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The minor gentamicin complex component, X2, is a potent premature stop codon readthrough molecule with therapeutic potential.
Friesen WJ, Johnson B, Sierra J, Zhuo J, Vazirani P, Xue X, Tomizawa Y, Baiazitov R, Morrill C, Ren H, Babu S, Moon YC, Branstrom A, Mollin A, Hedrick J, Sheedy J, Elfring G, Weetall M, Colacino JM, Welch EM, Peltz SW. Friesen WJ, et al. Among authors: johnson b. PLoS One. 2018 Oct 25;13(10):e0206158. doi: 10.1371/journal.pone.0206158. eCollection 2018. PLoS One. 2018. PMID: 30359426 Free PMC article.
The nucleoside analog clitocine is a potent and efficacious readthrough agent.
Friesen WJ, Trotta CR, Tomizawa Y, Zhuo J, Johnson B, Sierra J, Roy B, Weetall M, Hedrick J, Sheedy J, Takasugi J, Moon YC, Babu S, Baiazitov R, Leszyk JD, Davis TW, Colacino JM, Peltz SW, Welch EM. Friesen WJ, et al. Among authors: johnson b. RNA. 2017 Apr;23(4):567-577. doi: 10.1261/rna.060236.116. Epub 2017 Jan 17. RNA. 2017. PMID: 28096517 Free PMC article.
Ataluren stimulates ribosomal selection of near-cognate tRNAs to promote nonsense suppression.
Roy B, Friesen WJ, Tomizawa Y, Leszyk JD, Zhuo J, Johnson B, Dakka J, Trotta CR, Xue X, Mutyam V, Keeling KM, Mobley JA, Rowe SM, Bedwell DM, Welch EM, Jacobson A. Roy B, et al. Among authors: johnson b. Proc Natl Acad Sci U S A. 2016 Nov 1;113(44):12508-12513. doi: 10.1073/pnas.1605336113. Epub 2016 Oct 4. Proc Natl Acad Sci U S A. 2016. PMID: 27702906 Free PMC article.
Nectin-4 Expression in Prostatic Adenocarcinoma: An Immunohistochemical Study.
Baraban EG, Vlachou E, Patel S, Kates M, Johnson B, Smith A, Shenderov E, Sharma S, Denmeade SR, Brame A, Han M, De Marzo AM, Matoso A, Hoffman-Censits J. Baraban EG, et al. Among authors: johnson b. Prostate. 2025 Jan 2. doi: 10.1002/pros.24846. Online ahead of print. Prostate. 2025. PMID: 39748460
7,869 results