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SARS-CoV-2 infection induces germinal center responses with robust stimulation of CD4 T follicular helper cells in rhesus macaques.
Elizaldi SR, Lakshmanappa YS, Roh JW, Schmidt BA, Carroll TD, Weaver KD, Smith JC, Deere JD, Dutra J, Stone M, Sammak RL, Olstad KJ, Reader JR, Ma ZM, Nguyen NK, Watanabe J, Usachaenko J, Immareddy R, Yee JL, Weiskopf D, Sette A, Hartigan-O'Connor D, McSorley SJ, Morrison JH, Tran NK, Simmons G, Busch MP, Kozlowski PA, Van Rompay KKA, Miller CJ, Iyer SS. Elizaldi SR, et al. Among authors: kozlowski pa. bioRxiv [Preprint]. 2020 Jul 8:2020.07.07.191007. doi: 10.1101/2020.07.07.191007. bioRxiv. 2020. Update in: Nat Commun. 2021 Jan 22;12(1):541. doi: 10.1038/s41467-020-20642-x PMID: 32676606 Free PMC article. Updated. Preprint.
A neonatal oral Mycobacterium tuberculosis-SIV prime / intramuscular MVA-SIV boost combination vaccine induces both SIV and Mtb-specific immune responses in infant macaques.
Jensen K, Pena MG, Wilson RL, Ranganathan UD, Jacobs WR Jr, Fennelly G, Larsen M, Van Rompay KK, Kozlowski PA, Abel K. Jensen K, et al. Among authors: kozlowski pa. Trials Vaccinol. 2013 Nov 1;2:53-63. doi: 10.1016/j.trivac.2013.09.005. Trials Vaccinol. 2013. PMID: 24454591 Free PMC article.
A simultaneous oral and intramuscular prime/sublingual boost with a DNA/Modified Vaccinia Ankara viral vector-based vaccine induces simian immunodeficiency virus-specific systemic and mucosal immune responses in juvenile rhesus macaques.
Curtis AD 2nd, Jensen K, Van Rompay KKA, Amara RR, Kozlowski PA, De Paris K. Curtis AD 2nd, et al. Among authors: kozlowski pa. J Med Primatol. 2018 Oct;47(5):288-297. doi: 10.1111/jmp.12372. Epub 2018 Sep 11. J Med Primatol. 2018. PMID: 30204253 Free PMC article.
Impact of Th1 CD4 Follicular Helper T Cell Skewing on Antibody Responses to an HIV-1 Vaccine in Rhesus Macaques.
Verma A, Schmidt BA, Elizaldi SR, Nguyen NK, Walter KA, Beck Z, Trinh HV, Dinasarapu AR, Lakshmanappa YS, Rane NN, Matyas GR, Rao M, Shen X, Tomaras GD, LaBranche CC, Reimann KA, Foehl DH, Gach JS, Forthal DN, Kozlowski PA, Amara RR, Iyer SS. Verma A, et al. Among authors: kozlowski pa. J Virol. 2020 Feb 28;94(6):e01737-19. doi: 10.1128/JVI.01737-19. Print 2020 Feb 28. J Virol. 2020. PMID: 31827000 Free PMC article.
SARS-CoV-2 induces robust germinal center CD4 T follicular helper cell responses in rhesus macaques.
Shaan Lakshmanappa Y, Elizaldi SR, Roh JW, Schmidt BA, Carroll TD, Weaver KD, Smith JC, Verma A, Deere JD, Dutra J, Stone M, Franz S, Sammak RL, Olstad KJ, Rachel Reader J, Ma ZM, Nguyen NK, Watanabe J, Usachenko J, Immareddy R, Yee JL, Weiskopf D, Sette A, Hartigan-O'Connor D, McSorley SJ, Morrison JH, Tran NK, Simmons G, Busch MP, Kozlowski PA, Van Rompay KKA, Miller CJ, Iyer SS. Shaan Lakshmanappa Y, et al. Among authors: kozlowski pa. Nat Commun. 2021 Jan 22;12(1):541. doi: 10.1038/s41467-020-20642-x. Nat Commun. 2021. PMID: 33483492 Free PMC article.
SARS-CoV-2 vaccines elicit durable immune responses in infant rhesus macaques.
Garrido C, Curtis AD 2nd, Dennis M, Pathak SH, Gao H, Montefiori D, Tomai M, Fox CB, Kozlowski PA, Scobey T, Munt JE, Mallory ML, Saha PT, Hudgens MG, Lindesmith LC, Baric RS, Abiona OM, Graham B, Corbett KS, Edwards D, Carfi A, Fouda G, Van Rompay KKA, De Paris K, Permar SR. Garrido C, et al. Among authors: kozlowski pa. Sci Immunol. 2021 Jun 15;6(60):eabj3684. doi: 10.1126/sciimmunol.abj3684. Sci Immunol. 2021. PMID: 34131024 Free PMC article.
Monoclonal antibodies protect aged rhesus macaques from SARS-CoV-2-induced immune activation and neuroinflammation.
Verma A, Hawes CE, Lakshmanappa YS, Roh JW, Schmidt BA, Dutra J, Louie W, Liu H, Ma ZM, Watanabe JK, Usachenko JL, Immareddy R, Sammak RL, Pollard R, Reader JR, Olstad KJ, Coffey LL, Kozlowski PA, Hartigan-O'Connor DJ, Nussenzweig M, Van Rompay KKA, Morrison JH, Iyer SS. Verma A, et al. Among authors: kozlowski pa. Cell Rep. 2021 Nov 2;37(5):109942. doi: 10.1016/j.celrep.2021.109942. Epub 2021 Oct 19. Cell Rep. 2021. PMID: 34706272 Free PMC article.
Infant rhesus macaques immunized against SARS-CoV-2 are protected against heterologous virus challenge 1 year later.
Milligan EC, Olstad K, Williams CA, Mallory M, Cano P, Cross KA, Munt JE, Garrido C, Lindesmith L, Watanabe J, Usachenko JL, Hopkins L, Immareddy R, Shaan Lakshmanappa Y, Elizaldi SR, Roh JW, Sammak RL, Pollard RE, Yee JL, Herbek S, Scobey T, Miehlke D, Fouda G, Ferrari G, Gao H, Shen X, Kozlowski PA, Montefiori D, Hudgens MG, Edwards DK, Carfi A, Corbett KS, Graham BS, Fox CB, Tomai M, Iyer SS, Baric R, Reader R, Dittmer DP, Van Rompay KKA, Permar SR, De Paris K. Milligan EC, et al. Among authors: kozlowski pa. Sci Transl Med. 2023 Mar;15(685):eadd6383. doi: 10.1126/scitranslmed.add6383. Epub 2023 Mar 1. Sci Transl Med. 2023. PMID: 36454813 Free PMC article.
91 results