SARS-CoV-2 infection of human ACE2-transgenic mice causes severe lung inflammation and impaired function.
Winkler ES, Bailey AL, Kafai NM, Nair S, McCune BT, Yu J, Fox JM, Chen RE, Earnest JT, Keeler SP, Ritter JH, Kang LI, Dort S, Robichaud A, Head R, Holtzman MJ, Diamond MS.
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Nat Immunol. 2020 Nov;21(11):1327-1335. doi: 10.1038/s41590-020-0778-2. Epub 2020 Aug 24.
Nat Immunol. 2020.
PMID: 32839612
Free PMC article.