among authors: porras g. Int J Mol Sci. 2021 Mar 16;22(6):3007. doi: 10.3390/ijms22063007. Int J Mol Sci. 2021. PMID: 33809456 Free PMC article.

5

Tideglusib, a Non-ATP Competitive Inhibitor of GSK-3β as a Drug Candidate for the Treatment of Amyotrophic Lateral Sclerosis.

Martínez-González L, Gonzalo-Consuegra C, Gómez-Almería M, Porras G, de Lago E, Martín-Requero Á, Martínez A. Martínez-González L, et al. Among authors: porras g. Int J Mol Sci. 2021 Aug 20;22(16):8975. doi: 10.3390/ijms22168975. Int J Mol Sci. 2021. PMID: 34445680 Free PMC article.

6

Multitarget Hybrid Fasudil Derivatives as a New Approach to the Potential Treatment of Amyotrophic Lateral Sclerosis.

Martín-Cámara O, Arribas M, Wells G, Morales-Tenorio M, Martín-Requero Á, Porras G, Martínez A, Giorgi G, López-Alvarado P, Lastres-Becker I, Menéndez JC. Martín-Cámara O, et al. Among authors: porras g. J Med Chem. 2022 Feb 10;65(3):1867-1882. doi: 10.1021/acs.jmedchem.1c01255. Epub 2022 Jan 5. J Med Chem. 2022. PMID: 34985276 Free PMC article.

7

Discovery of Mitophagy Inhibitors with Therapeutic Potential in Different Familial Amyotrophic Lateral Sclerosis Mutations.

Maestro I, de la Ballina LR, Porras G, Corrochano S, De Lago E, Simonsen A, Boya P, Martinez A. Maestro I, et al. Among authors: porras g. Int J Mol Sci. 2022 Oct 21;23(20):12676. doi: 10.3390/ijms232012676. Int J Mol Sci. 2022. PMID: 36293534 Free PMC article.

8

Functional Characterization of a Familial ALS-Associated Missense TBK1 (p-Arg573Gly) Mutation in Patient-Derived Lymphoblasts.

Porras G, Ruiz S, Maestro I, Borrego-Hernández D, Redondo AG, Martínez A, Martín-Requero Á. Porras G, et al. Int J Mol Sci. 2023 Feb 2;24(3):2847. doi: 10.3390/ijms24032847. Int J Mol Sci. 2023. PMID: 36769169 Free PMC article.

9

Proteome Aggregation in Cells Derived from Amyotrophic Lateral Sclerosis Patients for Personalized Drug Evaluation.

Pérez de la Lastra Aranda C, Tosat-Bitrián C, Porras G, Dafinca R, Muñoz-Torrero D, Talbot K, Martín-Requero Á, Martínez A, Palomo V. Pérez de la Lastra Aranda C, et al. Among authors: porras g. ACS Chem Neurosci. 2024 Nov 6;15(21):3945-3953. doi: 10.1021/acschemneuro.4c00328. Epub 2024 Oct 14. ACS Chem Neurosci. 2024. PMID: 39401249

10

Regulation of the mhp cluster responsible for 3-(3-hydroxyphenyl)propionic acid degradation in Escherichia coli.

Torres B, Porras G, Garcia JL, Diaz E. Torres B, et al. Among authors: porras g. J Biol Chem. 2003 Jul 25;278(30):27575-85. doi: 10.1074/jbc.M303245200. Epub 2003 May 13. J Biol Chem. 2003. PMID: 12748194 Free article.

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