Heinzlmeir S - Search Results

1

Dissecting the sequence determinants for dephosphorylation by the catalytic subunits of phosphatases PP1 and PP2A.

Hoermann B, Kokot T, Helm D, Heinzlmeir S, Chojnacki JE, Schubert T, Ludwig C, Berteotti A, Kurzawa N, Kuster B, Savitski MM, Köhn M. Hoermann B, et al. Among authors: heinzlmeir s. Nat Commun. 2020 Jul 17;11(1):3583. doi: 10.1038/s41467-020-17334-x. Nat Commun. 2020. PMID: 32681005 Free PMC article.

2

Proteome activity landscapes of tumor cell lines determine drug responses.

Frejno M, Meng C, Ruprecht B, Oellerich T, Scheich S, Kleigrewe K, Drecoll E, Samaras P, Hogrebe A, Helm D, Mergner J, Zecha J, Heinzlmeir S, Wilhelm M, Dorn J, Kvasnicka HM, Serve H, Weichert W, Kuster B. Frejno M, et al. Among authors: heinzlmeir s. Nat Commun. 2020 Jul 20;11(1):3639. doi: 10.1038/s41467-020-17336-9. Nat Commun. 2020. PMID: 32686665 Free PMC article.

3

PROTAC-mediated degradation reveals a non-catalytic function of AURORA-A kinase.

Adhikari B, Bozilovic J, Diebold M, Schwarz JD, Hofstetter J, Schröder M, Wanior M, Narain A, Vogt M, Dudvarski Stankovic N, Baluapuri A, Schönemann L, Eing L, Bhandare P, Kuster B, Schlosser A, Heinzlmeir S, Sotriffer C, Knapp S, Wolf E. Adhikari B, et al. Among authors: heinzlmeir s. Nat Chem Biol. 2020 Nov;16(11):1179-1188. doi: 10.1038/s41589-020-00652-y. Epub 2020 Sep 28. Nat Chem Biol. 2020. PMID: 32989298 Free PMC article.

4

Robust, reproducible and quantitative analysis of thousands of proteomes by micro-flow LC-MS/MS.

Bian Y, Zheng R, Bayer FP, Wong C, Chang YC, Meng C, Zolg DP, Reinecke M, Zecha J, Wiechmann S, Heinzlmeir S, Scherr J, Hemmer B, Baynham M, Gingras AC, Boychenko O, Kuster B. Bian Y, et al. Among authors: heinzlmeir s. Nat Commun. 2020 Jan 9;11(1):157. doi: 10.1038/s41467-019-13973-x. Nat Commun. 2020. PMID: 31919466 Free PMC article.

5

Chemical Proteomics Reveals Ferrochelatase as a Common Off-target of Kinase Inhibitors.

Klaeger S, Gohlke B, Perrin J, Gupta V, Heinzlmeir S, Helm D, Qiao H, Bergamini G, Handa H, Savitski MM, Bantscheff M, Médard G, Preissner R, Kuster B. Klaeger S, et al. Among authors: heinzlmeir s. ACS Chem Biol. 2016 May 20;11(5):1245-54. doi: 10.1021/acschembio.5b01063. Epub 2016 Feb 25. ACS Chem Biol. 2016. PMID: 26863403

6

New affinity probe targeting VEGF receptors for kinase inhibitor selectivity profiling by chemical proteomics.

Ku X, Heinzlmeir S, Helm D, Médard G, Kuster B. Ku X, et al. Among authors: heinzlmeir s. J Proteome Res. 2014 May 2;13(5):2445-52. doi: 10.1021/pr401247t. Epub 2014 Apr 22. J Proteome Res. 2014. PMID: 24712744

7

DENEDDYLASE1 deconjugates NEDD8 from non-cullin protein substrates in Arabidopsis thaliana.

Mergner J, Heinzlmeir S, Kuster B, Schwechheimer C. Mergner J, et al. Among authors: heinzlmeir s. Plant Cell. 2015 Mar;27(3):741-53. doi: 10.1105/tpc.114.135996. Epub 2015 Mar 17. Plant Cell. 2015. PMID: 25783028 Free PMC article.

8

Chemical Proteomics and Structural Biology Define EPHA2 Inhibition by Clinical Kinase Drugs.

Heinzlmeir S, Kudlinzki D, Sreeramulu S, Klaeger S, Gande SL, Linhard V, Wilhelm M, Qiao H, Helm D, Ruprecht B, Saxena K, Médard G, Schwalbe H, Kuster B. Heinzlmeir S, et al. ACS Chem Biol. 2016 Dec 16;11(12):3400-3411. doi: 10.1021/acschembio.6b00709. Epub 2016 Nov 7. ACS Chem Biol. 2016. PMID: 27768280

9

CiRCus: A Framework to Enable Classification of Complex High-Throughput Experiments.

Seefried F, Schmidt T, Reinecke M, Heinzlmeir S, Kuster B, Wilhelm M. Seefried F, et al. Among authors: heinzlmeir s. J Proteome Res. 2019 Apr 5;18(4):1486-1493. doi: 10.1021/acs.jproteome.8b00724. Epub 2019 Mar 22. J Proteome Res. 2019. PMID: 30799618

10

Radiosensitization by Kinase Inhibition Revealed by Phosphoproteomic Analysis of Pancreatic Cancer Cells.

Wiechmann S, Saupp E, Schilling D, Heinzlmeir S, Schneider G, Schmid RM, Combs SE, Kuster B, Dobiasch S. Wiechmann S, et al. Among authors: heinzlmeir s. Mol Cell Proteomics. 2020 Oct;19(10):1649-1663. doi: 10.1074/mcp.RA120.002046. Epub 2020 Jul 10. Mol Cell Proteomics. 2020. PMID: 32651227 Free PMC article.

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