Yang L - Search Results

1

Discovery of Phthalazinone Derivatives as Novel Hepatitis B Virus Capsid Inhibitors.

Chen W, Liu F, Zhao Q, Ma X, Lu D, Li H, Zeng Y, Tong X, Zeng L, Liu J, Yang L, Zuo J, Hu Y. Chen W, et al. Among authors: yang l. J Med Chem. 2020 Aug 13;63(15):8134-8145. doi: 10.1021/acs.jmedchem.0c00346. Epub 2020 Jul 21. J Med Chem. 2020. PMID: 32692159

2

Periplocoside A, a pregnane glycoside from Periploca sepium Bge, prevents concanavalin A-induced mice hepatitis through inhibiting NKT-derived inflammatory cytokine productions.

Wan J, Zhu YN, Feng JQ, Chen HJ, Zhang RJ, Ni J, Chen ZH, Hou LF, Liu QF, Zhang J, Yang L, Tang W, Yang YF, Nan FJ, Zhao WM, Zuo JP. Wan J, et al. Among authors: yang l, yang yf. Int Immunopharmacol. 2008 Sep;8(9):1248-56. doi: 10.1016/j.intimp.2008.05.001. Epub 2008 Jun 2. Int Immunopharmacol. 2008. PMID: 18602071

3

Pharmacophore modeling and virtual screening for the discovery of new transforming growth factor-beta type I receptor (ALK5) inhibitors.

Ren JX, Li LL, Zou J, Yang L, Yang JL, Yang SY. Ren JX, et al. Among authors: yang sy, yang jl, yang l. Eur J Med Chem. 2009 Nov;44(11):4259-65. doi: 10.1016/j.ejmech.2009.07.008. Epub 2009 Jul 16. Eur J Med Chem. 2009. PMID: 19640613

4

Discovery of (Z)-5-(4-methoxybenzylidene)thiazolidine-2,4-dione, a readily available and orally active glitazone for the treatment of concanavalin A-induced acute liver injury of BALB/c mice.

Luo Y, Ma L, Zheng H, Chen L, Li R, He C, Yang S, Ye X, Chen Z, Li Z, Gao Y, Han J, He G, Yang L, Wei Y. Luo Y, et al. Among authors: yang s, yang l. J Med Chem. 2010 Jan 14;53(1):273-81. doi: 10.1021/jm901183d. J Med Chem. 2010. PMID: 19904929

5

Design and synthesis of novel benzimidazole derivatives as inhibitors of hepatitis B virus.

Luo Y, Yao JP, Yang L, Feng CL, Tang W, Wang GF, Zuo JP, Lu W. Luo Y, et al. Among authors: yang l. Bioorg Med Chem. 2010 Jul 15;18(14):5048-55. doi: 10.1016/j.bmc.2010.05.076. Epub 2010 Jun 1. Bioorg Med Chem. 2010. PMID: 20639110

6

Synthesis and anti-hepatitis B virus activity of a novel class of thiazolylbenzimidazole derivatives.

Luo Y, Yao JP, Yang L, Feng CL, Tang W, Wang GF, Zuo JP, Lu W. Luo Y, et al. Among authors: yang l. Arch Pharm (Weinheim). 2011 Feb;344(2):78-83. doi: 10.1002/ardp.201000167. Epub 2010 Dec 22. Arch Pharm (Weinheim). 2011. PMID: 21290423

7

Discovery and optimization of 2,4-diaminoquinazoline derivatives as a new class of potent dengue virus inhibitors.

Chao B, Tong XK, Tang W, Li DW, He PL, Garcia JM, Zeng LM, Gao AH, Yang L, Li J, Nan FJ, Jacobs M, Altmeyer R, Zuo JP, Hu YH. Chao B, et al. Among authors: yang l. J Med Chem. 2012 Apr 12;55(7):3135-43. doi: 10.1021/jm2015952. Epub 2012 Mar 26. J Med Chem. 2012. PMID: 22448770

8

Isothiafludine, a novel non-nucleoside compound, inhibits hepatitis B virus replication through blocking pregenomic RNA encapsidation.

Yang L, Shi LP, Chen HJ, Tong XK, Wang GF, Zhang YM, Wang WL, Feng CL, He PL, Zhu FH, Hao YH, Wang BJ, Yang DL, Tang W, Nan FJ, Zuo JP. Yang L, et al. Among authors: yang dl. Acta Pharmacol Sin. 2014 Mar;35(3):410-8. doi: 10.1038/aps.2013.175. Epub 2014 Feb 3. Acta Pharmacol Sin. 2014. PMID: 24487969 Free PMC article.

9

Benzimidazole derivative, BM601, a novel inhibitor of hepatitis B virus and HBsAg secretion.

Xu YB, Yang L, Wang GF, Tong XK, Wang YJ, Yu Y, Jing JF, Feng CL, He PL, Lu W, Tang W, Zuo JP. Xu YB, et al. Among authors: yang l. Antiviral Res. 2014 Jul;107:6-15. doi: 10.1016/j.antiviral.2014.04.002. Epub 2014 Apr 15. Antiviral Res. 2014. PMID: 24746457

10

A novel pyridazinone derivative inhibits hepatitis B virus replication by inducing genome-free capsid formation.

Wang YJ, Lu D, Xu YB, Xing WQ, Tong XK, Wang GF, Feng CL, He PL, Yang L, Tang W, Hu YH, Zuo JP. Wang YJ, et al. Among authors: yang l. Antimicrob Agents Chemother. 2015 Nov;59(11):7061-72. doi: 10.1128/AAC.01558-15. Epub 2015 Sep 8. Antimicrob Agents Chemother. 2015. PMID: 26349829 Free PMC article.

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