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Page 1
Inhibition and Crystal Structure of the Human DHTKD1-Thiamin Diphosphate Complex.
Leandro J, Khamrui S, Wang H, Suebsuwong C, Nemeria NS, Huynh K, Moustakim M, Secor C, Wang M, Dodatko T, Stauffer B, Wilson CG, Yu C, Arkin MR, Jordan F, Sanchez R, DeVita RJ, Lazarus MB, Houten SM. Leandro J, et al. Among authors: jordan f. ACS Chem Biol. 2020 Aug 21;15(8):2041-2047. doi: 10.1021/acschembio.0c00114. Epub 2020 Jul 9. ACS Chem Biol. 2020. PMID: 32633484 Free PMC article.
2-Oxo-3-alkynoic acids, universal mechanism-based inactivators of thiamin diphosphate-dependent decarboxylases: synthesis and evidence for potent inactivation of the pyruvate dehydrogenase multienzyme complex.
Brown A, Nemeria N, Yi J, Zhang D, Jordan WB, Machado RS, Guest JR, Jordan F. Brown A, et al. Among authors: jordan wb, jordan f. Biochemistry. 1997 Jul 1;36(26):8071-81. doi: 10.1021/bi970094y. Biochemistry. 1997. PMID: 9201955
A new class of compounds, the 2-oxo-3-alkynoic acids with a phenyl substituent at carbon 4 was reported by the authors as potent irreversible and mechanism-based inhibitors of the thiamin diphosphate- (ThDP-) dependent enzyme pyruvate decarboxylase [Chiu, C.-F., & J
A new class of compounds, the 2-oxo-3-alkynoic acids with a phenyl substituent at carbon 4 was reported by the authors as potent irreversibl …
Inhibition of the Escherichia coli pyruvate dehydrogenase complex E1 subunit and its tyrosine 177 variants by thiamin 2-thiazolone and thiamin 2-thiothiazolone diphosphates. Evidence for reversible tight-binding inhibition.
Nemeria N, Yan Y, Zhang Z, Brown AM, Arjunan P, Furey W, Guest JR, Jordan F. Nemeria N, et al. Among authors: jordan f. J Biol Chem. 2001 Dec 7;276(49):45969-78. doi: 10.1074/jbc.M104116200. Epub 2001 Oct 2. J Biol Chem. 2001. PMID: 11583990 Free article.
Histidine 407, a phantom residue in the E1 subunit of the Escherichia coli pyruvate dehydrogenase complex, activates reductive acetylation of lipoamide on the E2 subunit. An explanation for conservation of active sites between the E1 subunit and transketolase.
Nemeria N, Arjunan P, Brunskill A, Sheibani F, Wei W, Yan Y, Zhang S, Jordan F, Furey W. Nemeria N, et al. Among authors: jordan f. Biochemistry. 2002 Dec 31;41(52):15459-67. doi: 10.1021/bi0205909. Biochemistry. 2002. PMID: 12501174
Expression and purification of the dihydrolipoamide acetyltransferase and dihydrolipoamide dehydrogenase subunits of the Escherichia coli pyruvate dehydrogenase multienzyme complex: a mass spectrometric assay for reductive acetylation of dihydrolipoamide acetyltransferase.
Wei W, Li H, Nemeria N, Jordan F. Wei W, et al. Among authors: jordan f. Protein Expr Purif. 2003 Mar;28(1):140-50. doi: 10.1016/s1046-5928(02)00674-5. Protein Expr Purif. 2003. PMID: 12651118
574 results