Lee CM - Search Results

1

Metabolic engineering generates a transgene-free safety switch for cell therapy.

Wiebking V, Patterson JO, Martin R, Chanda MK, Lee CM, Srifa W, Bao G, Porteus MH. Wiebking V, et al. Among authors: lee cm. Nat Biotechnol. 2020 Dec;38(12):1441-1450. doi: 10.1038/s41587-020-0580-6. Epub 2020 Jul 13. Nat Biotechnol. 2020. PMID: 32661439

2

Controlled delivery of β-globin-targeting TALENs and CRISPR/Cas9 into mammalian cells for genome editing using microinjection.

Cottle RN, Lee CM, Archer D, Bao G. Cottle RN, et al. Among authors: lee cm. Sci Rep. 2015 Nov 12;5:16031. doi: 10.1038/srep16031. Sci Rep. 2015. PMID: 26558999 Free PMC article.

3

Streptococcus thermophilus CRISPR-Cas9 Systems Enable Specific Editing of the Human Genome.

Müller M, Lee CM, Gasiunas G, Davis TH, Cradick TJ, Siksnys V, Bao G, Cathomen T, Mussolino C. Müller M, et al. Among authors: lee cm. Mol Ther. 2016 Mar;24(3):636-44. doi: 10.1038/mt.2015.218. Epub 2015 Dec 14. Mol Ther. 2016. PMID: 26658966 Free PMC article.

4

Nuclease Target Site Selection for Maximizing On-target Activity and Minimizing Off-target Effects in Genome Editing.

Lee CM, Cradick TJ, Fine EJ, Bao G. Lee CM, et al. Mol Ther. 2016 Mar;24(3):475-87. doi: 10.1038/mt.2016.1. Epub 2016 Jan 11. Mol Ther. 2016. PMID: 26750397 Free PMC article. Review.

5

The Neisseria meningitidis CRISPR-Cas9 System Enables Specific Genome Editing in Mammalian Cells.

Lee CM, Cradick TJ, Bao G. Lee CM, et al. Mol Ther. 2016 Mar;24(3):645-54. doi: 10.1038/mt.2016.8. Epub 2016 Jan 19. Mol Ther. 2016. PMID: 26782639 Free PMC article.

6

A Burden of Rare Variants Associated with Extremes of Gene Expression in Human Peripheral Blood.

Zhao J, Akinsanmi I, Arafat D, Cradick TJ, Lee CM, Banskota S, Marigorta UM, Bao G, Gibson G. Zhao J, et al. Among authors: lee cm. Am J Hum Genet. 2016 Feb 4;98(2):299-309. doi: 10.1016/j.ajhg.2015.12.023. Am J Hum Genet. 2016. PMID: 26849112 Free PMC article.

7

Treating hemoglobinopathies using gene-correction approaches: promises and challenges.

Cottle RN, Lee CM, Bao G. Cottle RN, et al. Among authors: lee cm. Hum Genet. 2016 Sep;135(9):993-1010. doi: 10.1007/s00439-016-1696-0. Epub 2016 Jun 17. Hum Genet. 2016. PMID: 27314256 Free PMC article. Review.

8

Design and Validation of CRISPR/Cas9 Systems for Targeted Gene Modification in Induced Pluripotent Stem Cells.

Lee CM, Zhu H, Davis TH, Deshmukh H, Bao G. Lee CM, et al. Methods Mol Biol. 2017;1498:3-21. doi: 10.1007/978-1-4939-6472-7_1. Methods Mol Biol. 2017. PMID: 27709565

9

Genome editing for inborn errors of metabolism: advancing towards the clinic.

Schneller JL, Lee CM, Bao G, Venditti CP. Schneller JL, et al. Among authors: lee cm. BMC Med. 2017 Feb 27;15(1):43. doi: 10.1186/s12916-017-0798-4. BMC Med. 2017. PMID: 28238287 Free PMC article. Review.

10

Somatic genome editing with CRISPR/Cas9 generates and corrects a metabolic disease.

Jarrett KE, Lee CM, Yeh YH, Hsu RH, Gupta R, Zhang M, Rodriguez PJ, Lee CS, Gillard BK, Bissig KD, Pownall HJ, Martin JF, Bao G, Lagor WR. Jarrett KE, et al. Among authors: lee cm, lee cs. Sci Rep. 2017 Mar 16;7:44624. doi: 10.1038/srep44624. Sci Rep. 2017. PMID: 28300165 Free PMC article.

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