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Page 1
Insulin-like growth factor 2 (IGF2) protects against Huntington's disease through the extracellular disposal of protein aggregates.
García-Huerta P, Troncoso-Escudero P, Wu D, Thiruvalluvan A, Cisternas-Olmedo M, Henríquez DR, Plate L, Chana-Cuevas P, Saquel C, Thielen P, Longo KA, Geddes BJ, Lederkremer GZ, Sharma N, Shenkman M, Naphade S, Sardi SP, Spichiger C, Richter HG, Court FA, Tshilenge KT, Ellerby LM, Wiseman RL, Gonzalez-Billault C, Bergink S, Vidal RL, Hetz C. García-Huerta P, et al. Among authors: geddes bj. Acta Neuropathol. 2020 Nov;140(5):737-764. doi: 10.1007/s00401-020-02183-1. Epub 2020 Jul 8. Acta Neuropathol. 2020. PMID: 32642868 Free PMC article.
Pharmacologic inhibition of ghrelin receptor signaling is insulin sparing and promotes insulin sensitivity.
Longo KA, Govek EK, Nolan A, McDonagh T, Charoenthongtrakul S, Giuliana DJ, Morgan K, Hixon J, Zhou C, Kelder B, Kopchick JJ, Saunders JO, Navia MA, Curtis R, DiStefano PS, Geddes BJ. Longo KA, et al. Among authors: geddes bj. J Pharmacol Exp Ther. 2011 Oct;339(1):115-24. doi: 10.1124/jpet.111.183764. Epub 2011 Jul 20. J Pharmacol Exp Ther. 2011. PMID: 21775475
The 24-hour respiratory quotient predicts energy intake and changes in body mass.
Longo KA, Charoenthongtrakul S, Giuliana DJ, Govek EK, McDonagh T, Distefano PS, Geddes BJ. Longo KA, et al. Among authors: geddes bj. Am J Physiol Regul Integr Comp Physiol. 2010 Mar;298(3):R747-54. doi: 10.1152/ajpregu.00476.2009. Epub 2009 Dec 16. Am J Physiol Regul Integr Comp Physiol. 2010. PMID: 20018821 Free article.
Enhanced gastrointestinal motility with orally active ghrelin receptor agonists.
Charoenthongtrakul S, Giuliana D, Longo KA, Govek EK, Nolan A, Gagne S, Morgan K, Hixon J, Flynn N, Murphy BJ, Hernández AS, Li J, Tino JA, Gordon DA, DiStefano PS, Geddes BJ. Charoenthongtrakul S, et al. Among authors: geddes bj. J Pharmacol Exp Ther. 2009 Jun;329(3):1178-86. doi: 10.1124/jpet.108.150193. Epub 2009 Feb 27. J Pharmacol Exp Ther. 2009. PMID: 19252061
Identification of aminopiperidine benzamides as MCHr1 antagonists.
Vasudevan A, Verzal MK, Wodka D, Souers AJ, Blackburn C, Che JL, Lai S, Brodjian S, Falls DH, Dayton BD, Govek E, Daniels T, Geddes B, Marsh KC, Hernandez LE, Collins CA, Kym PR. Vasudevan A, et al. Bioorg Med Chem Lett. 2005 Jul 15;15(14):3412-6. doi: 10.1016/j.bmcl.2005.05.023. Bioorg Med Chem Lett. 2005. PMID: 15950463
34 results