Eng C - Search Results

1

A Network Medicine Approach to Investigation and Population-based Validation of Disease Manifestations and Drug Repurposing for COVID-19.

Zhou Y, Hou Y, Shen J, Kallianpur A, Zein J, Culver DA, Farha S, Comhair S, Fiocchi C, Gack MU, Mehra R, Stappenbeck T, Chan T, Eng C, Jung JU, Jehi L, Erzurum S, Cheng F. Zhou Y, et al. Among authors: eng c. ChemRxiv [Preprint]. 2020 Jul 2. doi: 10.26434/chemrxiv.12579137. ChemRxiv. 2020. Update in: PLoS Biol. 2020 Nov 6;18(11):e3000970. doi: 10.1371/journal.pbio.3000970 PMID: 32676577 Free PMC article. Updated. Preprint.

2

Characterization of the colorectal cancer-associated enhancer MYC-335 at 8q24: the role of rs67491583.

Tuupanen S, Yan J, Turunen M, Gylfe AE, Kaasinen E, Li L, Eng C, Culver DA, Kalady MF, Pennison MJ, Pasche B, Manne U, de la Chapelle A, Hampel H, Henderson BE, Marchand LL, Hautaniemi S, Askhtorab H, Smoot D, Sandler RS, Keku T, Kupfer SS, Ellis NA, Haiman CA, Taipale J, Aaltonen LA. Tuupanen S, et al. Among authors: eng c. Cancer Genet. 2012 Jan-Feb;205(1-2):25-33. doi: 10.1016/j.cancergen.2012.01.005. Cancer Genet. 2012. PMID: 22429595 Free PMC article.

3

Pulmonary arterial hypertension in a patient with Cowden syndrome and the PTEN mutation.

Ha D, Mester J, Eng C, Farha S. Ha D, et al. Among authors: eng c. Pulm Circ. 2014 Dec;4(4):728-31. doi: 10.1086/678552. Pulm Circ. 2014. PMID: 25610608 Free PMC article.

4

Preliminary report: Late seizure recurrence years after epilepsy surgery may be associated with alterations in brain tissue transcriptome.

Jehi L, Yehia L, Peterson C, Niazi F, Busch R, Prayson R, Ying Z, Bingaman W, Najm I, Eng C. Jehi L, et al. Among authors: eng c. Epilepsia Open. 2018 May 17;3(2):299-304. doi: 10.1002/epi4.12119. eCollection 2018 Jun. Epilepsia Open. 2018. PMID: 29881812 Free PMC article.

5

Personal Mutanomes Meet Modern Oncology Drug Discovery and Precision Health.

Cheng F, Liang H, Butte AJ, Eng C, Nussinov R. Cheng F, et al. Among authors: eng c. Pharmacol Rev. 2019 Jan;71(1):1-19. doi: 10.1124/pr.118.016253. Epub 2018 Dec 13. Pharmacol Rev. 2019. PMID: 30545954 Free PMC article. Review.

6

PTEN Mutations Trigger Resistance to Immunotherapy.

Cheng F, Eng C. Cheng F, et al. Among authors: eng c. Trends Mol Med. 2019 Jun;25(6):461-463. doi: 10.1016/j.molmed.2019.03.003. Epub 2019 Mar 27. Trends Mol Med. 2019. PMID: 30928438

7

Conformational Dynamics and Allosteric Regulation Landscapes of Germline PTEN Mutations Associated with Autism Compared to Those Associated with Cancer.

Smith IN, Thacker S, Seyfi M, Cheng F, Eng C. Smith IN, et al. Among authors: eng c. Am J Hum Genet. 2019 May 2;104(5):861-878. doi: 10.1016/j.ajhg.2019.03.009. Epub 2019 Apr 18. Am J Hum Genet. 2019. PMID: 31006514 Free PMC article.

8

A Systems Pharmacology Approach Uncovers Wogonoside as an Angiogenesis Inhibitor of Triple-Negative Breast Cancer by Targeting Hedgehog Signaling.

Huang Y, Fang J, Lu W, Wang Z, Wang Q, Hou Y, Jiang X, Reizes O, Lathia J, Nussinov R, Eng C, Cheng F. Huang Y, et al. Among authors: eng c. Cell Chem Biol. 2019 Aug 15;26(8):1143-1158.e6. doi: 10.1016/j.chembiol.2019.05.004. Epub 2019 Jun 6. Cell Chem Biol. 2019. PMID: 31178408 Free PMC article.

9

A genome-wide positioning systems network algorithm for in silico drug repurposing.

Cheng F, Lu W, Liu C, Fang J, Hou Y, Handy DE, Wang R, Zhao Y, Yang Y, Huang J, Hill DE, Vidal M, Eng C, Loscalzo J. Cheng F, et al. Among authors: eng c. Nat Commun. 2019 Aug 2;10(1):3476. doi: 10.1038/s41467-019-10744-6. Nat Commun. 2019. PMID: 31375661 Free PMC article.

10

Individualized genetic network analysis reveals new therapeutic vulnerabilities in 6,700 cancer genomes.

Liu C, Zhao J, Lu W, Dai Y, Hockings J, Zhou Y, Nussinov R, Eng C, Cheng F. Liu C, et al. Among authors: eng c. PLoS Comput Biol. 2020 Feb 26;16(2):e1007701. doi: 10.1371/journal.pcbi.1007701. eCollection 2020 Feb. PLoS Comput Biol. 2020. PMID: 32101536 Free PMC article.

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