Roberts CWM - Search Results

1

Rhabdoid Tumors Are Sensitive to the Protein-Translation Inhibitor Homoharringtonine.

Howard TP, Oberlick EM, Rees MG, Arnoff TE, Pham MT, Brenan L, DoCarmo M, Hong AL, Kugener G, Chou HC, Drosos Y, Mathias KM, Ramos P, Seashore-Ludlow B, Giacomelli AO, Wang X, Freeman BB 3rd, Blankenship K, Hoffmann L, Tiv HL, Gokhale PC, Johannessen CM, Stewart EA, Schreiber SL, Hahn WC, Roberts CWM. Howard TP, et al. Among authors: roberts cwm. Clin Cancer Res. 2020 Sep 15;26(18):4995-5006. doi: 10.1158/1078-0432.CCR-19-2717. Epub 2020 Jul 6. Clin Cancer Res. 2020. PMID: 32631955 Free PMC article.

2

The role of INI1 and the SWI/SNF complex in the development of rhabdoid tumors: meeting summary from the workshop on childhood atypical teratoid/rhabdoid tumors.

Biegel JA, Kalpana G, Knudsen ES, Packer RJ, Roberts CW, Thiele CJ, Weissman B, Smith M. Biegel JA, et al. Cancer Res. 2002 Jan 1;62(1):323-8. Cancer Res. 2002. PMID: 11782395

3

Molecular pathways: SWI/SNF (BAF) complexes are frequently mutated in cancer--mechanisms and potential therapeutic insights.

Wang X, Haswell JR, Roberts CW. Wang X, et al. Clin Cancer Res. 2014 Jan 1;20(1):21-7. doi: 10.1158/1078-0432.CCR-13-0280. Epub 2013 Oct 11. Clin Cancer Res. 2014. PMID: 24122795 Free PMC article.

4

Residual complexes containing SMARCA2 (BRM) underlie the oncogenic drive of SMARCA4 (BRG1) mutation.

Wilson BG, Helming KC, Wang X, Kim Y, Vazquez F, Jagani Z, Hahn WC, Roberts CW. Wilson BG, et al. Mol Cell Biol. 2014 Mar;34(6):1136-44. doi: 10.1128/MCB.01372-13. Epub 2014 Jan 13. Mol Cell Biol. 2014. PMID: 24421395 Free PMC article.

5

CARMA: CARM1 methylation of SWI/SNF in breast cancer.

Wang X, Roberts CW. Wang X, et al. Cancer Cell. 2014 Jan 13;25(1):3-4. doi: 10.1016/j.ccr.2013.12.017. Cancer Cell. 2014. PMID: 24434203 Free PMC article.

6

ARID1B is a specific vulnerability in ARID1A-mutant cancers.

Helming KC, Wang X, Wilson BG, Vazquez F, Haswell JR, Manchester HE, Kim Y, Kryukov GV, Ghandi M, Aguirre AJ, Jagani Z, Wang Z, Garraway LA, Hahn WC, Roberts CW. Helming KC, et al. Nat Med. 2014 Mar;20(3):251-4. doi: 10.1038/nm.3480. Epub 2014 Feb 23. Nat Med. 2014. PMID: 24562383 Free PMC article.

7

Mechanisms by which SMARCB1 loss drives rhabdoid tumor growth.

Kim KH, Roberts CW. Kim KH, et al. Cancer Genet. 2014 Sep;207(9):365-72. doi: 10.1016/j.cancergen.2014.04.004. Epub 2014 Apr 13. Cancer Genet. 2014. PMID: 24853101 Free PMC article. Review.

8

Vulnerabilities of mutant SWI/SNF complexes in cancer.

Helming KC, Wang X, Roberts CWM. Helming KC, et al. Among authors: roberts cwm. Cancer Cell. 2014 Sep 8;26(3):309-317. doi: 10.1016/j.ccr.2014.07.018. Cancer Cell. 2014. PMID: 25203320 Free PMC article. Review.

9

SWI/SNF-mutant cancers depend on catalytic and non-catalytic activity of EZH2.

Kim KH, Kim W, Howard TP, Vazquez F, Tsherniak A, Wu JN, Wang W, Haswell JR, Walensky LD, Hahn WC, Orkin SH, Roberts CW. Kim KH, et al. Nat Med. 2015 Dec;21(12):1491-6. doi: 10.1038/nm.3968. Epub 2015 Nov 9. Nat Med. 2015. PMID: 26552009 Free PMC article.

10

Atypical teratoid/rhabdoid tumors-current concepts, advances in biology, and potential future therapies.

Frühwald MC, Biegel JA, Bourdeaut F, Roberts CW, Chi SN. Frühwald MC, et al. Neuro Oncol. 2016 Jun;18(6):764-78. doi: 10.1093/neuonc/nov264. Epub 2016 Jan 10. Neuro Oncol. 2016. PMID: 26755072 Free PMC article. Review.

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