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Insulin-like growth factor 2 (IGF2) protects against Huntington's disease through the extracellular disposal of protein aggregates.
García-Huerta P, Troncoso-Escudero P, Wu D, Thiruvalluvan A, Cisternas-Olmedo M, Henríquez DR, Plate L, Chana-Cuevas P, Saquel C, Thielen P, Longo KA, Geddes BJ, Lederkremer GZ, Sharma N, Shenkman M, Naphade S, Sardi SP, Spichiger C, Richter HG, Court FA, Tshilenge KT, Ellerby LM, Wiseman RL, Gonzalez-Billault C, Bergink S, Vidal RL, Hetz C. García-Huerta P, et al. Acta Neuropathol. 2020 Nov;140(5):737-764. doi: 10.1007/s00401-020-02183-1. Epub 2020 Jul 8. Acta Neuropathol. 2020. PMID: 32642868 Free PMC article.
BH3-only proteins are part of a regulatory network that control the sustained signalling of the unfolded protein response sensor IRE1α.
Rodriguez DA, Zamorano S, Lisbona F, Rojas-Rivera D, Urra H, Cubillos-Ruiz JR, Armisen R, Henriquez DR, Cheng EH, Letek M, Vaisar T, Irrazabal T, Gonzalez-Billault C, Letai A, Pimentel-Muiños FX, Kroemer G, Hetz C. Rodriguez DA, et al. EMBO J. 2012 May 16;31(10):2322-35. doi: 10.1038/emboj.2012.84. Epub 2012 Apr 17. EMBO J. 2012. PMID: 22510886 Free PMC article.
The role of small GTPases in neuronal morphogenesis and polarity.
Gonzalez-Billault C, Muñoz-Llancao P, Henriquez DR, Wojnacki J, Conde C, Caceres A. Gonzalez-Billault C, et al. Cytoskeleton (Hoboken). 2012 Jul;69(7):464-85. doi: 10.1002/cm.21034. Epub 2012 Jun 12. Cytoskeleton (Hoboken). 2012. PMID: 22605667 Review.
Cdk5 regulates Rap1 activity.
Utreras E, Henriquez D, Contreras-Vallejos E, Olmos C, Di Genova A, Maass A, Kulkarni AB, Gonzalez-Billault C. Utreras E, et al. Neurochem Int. 2013 May;62(6):848-53. doi: 10.1016/j.neuint.2013.02.011. Epub 2013 Feb 13. Neurochem Int. 2013. PMID: 23416045 Free PMC article.
111 results